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Observational registry finds 29% hospital-associated disability in older Japanese rehabilitation patients

Observational registry finds 29% hospital-associated disability in older Japanese rehabilitation pat…
Photo by Enayet Raheem / Unsplash
Key Takeaway
Note: Observational registry shows 29% HAD prevalence in older rehabilitation patients; does not establish causation.

This prospective multicenter observational study established and assessed a hospital-associated disability (HAD) registry database across nine hospitals in Japan. The study enrolled 209 patients aged 70 years or older who were independent in activities of daily living (Katz Index = 6) before admission to general rehabilitation wards. No specific intervention or comparator was reported, as the primary aim was database establishment and quality assessment.

The main results from this registry showed that among enrolled patients, the prevalence of HAD was 29.1%. Additionally, hospital-associated dysphagia prevalence was 16.7%, and weight loss during hospitalization occurred in 75.4% of patients. The median length of stay was 19 days (IQR: 13-34), and 82.3% of patients were discharged home. These outcomes were measured from admission to discharge.

Safety and tolerability data were not reported. The study's key limitation was that variables involving body weight demonstrated comparatively higher missingness. The registry may facilitate future studies on risk factor identification, predictive model development, and early intervention strategies for HAD prevention. However, this observational study reports associations and prevalence data only; it does not test interventions or establish causal risk factors.

Study Details

Sample sizen = 209
EvidenceLevel 5
PublishedMar 2026
View Original Abstract ↓
ObjectivesHospital-associated disability (HAD) refers to a decline in activities of daily living (ADL) during hospitalization and is associated with prolonged hospital stay, higher mortality, and increased readmission rates among older adults. This study aimed to establish and assess the quality of a multicenter HAD registry database that includes detailed data on nutrition, medication, swallowing, and walking ability. MethodsThis prospective multicenter study was conducted at nine hospitals in Japan. Patients aged [≥]70 years who were independent in ADL (Katz Index = 6) before admission to a general ward for rehabilitation were enrolled. Data were collected at admission and discharge using REDCap. Assessment items included demographics, Katz Index, Functional Comorbidity Index, Clinical Frailty Scale, Global Leadership Initiative on Malnutrition (GLIM) criteria, Food Intake LEVEL Scale (FILS), and Functional Ambulation Categories. HAD was defined as a Katz Index score of less than 6 on discharge. ResultsA total of 209 patients (median age = 79.0 [75-85] years; 60.8% male) were enrolled. The prevalence of HAD, hospital-associated dysphagia, and weight loss during hospitalization was 29.1%, 16.7%, and 75.4%, respectively. Median length of stay was 19 days (IQR: 13-34), and 82.3% were discharged home. While most variables had low levels of missing data, variables involving body weight demonstrated comparatively higher missingness. ConclusionsA multicenter HAD registry database was successfully established, demonstrating the feasibility of prospective data collection across multiple institutions. This registry may facilitate future studies on risk factor identification, predictive model development, and early intervention strategies for HAD prevention.
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