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Case report and literature review on pulmonary thromboembolism after vertebroplasty1. HEADLINE

AI-generated summary of the cited source, checked by automated accuracy review. How we work

Key Takeaway
Note that bone cement leakage after vertebroplasty can cause acute massive pulmonary thromboembolism within 2 weeks.

This source is a case report and literature review focusing on pulmonary thromboembolism secondary to bone cement leakage following percutaneous vertebroplasty. The scope includes a single patient who developed acute massive pulmonary thromboembolism within 2 weeks after the procedure. The authors note that bone cement leakage into the heart and pulmonary arteries can induce this serious adverse event.

The main results indicate that patient symptoms improved immediately, but a cord-like foreign body was still present at the 3-month follow-up. The review does not report specific adverse event rates or statistical data beyond this single case. Safety information regarding tolerability and discontinuations is not reported in this source.

The practice relevance is limited by the retrospective nature of the analysis and the small sample size of one case. The authors do not provide pooled effect sizes or confidence intervals because the evidence is observational and based on a single report. Clinicians should recognize that while symptoms may resolve quickly, the foreign body may persist.

Rare Cement Leak Triggers Massive Clots In Heart And Lungs

2. AT-A-GLANCE

  • Rare cement leak blocks heart and lung arteries.
  • Patients undergoing spine fracture surgery face this risk.
  • Cement may remain in body despite symptom relief.

3. QUICK TAKE A rare complication sees bone cement from spine surgery travel to the heart and cause dangerous lung clots in patients.

4. SEO TITLE Bone Cement Leak Causes Heart Clots After Spine Surgery

5. SEO DESCRIPTION Bone cement used in spine surgery can rarely leak into the heart and cause dangerous lung clots in patients needing fracture stabilization procedures.

6. ARTICLE BODY

Imagine waking up after spine surgery and struggling to breathe. It is a scary thought for anyone facing a fracture repair procedure.

Most people recover well from these procedures without major issues. But rare complications can happen during the healing process.

A new report highlights a specific risk involving bone cement. This material helps stabilize broken bones in the spine.

Usually the cement stays exactly where the doctor places it. Sometimes it can leak into nearby blood vessels instead.

When Spine Surgery Cement Moves

This leakage is extremely uncommon but very serious for the patient. It can travel from the spine into the heart.

From there it moves into the arteries that carry blood to the lungs. This blockage causes a massive clot.

Doctors call this condition pulmonary thromboembolism. It stops blood from reaching the lungs efficiently.

Why does this happen during a routine procedure? The cement is liquid when injected and hardens over time.

How Cement Travels To The Heart

Think of the cement like water flowing through a pipe. If the pipe has a crack it can escape.

In the spine there are small veins that connect to the heart. The cement can follow this path.

Once inside the heart it forms a cord-like shape. This shape blocks the flow of blood to the lungs.

The patient in this report felt symptoms within two weeks. They had trouble breathing and chest pain.

Doctors used special scans to find the problem. They saw a shadow in the lung arteries.

What Doctors Found In The Scan

The scan showed the cement started at the spine. It moved through veins into the right side of the heart.

It then extended into the main arteries of the lungs. This created a blockage that needed immediate action.

Surgeons removed the clots using aggressive therapy. They also gave medicine to prevent new clots.

The patient felt better right after the surgery. Their breathing improved significantly in the hospital.

This does not mean this treatment is available yet.

However the cement itself did not disappear completely. It remained in the body for three months.

This shows that fixing the clot does not remove the source. The foreign material stays behind.

Why The Cement Did Not Leave

Experts say this case is very rare. Most patients do not experience this kind of complication.

Still doctors need to be aware of the risk. They monitor patients closely after the procedure.

If you have spine surgery you should know the signs. Watch for sudden trouble breathing or chest pain.

Talk to your surgeon about your specific risks. They can explain how they prevent leaks during the operation.

This report is just one case study. It does not prove this happens to everyone.

We need more research to understand the frequency. Larger studies will help doctors predict the danger better.

Approval for new treatments takes time and testing. Patients should wait for official medical guidance.

Future trials will look at how to stop the leak. They might find better ways to inject the cement.

Study Details

Study typeSystematic review
EvidenceLevel 1
PublishedApr 2026
View Original Abstract ↓
BackgroundBone cement leakage is a complication of percutaneous vertebroplasty. However, the cement can extremely rarely extravasate into the heart and pulmonary arteries and form cord-like foreign bodies, inducing acute massive pulmonary thromboembolism.Case presentationWe present a case of a patient who developed acute massive pulmonary thromboembolism within 2 weeks after PVP, resulting from bone cement leakage into the heart and pulmonary arteries with subsequent thrombosis. Lower extremity vascular ultrasonography ruled out the possibility of thrombus detachment secondary to deep venous thrombosis. Computed tomography pulmonary angiography revealed strip-shaped hypodense filling defects in the main trunks and some branch arteries of the bilateral pulmonary arteries and a cord-like hyperdense shadow. Combined computed tomography pulmonary angiography and three-dimensional reconstruction of the thoracic spine showed that the cord-like foreign body originated from the 8th thoracic vertebra, entered the azygos vein through the vertebral venous system, then continuously traversed the superior vena cava and right cardiac system, and finally extended to the main trunk of the right pulmonary artery, as well as the branches of both pulmonary arteries. Following aggressive surgical thrombolysis and postoperative anticoagulant therapy, the patient’s symptoms immediately improved. Nevertheless, computed tomography pulmonary angiography still showed the cord-like foreign body after 3 months.ConclusionMoreover, this report retrospectively analyzes the diagnostic and therapeutic strategies for pulmonary thromboembolism secondary to bone cement leakage after percutaneous vertebroplasty through a literature review.
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