This randomized controlled trial enrolled 949 mothers in rural Sichuan, China, participating in a maternal and child health program. The intervention was the Healthy Future program, where community health workers delivered a breastfeeding curriculum through monthly home visits. The comparator was not being assigned to the program.
Over 6 months postpartum, the intervention was associated with improved odds of specific breastfeeding profiles compared to never breastfed. For the always exclusive breastfeeding profile, the adjusted odds ratio was ROR = 2.61 (95% CI 1.25, 5.42). For mixed feeding until the 5th month profile, the ROR was 2.52 (95% CI 1.18, 5.39). For not breastfeeding from the 3rd month profile, the ROR was 2.82 (95% CI 1.16, 6.87). Absolute numbers for these outcomes were not reported.
Safety and tolerability were not reported; no adverse events, serious adverse events, or discontinuations were described. Key limitations include the observational nature of the association from an RCT, the specific rural Sichuan setting, and the use of cluster analysis and adjusted multinomial logistic regression.
Practice relevance is that targeted efforts are needed to help mothers initiate exclusive breastfeeding from birth and continue through month 6. Findings should not be generalized to settings outside rural Sichuan, China.
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IntroductionLongitudinal trends in breastfeeding (BF) are often overlooked in favor of binary or time-to-cessation measures. Characterizing these trends can inform promotion of sustained BF practices. We identified distinct BF profiles among participants of a maternal and child health program.MethodsThe Healthy Future program consisted of community health workers delivering a BF curriculum to mothers through monthly home visits. The program was evaluated in rural Sichuan, China with a cluster-randomized controlled trial (assigned to program versus not). We clustered 6-month postpartum trends (n = 949) of maternal-reported infant feeding using dynamic time warping. For each month, participants were categorized as either exclusive breastfeeding (EBF), mixed feeding (MF, feeding breastmilk plus other foods or liquids), or not breastfeeding (NBF). After identifying clusters, we regressed BF profiles on intervention assignment using adjusted multinomial logistic regression.ResultsCluster analysis revealed seven profiles: always EBF, always MF, never breastfed, EBF until the 5th month, MF until the 5th month, mostly EBF, and NBF from the 3rd month. The intervention was associated with improved odds of always EBF (ROR = 2.61, 95% CI 1.25, 5.42), MF until the 5th month (ROR = 2.52, 95% CI 1.18, 5.39), and NBF from the 3rd month (ROR = 2.82, 95% CI 1.16, 6.87) compared to being never breastfed. Mothers in the never breastfed cluster had the lowest age, education, BF knowledge and attitudes, and decision-making power.DiscussionCluster analyses found the intervention significantly improved EBF, particularly in mothers characterized by higher baseline educational attainment and BF knowledge. Targeted efforts are needed to help mothers initiate EBF from birth and continue EBF through month 6.