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Peer support may impact fear of disease progression and psychological symptoms in patients with gliomaPeer support may ease fear in glioma patients

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Key Takeaway
Note that this is a study protocol; no results regarding peer support efficacy are currently available.

This publication is a protocol for a planned systematic review and meta-analysis focusing on the role of peer support for patients diagnosed with glioma. The scope of the proposed analysis includes primary outcomes related to fear of disease progression (FoP) and secondary outcomes including fatigue, depression, and anxiety.

As this is a study protocol, no data from clinical trials or observational studies have been synthesized yet. No effect sizes, p-values, or specific results regarding the efficacy of peer support are available at this time. The authors intend to evaluate how peer support influences psychological distress in the glioma population.

A primary limitation noted is that the study is a protocol for a planned meta-analysis; therefore, no data have been analyzed and no conclusions can be drawn from this specific document. Clinical practice relevance cannot be determined until the systematic review and meta-analysis are completed and results are published.

How this fits prior evidence

This protocol addresses a gap in synthesized evidence regarding the psychological impact of peer support for patients with glioma. While other covered items focus on diagnostic tools such as MRI radiomics to predict TERTp mutation or deep learning models for glioma segmentation, this planned analysis focuses specifically on patient-centered outcomes like fear of disease progression and anxiety.

Researchers have announced plans for a meta-analysis to investigate the effects of peer support on fear of disease progression (FoP) in patients with glioma. Glioma is a type of brain tumor that often causes significant emotional distress, including fear that the disease will worsen. The study will also look at secondary outcomes such as fatigue, depression, and anxiety.

The protocol for this systematic review and meta-analysis has been published, but no results are available yet. The researchers will search for studies that compare glioma patients who receive peer support with those who do not. Peer support involves connecting patients with others who have similar experiences, which may help them cope better.

This research is important because fear of disease progression can greatly affect quality of life. If peer support is found to be effective, it could become a low-cost, accessible way to help glioma patients manage their fears. However, since this is just a protocol, it will be some time before we know the actual findings.

What this means for you:
This protocol outlines a future meta-analysis on peer support for glioma patients; results are pending.

Common questions

What is this study about?

This is a plan for a systematic review and meta-analysis that will look at whether peer support helps reduce fear of disease progression in people with glioma. No results are available yet.

Does peer support help with fear of cancer progression?

The study is only a protocol, so there are no findings yet. It is not known if peer support is effective for fear of progression in glioma patients.

When will the results be available?

The researchers have not provided a timeline. The study is still in the planning stage, and results will not be available until the review is completed.

Study Details

Study typeMeta analysis
EvidenceLevel 1
PublishedJul 2026
View Original Abstract ↓
BackgroundDue to the characteristics of high recurrence rate, high disability rate and high mortality rate, glioma patients will have a high level of fear of disease progression (FoP), which further affects the happiness and quality of life of patients. Peer support is a powerful, sustained and affordable intervention that plays a positive role in many diseases by providing patients with the emotional, social and practical assistance necessary to manage their disease and maintain their health through a variety of intervention forms. Therefore, peer support may be an effective way to reduce FoP and improve mental health in patients with glioma.MethodsEight databases (PubMed, Embase, Cochrane Library, CNKI, PsycNET, MEDLINE, Psychology & Behavioral Sciences Collection and Web of Science) will be used to select eligible studies that were published from inception to March, 2026. The eligible studies will be screened, extracted and then the methodological quality will be evaluated independently by two reviewers. RevMan version 5.3 software and Stata version 18.0 software will be used for meta-analysis.ConclusionThe results of this meta-analysis will provide evidence for the effectiveness of peer support in patients with glioma. In the future, this study will provide theoretical basis for developing individualized peer support intervention programs to improve adverse health emotions such as FoP, fatigue, depression and anxiety in glioma patients.Systematic review registrationPROSPERO CRD 42024556385.
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