Review of single-stage surgery for orbital and parasellar infantile hemangioma in a 55-day-old infant

This publication is a case report detailing the management of a 55-day-old female infant presenting with orbital and intracranial infantile hemangioma. The intervention involved a single-stage left pterional approach designed for the simultaneous resection of both orbital and parasellar lesions. The setting and specific follow-up duration were not reported in the source text. The primary outcomes assessed included achieving a definitive histopathological diagnosis and providing relief of mass effect. Secondary outcomes focused on the resolution of proptosis, the status of neurological deficits, and the extent of lesion resection.

The main results indicated that histopathological examination confirmed the diagnosis of cellular infantile hemangioma. Following the procedure, the patient experienced complete resolution of proptosis and no neurological deficits. Additionally, total resection of the lesions was achieved. The safety profile was characterized by an uneventful recovery, with no adverse events, serious adverse events, or discontinuations reported. However, the sample size was one, which inherently limits the statistical power and generalizability of these specific outcomes.

The authors acknowledge a key limitation: the absence of a management consensus for solitary orbital and parasellar infantile hemangiomas without cutaneous manifestations. Consequently, while the practice relevance suggests that isolated intracranial or orbital infantile hemangioma should be included in the differential diagnosis of pediatric masses even without skin involvement, the evidence is restricted to this single case. Surgical resection may be considered a safe and effective primary strategy when facing diagnostic uncertainty and significant symptomatology, but clinicians should interpret these results with caution given the lack of broader comparative data.