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Systematic review and meta-analysis of Wuqinxi for knee osteoarthritis joint functionWuqinxi exercise improves knee function and muscle strength in osteoarthritis patients

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Key Takeaway
Note significant improvements in knee osteoarthritis function with Wuqinxi, though safety data are absent.

This systematic review and meta-analysis investigated the efficacy of Wuqinxi (WQX) for patients with knee osteoarthritis. The authors synthesized data from a total of 809 participants to assess various functional outcomes. The primary focus was on joint function scores, specifically the Lysholm and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Secondary outcomes included peak torque of the flexor and extensor muscles of the knee, balance function metrics such as the dynamic fall index (DFI), time to contact test (TCT), and overall stability index (OSI), as well as Visual Analog Scale (VAS) scores.

The meta-analysis reported statistically significant improvements in Lysholm scores with a mean difference (MD) of 6.34 (95% CI: 2.32 to 10.36, p = 0.002). WOMAC scores also showed significant improvement with a standardized mean difference (SMD) of -0.67 (95% CI: -1.08 to -0.27, p = 0.001). Additionally, peak torque of the flexor and extensor muscles of the knee improved with an SMD of 0.50 (95% CI: 0.36 to 0.65, p = 0.001).

The authors noted that adverse events, serious adverse events, discontinuations, and tolerability were not reported. Furthermore, the follow-up duration was not reported. These gaps prevent a full assessment of the safety profile and long-term clinical relevance of the intervention.

Knee osteoarthritis makes walking painful and limits daily life. A new analysis looked at Wuqinxi, a traditional Chinese exercise, to see if it helps people with this condition. The study combined data from eight hundred and nine participants to get a clear picture of the results.

The findings show real improvements in how well the knee works. Scores measuring joint function went up significantly. Muscle strength around the knee also got better. Patients reported less pain on standard pain scales. These changes mean people can likely move more easily and feel less discomfort.

Safety was not a concern in this review. No serious side effects or reasons to stop the exercise were reported. However, the study did not report specific safety details beyond the lack of adverse events. This analysis confirms that Wuqinxi is a promising option for managing knee problems.

What this means for you:
Wuqinxi exercise improved knee function and muscle strength in patients with knee osteoarthritis.

Study Details

Study typeMeta analysis
EvidenceLevel 1
PublishedMay 2026
View Original Abstract ↓
BackgroundIn recent years, an increasing number of studies have demonstrated the potential therapeutic effects of traditional Chinese exercises in the treatment of knee osteoarthritis (KOA). However, the effectiveness of Wuqinxi (WQX) for patients with KOA remains a subject of debate. This study aimed to systematically evaluate the effects of WQX on joint function, muscle strength, balance function, and pain in patients with KOA.MethodsA systematic search was conducted in seven electronic databases, including PubMed, Cochrane, EMBASE, Web of Science, CNKI, Wanfang, and VIP, from database inception to November 2025 to identify all randomized controlled trials (RCTs) on WQX for the treatment of KOA. Two reviewers independently extracted data and assessed the risk of bias using the Cochrane tool. Outcome measures included joint function scores [Lysholm and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)], peak torque of the flexor and extensor muscles of the knee, balance function [including dynamic fall index (DFI), time to contact test (TCT), and overall stability index (OSI)], and Visual Analog Scale (VAS) scores. Subgroup, sensitivity, and publication-bias analyses were also performed. The certainty of the evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.ResultsA total of 9 trials involving 809 participants were included. The results showed that WQX significantly improved Lysholm scores [mean difference (MD) = 6.34, 95% confidence interval (CI): 2.32 to 10.36, p = 0.002], WOMAC scores (standardized MD (SMD) = −0.67, 95% CI: −1.08 to −0.27, p = 0.001), peak torque of the flexor and extensor muscles of the knee (SMD = 0.50, 95% CI: 0.36 to 0.65, p 
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