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Patient-to-patient communication reduces fear of cancer recurrence after laryngectomy in RCTPatient-led support sessions reduced fear of cancer returning after throat surgery

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Key Takeaway
Consider patient-to-peer support for FCR post-laryngectomy, but evidence lacks full statistical reporting.

In a randomized controlled trial, 85 laryngeal cancer patients who underwent total laryngectomy were assigned to one of three groups: a patient-to-patient communication model (Patients' Group, PG), standard care (Routine Group, RG), or professional psychological support (Psychologists' Group, PHG). The primary outcome was fear of cancer recurrence (FCR) measured by the FCRI at 3 months post-treatment. Secondary outcomes included anxiety/depression (HADS) and swallowing-related quality of life (SWAL-QOL) at one month post-treatment.

For the primary outcome, the PG demonstrated a 38% reduction in FCRI scores at 3 months, compared to 12% in the RG and 22% in the PHG. The abstract states this was a 'significantly greater improvement' but does not report p-values or confidence intervals. For swallowing-related quality of life at one month, SWAL-QOL scores were PG: 64.7, PHG: 51.3, and RG: 38.7.

Safety and tolerability data were not reported in the abstract. Key limitations include the lack of reported statistical significance values, confidence intervals, and baseline characteristics. The sample size of 85 is modest, and follow-up was limited to 3 months for the primary outcome.

While the patient-to-patient model showed promising relative improvements in this trial, clinicians should interpret these findings cautiously due to the incomplete statistical reporting. The approach may represent a low-cost complementary strategy, but its efficacy and safety require validation in larger studies with full outcome reporting.

Researchers wanted to see if talking with other patients could help people who had their voice box removed for cancer. They studied 85 patients who had this surgery. One group had regular meetings with other patients who had been through the same thing. Another group got standard care, and a third group got support from psychologists.

After three months, the patients who met with peers reported the biggest drop in their fear that the cancer might come back. Their fear scores went down by 38%, compared to a 12% drop for standard care and 22% for psychologist-led support. They also reported better swallowing-related quality of life one month after treatment.

This was a small study, and the researchers did not share the full statistical details, like p-values or confidence intervals. They also did not report any safety concerns or problems with the peer sessions. The results are promising and suggest that connecting with others who understand the experience can be very helpful. However, because the study was small and details are limited, more research is needed to confirm these findings.

What this means for you:
Peer support shows promise for reducing fear of recurrence after throat cancer surgery, but more research is needed.

Study Details

Study typeRct
Sample sizen = 25
EvidenceLevel 2
Follow-up3.0 mo
PublishedApr 2026
View Original Abstract ↓
OBJECTIVE: This study aimed to evaluate the efficacy of a patient-to-patient communication model (PPM) in reducing fear of cancer recurrence (FCR) among laryngeal cancer patients after total laryngectomy, and to explore factors influencing FCR and its relationship with swallowing-related quality of life (SWAL-QOL). METHODS: In this randomized controlled trial, 85 laryngeal cancer patients who underwent surgical treatment were divided into three groups: Routine Group (RG, n=25) receiving standard care, Patients' Group (PG, n=30) participating in patient-to-patient communication sessions, and Psychologists' Group (PHG, n=30) receiving professional psychological support. Assessments were conducted using the Fear of Cancer Recurrence Inventory (FCRI), Hospital Anxiety and Depression Scale (HADS), and SWAL-QOL questionnaire at multiple time points. RESULTS: The PG demonstrated significantly greater improvement in FCR reduction compared to both RG and PHG groups. At 3 months post-treatment, the PG showed a 38% reduction in FCRI scores versus 12% in RG and 22% in PHG. SWAL-QOL scores improved most substantially in the PG (64.7) compared to PHG (51.3) and RG (38.7) at one month post-treatment. Educational level and postoperative quality of life were identified as significant factors influencing FCR severity. CONCLUSION: The patient-to-patient communication model proves to be an effective intervention for reducing FCR in laryngectomy patients, particularly during the critical periods before surgery and within the first postoperative week. This approach offers a valuable, low-cost complementary strategy to conventional psychological support in cancer rehabilitation.
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