GLP-1RAs reduce weight and HbA1c in severe mental illness with low discontinuation rates
New drugs help people with severe mental illness lose weight safely
This systematic review and meta-analysis evaluated glucagon-like peptide-1 receptor agonists in individuals with severe mental illness who h…
New weight loss drugs work well and stay safe for people with severe mental illness who struggle with obesity and high blood sugar.
VR-CBTp and CBTp Outcomes for Schizophrenia Spectrum Disorders Paranoia in 254-Person RCT
Virtual reality therapy helps some schizophrenia patients more than standard talk therapy
This randomized controlled trial involved 254 individuals with schizophrenia spectrum disorders comparing 10-session VR-CBTp to standard CBT…
People with schizophrenia who struggle with motivation or stronger delusions may benefit more from VR therapy than standard talk therapy.
Longitudinal MRI study links brain morphometry to treatment in schizophrenia spectrum disorders
Long-Term Schizophrenia Treatment May Reshape Brain Structure, Study Shows
This observational cohort study analyzed longitudinal structural MRI data from 350 individuals with schizophrenia spectrum disorders and 193…
Time spent on schizophrenia medication physically reshapes brain structure, linking treatment duration to lasting changes in the mind's orga…
Plasma NfL levels elevated in bipolar and depressive disorders in UK Biobank cohort
Brain Scans Show Hidden Signals in Mental Health
A cohort study of 47,495 UK Biobank participants found plasma neurofilament light chain (NfL) levels were higher in bipolar disorder (d=0.20…
Blood tests now reveal hidden brain signals that distinguish depression from anxiety, offering clearer paths to the right treatment for mill…
Technology-based social cognition training improved facial emotion recognition and empathy in adults with schizophrenia-spectrum disorders.
Technology training improved social skills in adults with schizophrenia-spectrum disorders in a meta-analysis.
This systematic review and meta-analysis evaluated technology-based social cognition training (TBSCT) in adults with schizophrenia-spectrum …
Technology training helps adults with schizophrenia-spectrum disorders recognize emotions and understand others' thoughts better.
Autonomic arousal moderates network switching-cognition link in healthy controls but not schizophrenia
Does your brain's switching speed change with stress? New data suggests it might in schizophrenia.
An observational study of 105 participants (39 healthy controls, 27 psychiatric controls, 39 with schizophrenia spectrum disorders) found au…
In people with schizophrenia, stress no longer affects how brain switching connects to thinking skills, unlike in healthy individuals.
Antipsychotic exposure shows time-dependent associations with vocational recovery in schizophrenia cohort
Do antipsychotics help people with schizophrenia get back to work or school?
A Danish register-based cohort study of 65,630 individuals with incident schizophrenia spectrum disorders found antipsychotic exposure was a…
Antipsychotic medication use initially lowers work or school chances for schizophrenia patients but eventually shows a small positive link a…