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Home-Based Core Stability Telerehabilitation Shows Feasibility for Hereditary Ataxia

Home-Based Core Stability Telerehabilitation Shows Feasibility for Hereditary Ataxia
Photo by Ahmet Kurt / Unsplash
Key Takeaway
Consider home-based CSE-TR as a feasible and safe option for hereditary ataxia, but interpret functional benefits cautiously given the pilot design.

This single-blind, two-arm randomized controlled pilot study evaluated the feasibility and preliminary effects of a home-based Core Stability Exercises via Telerehabilitation (CSE-TR) program in individuals with hereditary ataxia. Twelve participants completed the 7-week intervention, performing exercises 5 days per week. They were randomized to either a Mixed Group (MG) combining asynchronous training with weekly synchronous sessions or an Asynchronous Group (AG) receiving weekly follow-up calls.

Gait performance showed statistically significant improvements over time (p<0.0001). The MG demonstrated significant gains at 7 weeks (p=0.002) but these were not maintained at follow-up, with a significant time-by-group interaction (p=0.003). Balance confidence showed significant differences over time (p=0.046) and between groups (p=0.014), with an unexpected decline in the MG.

The program was reported as feasible and safe, though adverse events and discontinuations were not reported. Key limitations include the small sample size and pilot nature, necessitating larger trials to confirm effectiveness and optimize adherence. Clinically, home-based CSE-TR appears feasible and safe for individuals with hereditary ataxia and may offer functional benefits, but these findings are preliminary.

Study Details

Study typeRct
EvidenceLevel 2
Follow-up1.6 mo
PublishedMay 2026
View Original Abstract ↓
BackgroundCore stability exercises (CSE) have shown efficacy in improving trunk function in individuals with hereditary ataxia (HA), but adherence to home programs is often low. Telerehabilitation (TR) could facilitate remote program delivery.ObjectivesTo assess the feasibility and preliminary effects of a 7-week home-based CSE-TR in individuals with HA.MethodsIn this single-blind, two-arm randomized controlled pilot study, participants performed a CSE-TR program 5 days per week, over 7 weeks. Two TR formats were compared: the Mixed Group (MG) combined asynchronous training with weekly synchronous sessions, while the Asynchronous Group (AG) received weekly follow-up calls. Feasibility outcomes included recruitment, adherence, compliance and retention. Preliminary effects-assessed at baseline, 7 weeks, and 12 weeks-included balance, gait performance, lower limb strength, fall risk, ataxia severity, and balance confidence.ResultsTwelve individuals with HA (mean age 49.5 ± 20.6 years) completed the study with 100% of retention. Statistically significant improvements over time were observed in gait performance (p < 0.0001), the MG showed significant gains at 7 weeks (p = 0.002) that were not maintained at follow-up. A significant time × group interaction was found for gait performance favoring the MG in the short term (p = 0.003). Balance confidence showed significant differences both over time (p = 0.046) and between groups (p = 0.014), with an unexpected decline in the MG. No other outcome measures reached statistical significance.ConclusionA home-based CSE-TR program is feasible and safe for individuals with HA and may provide functional benefits. Larger trials are needed to confirm effectiveness and optimize adherence.
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