Two lung transplant recipients developed Legionnaires' disease from a single donor

A case report describes two lung transplant recipients who developed Legionnaires' disease. Both patients received lung transplants from the same donor. The report documents 2 cases of Legionnaires' disease in these recipients, suggesting possible transmission from the donor. No effect sizes, p-values, or confidence intervals were reported for this association.

Safety and tolerability data, including adverse events, serious adverse events, and discontinuations, were not reported. The report does not provide information on the clinical course or outcomes for the two patients.

Key limitations include the descriptive, non-comparative nature of a case report. No comparator group was studied, and the evidence does not establish causality for donor-to-recipient transmission. The sample size was only 2 patients, and follow-up duration was not reported.

For clinical practice, this report highlights a potential risk that warrants awareness during donor evaluation and post-transplant monitoring. However, the evidence is preliminary and descriptive, offering no guidance on prevention or management strategies. Funding sources and author conflicts of interest were not reported.