A systematic review and meta-analysis assessed the effectiveness of technology-based social cognition training (TBSCT) in adults with schizophrenia-spectrum disorders. The intervention utilized computerized, web-based, or virtual reality formats targeting emotion recognition, theory of mind, or empathy. Data were pooled from 21 studies, comprising 17 in the meta-analysis, though the specific setting was not reported. Methodological quality was rated as moderate to high.
Regarding primary outcomes, TBSCT significantly enhanced facial emotion recognition with a Hedges' g of 0.92 (p < 0.001). For theory of mind, the intervention showed a small effect with a Hedges' g of 0.22 (p = 0.05). Empathy scores improved from pre- to post-intervention with a Hedges' g of 0.58 (p = 0.04). Subgroup analysis indicated that facial emotion recognition benefits were strongest in web-based formats (g = 1.35), followed by virtual reality (g = 0.87) and computerized programs (g = 0.75). Theory of mind gains were significant only among outpatients.
Safety data indicated mild, transient adverse effects with no serious adverse events reported. Dropout rates were comparable between groups, with a risk difference of -0.03 (p = 0.21). The authors note that long-term efficacy was not examined and engagement across diverse psychiatric populations was not optimized. Given these limitations, the interventions are considered safe, feasible, and scalable, supporting clinical implementation.
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INTRODUCTION: Social cognition deficits, such as impaired emotion recognition, theory of mind (ToM), and empathy are central to schizophrenia-spectrum disorders and predict poor functional outcomes. Conventional therapies often lack scalability. Technology-based social cognition training (TBSCT), using computerized, web-based, or virtual reality (VR) formats, offers an accessible and adaptive solution.
METHODS: Following PRISMA guidelines (PROSPEROCRD420251021242), databases including Embase, MEDLINE, Cochrane, CINAHL, Web of Science, and PsycArticles were searched up to May 2025. Eligible randomized or quasi-experimental studies involved adults with schizophrenia-spectrum disorders receiving TBSCT targeting emotion recognition, ToM, or empathy. Methodological quality was assessed using Joanna Briggs Institute tools. Random-effects meta-analyses estimated pooled effect sizes (Hedges' g), with subgroup analyses by technology type, clinical setting, and intervention focus.
RESULTS: Twenty-one studies (17 in meta-analysis) met inclusion criteria. TBSCT significantly enhanced facial emotion recognition (FER; g = 0.92, p < 0.001) and showed a small effect on ToM (g = 0.22, p = 0.05); empathy improved pre-post (g = 0.58, p = 0.04). FER benefits were strongest in web-based (g = 1.35), followed by VR (g = 0.87) and computerized programs (g = 0.75). ToM gains were significant only among outpatients. Methodological quality was moderate to high, with mild, transient adverse effects and comparable dropout rates (risk difference = -0.03, p = 0.21).
CONCLUSION: TBSCT effectively improves social cognition, particularly emotion recognition in schizophrenia-spectrum disorders. The interventions are safe, feasible, and scalable, supporting clinical implementation. Future studies should examine long-term efficacy and optimize engagement across diverse psychiatric populations.