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Gastrostomy improves nutritional status in children with neurological impairment but carries risks of complicationsGastrostomy tubes help nutrition for children with neurological impairments

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Key Takeaway
Note that gastrostomy improves nutritional status in children with neurological impairment but carries a risk of complications.

This systematic review synthesized evidence from 120 studies, involving approximately 117 cohorts, to evaluate the impact of gastrostomy compared to continued oral or nasogastric feeding in children aged 0 to 18 with neurological impairment. The review assessed nutritional, respiratory, neurodevelopmental, and caregiver-reported outcomes, as well as complications and reflux.

Regarding nutritional status, the majority of 56 studies reported improvements. However, the impact on pneumonia hospitalizations was inconsistent, showing no reduction and, in some analyses, an increase. Safety data indicated that minor complications were common, occurring in 20% to 95% of cases. Major complications were reported at 0% to 3% in cases without concurrent antireflux surgery, but these rates rose several-fold when fundoplication or jejunal extensions were added.

The authors noted significant limitations, including the fact that evidence was predominantly observational and most comparative studies carried a serious risk of bias. High heterogeneity precluded a meta-analysis of the data. While earlier placement may associate with more robust catch-up growth, this does not establish causality. Clinicians should note the potential for increased de novo reflux risk in previously reflux-free children, though this is based on limited physiological data.

Feeding a child with a neurological impairment can be a complex challenge. For many families, the goal is ensuring the child gets enough nutrients to grow and thrive. A large review of 120 different studies looked at how gastrostomy tubes—tubes placed through the abdomen into the stomach—compare to traditional oral or nasogastric feeding.

The review found that the majority of the 56 studies specifically looking at nutrition showed improvements for children using these tubes. However, the results were more mixed regarding other health factors. For example, there was no clear reduction in pneumonia hospitalizations, and some data even suggested an increase in some cases.

Safety is a major consideration for parents and doctors. While minor complications occurred in 20% to 95% of cases, major complications remained very low at 0% to 3% when no extra surgery was performed. These risks can increase if additional surgeries are added. Because much of the evidence comes from observational studies, these findings should be discussed with a medical team to weigh the benefits for a specific child.

What this means for you:
Gastrostomy tubes can improve nutrition in children with neurological impairments, but some complications can occur.

Common questions

Does a gastrostomy tube improve nutrition for children?

Yes, the majority of the 56 studies specifically looking at nutritional status showed improvements for children with neurological impairments who used a gastrostomy tube instead of oral or nasogastric feeding.

What are the risks of using a gastrostomy tube?

Minor complications were common, occurring in 20% to 95% of cases. Major complications were much rarer, occurring in only 0% to 3% of cases when no additional surgery was performed. These risks can increase if extra surgeries are added.

Does a gastrostomy tube reduce pneumonia hospitalizations?

The evidence was mixed. The review found no clear reduction in pneumonia hospitalizations, and in some specific analyses, there was actually an increase in these cases.

Study Details

Study typeMeta analysis
EvidenceLevel 1
PublishedOct 2026
View Original Abstract ↓
IntroductionGastrostomy feeding is widely used for children with neurological impairment and inadequate oral intake, but evidence across family-important outcomes has not been synthesised. Previous systematic reviews were restricted to cerebral palsy and found no controlled studies. The objective of this study is to assess gastrostomy vs. continued oral/nasogastric feeding on nutritional, respiratory, neurodevelopmental, and caregiver-reported outcomes, and to quantify complications.MethodsA PROSPERO-registered systematic review (CRD420261483110) was conducted following PRISMA 2020 guidelines. Five databases were searched to 15 July 2026 for children aged 0-18 with neurological impairment undergoing gastrostomy. Duplicate screening, data extraction, and risk-of-bias appraisal (RoB 2, ROBINS-I, JBI, CASP) were performed. Heterogeneity precluded meta-analysis; narrative synthesis prioritized study design and methodological quality over direction-of-effect vote counting.ResultsFrom 5,503 records, 120 studies (≈117 cohorts, 30 countries) met the criteria. The evidence was predominantly observational, and most comparative studies carried a serious risk of bias. Nutritional status improved in the majority of 56 studies, though earlier placement's association with more robust catch-up growth does not establish causality. Among 56 respiratory studies, smaller cohorts reported fewer infections, but the largest propensity-matched and population-linked datasets showed no reduction, and in some analyses an increase, in pneumonia hospitalisations. Minor complications were common (20%–95%). Major complications clustered at 0%–3% without concurrent antireflux surgery, but rose several-fold when fundoplication or jejunal extensions were added. Reflux outcomes (59 studies) depended on preoperative status; it is hypothesized from limited physiological data that gastrostomy may increase de novo reflux risk in previously reflux-free children, though
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