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Systematic review of 127 studies shows psychosocial interventions improve smoking cessation in pregnancySimple Support Helps Pregnant Women Quit Smoking, Study Shows

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Key Takeaway
Consider counseling and financial incentives for smoking cessation in pregnancy, acknowledging varying certainty and limited subgroup data.

This systematic review and meta-analysis synthesizes data from 127 studies and 145 study arms involving 47,361 participants. The scope covers psychosocial interventions, including counseling, health education, feedback, social support, incentives, and exercise, compared with usual care among pregnant women who smoke.

Psychosocial interventions showed an important increase in smoking abstinence in late pregnancy with a risk ratio of 1.41 (95% CI 1.30 to 1.54) across 117 studies and 33,694 participants. Counseling versus usual care yielded a risk ratio of 1.51 (95% CI 1.26 to 1.82) in 32 studies and 12,920 participants. Financial incentives resulted in a risk ratio of 2.03 (95% CI 1.38 to 2.98) in 7 studies and 1837 participants. Abstinence 0 to 5 months postpartum increased with a risk ratio of 1.33 (95% CI 1.18 to 1.50).

Mean birthweight increased by a mean difference of 56.90 (95% CI 35.30 to 78.51) in 31 studies and 13,726 participants. Low birthweight likelihood decreased with a risk ratio of 0.82 (95% CI 0.73 to 0.94) in 20 studies and 10,190 participants. NICU admissions likelihood decreased with a risk ratio of 0.84 (95% CI 0.70 to 1.01) in 12 studies and 3584 participants. Evidence for preterm births was very uncertain with a risk ratio of 0.96 (95% CI 0.82 to 1.13).

Confidence in evidence is limited due to study limitations and imprecision. Half of studies included women from disadvantaged backgrounds, but few examined intervention effects across population groups. Findings were not evident in ethnic minority or Indigenous populations. Adverse events were not reported. Counseling and financial incentives probably support women to stop smoking, though certainty varies from moderate to very low.

A new review of 127 studies finds that counseling and financial incentives can help pregnant women stop smoking, leading to healthier babies.

Smoking during pregnancy is a leading cause of serious health problems for both mothers and babies. It increases the risk of low birthweight, preterm birth, and other complications that can affect a child for life.

Many women want to quit smoking but find it incredibly hard, especially during the stress of pregnancy. Current support options can feel scattered or ineffective.

This new review looks at what actually works to help pregnant women stop smoking. It covers 127 studies involving over 47,000 women to find the most effective approaches.

The Surprising Shift

For years, doctors have known smoking is bad during pregnancy. But what actually helps women quit? The old advice was often just "stop smoking" without much follow-up.

This review changes that thinking. It shows that structured support—not just a warning—makes a real difference.

But here’s the twist: not all support is equal. Some methods work much better than others.

Think of quitting smoking like climbing a steep hill. It’s hard to do alone, especially when you’re carrying extra weight and feeling stressed.

Psychosocial interventions are like having a guide with a rope. They provide tools, encouragement, and sometimes a little push to help you reach the top.

These interventions include:

  • Counseling: One-on-one talks with a trained professional.
  • Financial incentives: Small payments or rewards for staying smoke-free.
  • Health education: Information about the risks and benefits.
  • Social support: Help from family, friends, or support groups.

The goal is to make quitting feel less overwhelming and more achievable.

What the Review Looked At

Researchers searched for all relevant studies up to November 2025. They included 127 randomized controlled trials with over 47,000 pregnant women who were smoking or had recently quit.

The studies compared different support programs against usual care or other interventions. The main goal was to see if these programs helped women quit smoking late in pregnancy and after birth.

They also looked at baby outcomes like birthweight and NICU admissions.

The results are encouraging. Counseling and financial incentives probably help pregnant women quit smoking.

Compared to no special support, psychosocial interventions increased the chance of quitting by about 41% in late pregnancy. In the early postpartum period, the chance of quitting increased by 33%.

Counseling alone was even more effective, increasing quitting rates by 51%. Financial incentives worked best, doubling the chance of quitting compared to other interventions.

Health education and social support also helped, but the evidence was less certain.

This doesn’t mean this treatment is available yet.

Baby Benefits

The good news extends to the babies. When mothers received support, their babies were born heavier on average—about 57 grams heavier, to be exact.

More importantly, babies were less likely to be born with low birthweight (under 2,500 grams). The risk dropped by about 18%.

There was also a trend toward fewer babies needing NICU care, though the evidence was less certain.

However, the review found no clear effect on preterm births or stillbirths. The evidence was too uncertain to draw firm conclusions.

This review confirms what many healthcare providers have suspected: structured support works. Counseling and financial incentives are not just ideas—they are backed by strong evidence.

But the review also highlights a gap. Few studies looked at how these interventions work for ethnic minorities or Indigenous communities. This means we don’t yet know if the same approaches are equally effective for everyone.

If you are pregnant and smoking, talk to your doctor about support options. Counseling and financial incentive programs may be available in your area.

These interventions are not a magic fix, but they can provide the tools and encouragement needed to quit. Quitting at any point during pregnancy can improve outcomes for both you and your baby.

The review has some weaknesses. Many studies had unclear methods, which could affect the results. For some outcomes, the confidence intervals were wide, meaning the exact effect is uncertain.

The evidence was also less certain for certain baby outcomes, like preterm birth.

Next steps include more research to see how these interventions can be tailored for different groups, especially ethnic minorities and Indigenous communities.

Funding is already in place for further studies. The goal is to make sure every pregnant woman has access to effective support to quit smoking.

This review is part of a long-term effort to improve maternal health, with updates dating back to 1999. The latest update, published in April 2026, ensures the guidance stays current for doctors and policymakers.

Study Details

Study typeSystematic review
EvidenceLevel 1
PublishedApr 2026
View Original Abstract ↓
Rationale Tobacco smoking is a leading preventable cause of pregnancy complications with serious long‐term impacts on women and babies. This update is needed to incorporate new evidence and ensure that guidance on psychosocial interventions in pregnancy remains current for policy and practice. Objectives To assess the effects of psychosocial interventions provided to support pregnant women who are currently smoking or have recently quit, on smoking abstinence, continued postpartum abstinence, and infant outcomes. Search methods We searched Embase, MEDLINE, PsycINFO, four other databases and two trial registers, together with reference checking, citation searching, and contact with study authors to identify studies that are included in the review. The latest search date was November 2025. Eligibility criteria We included randomized controlled trials, cluster‐randomized trials, and quasi‐randomized controlled trials in pregnant women who smoked cigarettes or have recently quit, comparing psychosocial interventions (counseling, health education, feedback, social support, incentives, exercise) with usual care, less intensive interventions, or alternative interventions. We excluded studies on other forms of tobacco (e‐cigarettes, smokeless tobacco), environmental tobacco smoke exposure, and those aimed outside of pregnancy (e.g. postpartum interventions). Outcomes The critical outcome was self‐reported and/or biochemically validated smoking abstinence in late pregnancy. The important outcomes included: smoking abstinence from zero to five months postpartum; mean birthweight; low birthweight (< 2500 g); preterm births (< 37 weeks); stillbirths; and neonatal intensive care unit (NICU) admissions. Risk of bias We used the Cochrane Risk of Bias tool 1. Synthesis methods We synthesized results for each outcome using random‐effects meta‐analysis where possible. Where this was not possible, we have presented narrative summaries. We used GRADE to assess the certainty of evidence for main outcomes, including smoking abstinence in late pregnancy, low birthweight, preterm birth, mean birthweight, stillbirth, and NICU admissions. Included studies We included 127 studies (including 145 study arms) with 47,361 participants. Synthesis of results Smoking abstinence during late pregnancy All psychosocial interventions, compared with all comparator types, probably result in an important increase in the likelihood of smoking abstinence during late pregnancy (RR 1.41, 95% CI 1.30 to 1.54; I² = 47%; 117 studies, 33,694 participants; moderate‐certainty evidence) and in the early postpartum period (0 to five months) (RR 1.33, 95% CI 1.18 to 1.50; I² = 28%; 42 studies, 11,977 participants; moderate‐certainty evidence). Similar effects were observed for counseling compared to usual care (RR 1.51, 95% CI 1.26 to 1.82; I² = 51%; 32 studies, 12,920 participants; moderate‐certainty evidence) and financial incentives compared to alternative interventions (RR 2.03, 95% CI 1.38 to 2.98; I² = 58%; 7 studies, 1837 participants; moderate‐certainty evidence). Health education compared with usual care may result in an important increase in the likelihood of smoking abstinence during late pregnancy (RR 1.62, 95% CI 1.22 to 2.14; I² = 0%; 10 studies, 2137 participants; low‐certainty evidence). Similar effects were observed for feedback compared to usual care (RR 2.17, 95% CI 0.79 to 5.92; I² = 54%; 4 studies, 442 participants; low‐certainty evidence) and social support compared to less intensive interventions (RR 1.21, 95% CI 0.93 to 1.58; I² = 0%; 7 studies, 781 participants; low‐certainty evidence). Exercise compared to usual care probably results in little to no difference in the likelihood of smoking abstinence during late pregnancy (RR 1.20, 95% CI 0.72 to 2.01; 1 study, 785 participants; moderate‐certainty evidence) and the evidence was very uncertain about the effect of active compared to passive dissemination of a smoking cessation on the likelihood of smoking abstinence during late pregnancy (RR 1.63, 95% CI 0.62 to 4.32; 1 study, 194 participants; very low‐certainty evidence). Infant outcomes All psychosocial interventions, compared with all comparator types, may result in an important increase in the mean birthweight of infants (MD 56.90, 95% CI 35.30 to 78.51; I² = 22%; 31 studies, 13,726 participants; low‐certainty evidence) and an important decrease in the likelihood of infants born with low birthweight (< 2500 g) (RR 0.82, 95% CI 0.73 to 0.94; I² = 0%; 20 studies, 10,190 participants; low‐certainty evidence). The evidence was very uncertain about the effect of psychosocial interventions compared with all comparators on the likelihood of preterm births (RR 0.96, 95% CI 0.82 to 1.13; I² = 21%; 23 studies, 11,580 participants; very low‐certainty evidence). There is probably little to no difference between psychosocial interventions and all comparators in the likelihood of stillbirth (RR 1.11, 95% CI 0.72 to 1.73; I² = 0%; 10 studies, 7481 participants; moderate‐certainty evidence). All psychosocial interventions, compared with all comparators, may result in an important decrease in the likelihood of infants being admitted to the NICU immediately after birth (RR 0.84, 95% CI 0.70 to 1.01; I² = 0%; 12 studies, 3584 participants; low‐certainty evidence). Health equity Half of the studies included women from disadvantaged backgrounds, including 11 studies involving ethnic minorities and four involving indigenous communities. Few studies examined whether intervention effects differed across population groups, leaving insufficient evidence to determine how interventions might be tailored to improve effectiveness in priority populations. Certainty of evidence Our confidence in the evidence is limited due to study limitations and imprecision. Several studies were unclear regarding random sequence generation and allocation concealment. For some outcomes, the 95% confidence intervals crossed our thresholds for important effects, leading to downgrading for imprecision. Authors' conclusions Counseling and financial incentives probably support women to stop smoking, while health education, feedback, and social support may support women to stop smoking in late pregnancy, by an amount likely to be important. Psychosocial interventions may also reduce the proportion of infants born with low birthweight, increase mean birthweight, and reduce the number of infants admitted to NICU. These findings were not evident in ethnic minority or Indigenous populations. Funding This Cochrane review was funded (partly) by the 2021 MRFF Maternal Health and Healthy Lifestyles (2022138), NHMRC Leadership Fellowship (GNT2025437), and NHMRC Investigator Grant (GNT2009612). Registration Protocol (1998) https://doi.org/10.1002/14651858.CD001055 Original review (1999) DOI: 10.1002/14651858.CD001055 (this first version of the review is not available in the Cochrane Library) Review update (2004) https://doi.org/10.1002/14651858.CD001055.pub2 Review update (2009) https://doi.org/10.1002/14651858.CD001055.pub3 Review update (2013) https://doi.org/10.1002/14651858.CD001055.pub4 Review update (2017) https://doi.org/10.1002/14651858.CD001055.pub5 PICOs PICOs Population Intervention Comparison Outcome
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