Cochrane review finds uncertain benefits of drugs for Friedreich ataxia with low-certainty evidence
Cochrane review finds little benefit for drugs treating Friedreich ataxia
This Cochrane systematic review evaluated pharmacological treatments for people with genetically-confirmed Friedreich ataxia. The analysis i…
A major review of eight studies found that most drugs for Friedreich ataxia likely make little difference to key symptoms compared to placeb…
Nicotinamide Riboside Plus Exercise Improves Fitness in Friedreich's Ataxia
Combining exercise and nicotinamide riboside improved fitness in Friedreich's ataxia patients
This phase 2 randomized trial in 66 individuals with Friedreich's ataxia found that 12 weeks of nicotinamide riboside plus exercise increase…
A 12-week trial found that combining exercise with nicotinamide riboside improved heart and lung fitness in people with Friedreich's ataxia.
Home-Based Core Stability Telerehabilitation Shows Feasibility for Hereditary Ataxia
Home-based exercises may help people with hereditary ataxia improve walking and balance confidence
This single-blind pilot RCT tested a home-based core stability exercise telerehabilitation program in 12 individuals with hereditary ataxia.
A small pilot study found that home-based stability exercises improved walking and balance confidence for people with hereditary ataxia, tho…
Longitudinal multimodal MRI identifies Friedreich ataxia progression subtypes in 111 patients and controls
Three distinct brain patterns linked to Friedreich ataxia progression
This observational cohort study analyzed 111 participants, including 54 Friedreich ataxia patients and 57 controls, using longitudinal multi…
Three distinct brain patterns linked to Friedreich ataxia progression were identified using MRI scans and genetic data in patients.