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Patient Questions

Real questions from health communities, answered with cited research from PubMed and Vellito's article corpus. Plain language, no medical advice. How this works.

Is Keytruda approved for treating unresectable or metastatic melanoma?

Yes, Keytruda (pembrolizumab) is FDA-approved for treating unresectable or metastatic melanoma.

Psychiatry

Does high-frequency music therapy reduce stress better than low-frequency sessions for psychiatric patients?

A 2024 trial found that high-frequency music therapy reduced stress better than low-frequency sessions in adult psychiatric patients, but other research shows various other…

Psychiatry

Can virtual reality interventions help reduce stress and anxiety for healthcare workers?

Yes, a meta-analysis of 10 studies found VR interventions significantly reduce stress and anxiety in healthcare workers, with moderate to large effect sizes.

Do anti-inflammatory diets like the Mediterranean diet help reduce stress symptoms?

Yes, anti-inflammatory diets like the Mediterranean diet may help reduce stress symptoms by lowering inflammation, though direct evidence is still emerging.

Can a 12-week breathwork protocol reduce stress and anxiety in paramedic students?

Yes, a 12-week breathwork protocol significantly reduced stress and anxiety in paramedic students in a randomized controlled trial.

Pulmonology & Critical Care

Does imaging help find interstitial lung disease in psoriatic arthritis patients?

Yes, imaging — especially CT or high-resolution CT — detects interstitial lung disease in psoriatic arthritis patients more often than non-imaging methods, finding it in about…

Do adults with ADHD show higher emotional eating than healthy controls?

Yes, multiple studies show adults with ADHD have significantly higher emotional eating than healthy controls, linked to impulsivity and mood issues.

How does secukinumab improve skin response in Chinese patients with psoriatic arthritis?

Secukinumab significantly improves skin clearance and quality of life in Chinese psoriatic arthritis patients, with PASI scores dropping from 14.2 to 4.0 after 12 weeks.

Pediatrics

Do speech features differ between children with ADHD and healthy controls?

Yes, children with ADHD show distinct speech features including lower and more variable pitch, altered spectral properties, reduced rhythmic stability, and higher subglottal…

What multi-omics strategies are being studied for psoriatic arthritis?

Multi-omics strategies for psoriatic arthritis combine genomics, transcriptomics, proteomics, and microbiomics to improve diagnosis, predict treatment response, and identify new…

Can targeted therapies for psoriatic arthritis change my cholesterol levels?

Yes, some targeted therapies for psoriatic arthritis can change your cholesterol levels, but the effect varies by drug class.

Do speech features in children with ADHD change after taking medication?

Yes, a small study found that speech features in children with ADHD change after taking methylphenidate, showing reduced pitch variability and improved rhythmic stability.

Does smoking increase the risk of interstitial lung disease in psoriatic arthritis?

Yes, smoking is associated with a higher risk of interstitial lung disease in psoriatic arthritis, with studies showing smoking as a significant risk factor.

Neurology

Do specific autism neurosubtypes show opposite electrical brain activity patterns in preclinical models?

Research using animal models and human EEG data indicates that autism consists of distinct neurosubtypes with opposing electrical brain activity patterns related to excitation…

Psychiatry

How does stigma in adult ADHD affect quality of life outcomes?

Stigma in adult ADHD is linked to worse quality of life across social, psychological, and occupational domains, with self-stigma and perceived stigma being particularly harmful.

Diabetes & Endocrinology

Does having a high LDL-C to HDL-C ratio increase heart risks if I have diabetic retinopathy?

Yes, a high LDL-C to HDL-C ratio (≥2.0) is linked to a higher risk of cardiovascular events in people with type 2 diabetes and diabetic retinopathy, even when taking statins.

Can smartphone images be used to screen for diabetic retinopathy in low-resource settings?

Yes, smartphone-based imaging combined with AI screening tools can effectively detect diabetic retinopathy in low-resource settings, though further real-world testing is needed.

Can a preoperative model accurately predict lateral lymph node metastasis in rectal cancer?

Yes, preoperative models using MRI and clinical data can accurately predict lateral lymph node metastasis in rectal cancer, with AUCs over 0.88 in recent studies.

Is there a link between having diabetic retinopathy and age-related macular degeneration?

Current evidence shows no significant link between diabetic retinopathy and age-related macular degeneration, despite shared risk factors.

Does using methylene blue during surgery help find more lymph nodes in rectal cancer?

Yes, injecting methylene blue into the inferior mesenteric artery during rectal cancer surgery significantly increases the number of lymph nodes detected and reduces variability…

How well do AI screening tools detect diabetic retinopathy compared to other methods?

AI screening tools detect diabetic retinopathy with high accuracy, outperforming conventional methods in meta-analyses, but real-world performance varies.

What is the risk of anastomotic leakage after anterior resection for rectal cancer?

Anastomotic leakage after anterior resection for rectal cancer occurs in about 7-10% of patients, with risk factors including male sex, higher tumor stage, and longer surgery.

Gastroenterology

Does robotic surgery offer better outcomes than laparoscopic surgery for rectal cancer?

Robotic surgery may reduce urinary retention after rectal cancer surgery, but overall functional and oncological outcomes are similar to laparoscopic surgery.

How does sleep intervention and nutrition affect survival after rectal cancer surgery?

Combined cognitive-behavioral sleep intervention and nutritional support improve sleep, reduce inflammation, and may improve 2-year survival after rectal cancer surgery.

How this works

We pull real patient questions from public Reddit health communities (r/AskDocs, r/diabetes, r/menopause, etc.). Each question is rewritten into a generic medical question (no personal details), then answered by an AI using only cited sources from Vellito's article database and PubMed. A second AI independently scores each answer for accuracy and citation fidelity before publication. Answers below the safety threshold or touching emergency, dosing, or pediatric topics are queued for human review and never auto-published.

This is not medical advice. Always speak with your own doctor before making decisions about your health.