Mode
Text Size
Log in / Sign up

Patient Questions

Real questions from health communities, answered with cited research from PubMed and Vellito's article corpus. Plain language, no medical advice. How this works.

Oncology

Did a patient with uveal melanoma benefit from combined tebentafusp and SBRT?

Yes, a case report describes a patient with metastatic uveal melanoma who achieved durable disease control after adding SBRT to tebentafusp, with a partial response and 35 months…

Which anti-PD-1 regimen showed the best survival for non-squamous non-small cell lung cancer?

Prolgolimab plus chemotherapy showed the strongest overall survival benefit in a 2025 phase III trial, while network meta-analysis also ranked pembrolizumab and cemiplimab plus…

Pediatrics

How do genetic factors contribute to a child's risk of otitis media?

Genetic factors increase a child's risk of chronic otitis media by altering immune system responses and middle ear function, with specific gene variants on chromosome 19…

ENT (Otolaryngology)

Do bone conduction hearing devices improve quality of life for adults with chronic otitis media?

Yes, bone conduction hearing devices significantly improve health-related quality of life for adults with chronic otitis media, based on systematic reviews and clinical studies.

Oncology

Can tebentafusp and SBRT control disease in uveal melanoma?

Yes, a case report shows tebentafusp plus SBRT controlled metastatic uveal melanoma for over 35 months, but more research is needed to confirm this approach.

Oncology

How does immunoembolization compare to the FOCUS trial for uveal melanoma?

Immunoembolization shows lower disease control rates than the FOCUS trial for liver-dominant metastatic uveal melanoma, though tebentafusp combined with radiotherapy may offer…

Infectious Disease

Do different doses of ceftriaxone change the hospital stay for bacterial infections?

A meta-analysis found no significant difference in hospital length of stay between high-dose and low-dose ceftriaxone for non-CNS infections.

Oncology

What are the survival rates for Acute Promyelocytic Leukemia treated with ATRA and ATO?

ATRA plus ATO for APL achieves 3-year overall survival of 95% and 10-year survival of ≥80%, with complete remission rates over 95%.

Does the new AI test work well for distinguishing Acute Promyelocytic Leukemia from other types?

An AI tool shows very high accuracy for distinguishing Acute Promyelocytic Leukemia (APL) from other leukemias, with an AUROC of 0.98 in international tests, though it currently…

Hematology

How effective is frontline ATRA-ATO therapy for newly diagnosed Acute Promyelocytic Leukemia?

Frontline ATRA-ATO therapy is highly effective for newly diagnosed APL, with complete remission rates over 94% and 3-year survival above 93% in clinical trials.

Infectious Disease

Did the rate of oral and pharyngeal HPV-associated cancer increase in the US between 2007 and 2016?

Yes, the rate of oral and pharyngeal HPV-associated cancer increased in the US between 2007 and 2016, likely driven by rising HPV-related cases.

Oncology

What is the objective response rate for becotatug vedotin in recurrent head and neck cancer?

Becotatug vedotin showed a 20.9% objective response rate in recurrent or metastatic head and neck squamous cell carcinoma after prior therapy.

Pulmonology & Critical Care

Can short-course antibiotics help prevent lung infections in mechanically ventilated Brain Injury patients?

Short-course beta-lactam antibiotics can reduce early lung infections in ventilated brain injury patients, but they do not prevent late-onset infections or lower death rates.

OB/GYN & Women's Health

What are the treatment options for hypertriglyceridemia during pregnancy?

Treatment for hypertriglyceridemia in pregnancy starts with strict low-fat diet and lifestyle changes; severe cases may require insulin, plasma exchange, or rarely fibrates under…

Gastroenterology

Does plozasiran reduce the risk of recurrent pancreatitis in severe hypertriglyceridemia?

Yes, plozasiran reduces the risk of recurrent pancreatitis in severe hypertriglyceridemia by 83% based on a post hoc analysis of the PALISADE trial.

Urology

Does darolutamide combination therapy improve survival for metastatic hormone-sensitive prostate cancer?

Yes, darolutamide combination therapy improves survival in metastatic hormone-sensitive prostate cancer, with a 32% reduction in risk of death when added to ADT plus docetaxel.

Urology

Can darolutamide plus ADT delay pain progression in metastatic hormone-sensitive prostate cancer?

Yes, darolutamide plus ADT significantly delays pain progression in metastatic hormone-sensitive prostate cancer, based on the ARANOTE phase 3 trial.

Pulmonology & Critical Care

Do cohort studies show clinical outcomes for pediatric acute respiratory infections?

Yes, cohort studies are the most common study type in pediatric ARI research, providing key data on pathogen profiles, co-infections, seasonal patterns, and clinical outcomes…

Infectious Disease

Which EBUS technique works best for diagnosing lymphoma in the mediastinum?

EBUS-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) has the highest diagnostic yield for lymphoma in the mediastinum, outperforming standard EBUS-TBNA.

Diabetes & Endocrinology

Does olezarsen reduce plaque volume in adults with moderate hypertriglyceridemia?

No, olezarsen did not significantly reduce noncalcified plaque volume over 12 months in adults with moderate hypertriglyceridemia, despite lowering triglycerides by ~60%.

Nephrology

Are Frexalimab, Brivekimig, and Rilzabrutinib being tested together to treat Focal Segmental Glomerulosclerosis?

No, Frexalimab, Brivekimig, and Rilzabrutinib are not being tested together. A current Phase 2 study tests these drugs individually against a placebo to see which one reduces…

Neurology

Is cerebral infarction common in children with tuberculous meningitis and severe disease?

Yes, cerebral infarction is common in children with tuberculous meningitis, especially in severe disease, with rates up to 50% in some studies.

Does arterial occlusion link cerebral infarction to disease severity in tuberculous meningitis?

Yes, arterial occlusion is a key mechanism linking cerebral infarction to disease severity in tuberculous meningitis, as shown by a secondary analysis of the ACT-TBM trial.

Gastroenterology

Is obinutuzumab an option for FSGS patients who did not respond to rituximab?

Yes, obinutuzumab has shown promise in case reports and small studies for FSGS patients who did not respond to rituximab, but larger trials are needed.

How this works

We pull real patient questions from public Reddit health communities (r/AskDocs, r/diabetes, r/menopause, etc.). Each question is rewritten into a generic medical question (no personal details), then answered by an AI using only cited sources from Vellito's article database and PubMed. A second AI independently scores each answer for accuracy and citation fidelity before publication. Answers below the safety threshold or touching emergency, dosing, or pediatric topics are queued for human review and never auto-published.

This is not medical advice. Always speak with your own doctor before making decisions about your health.