Maternal free vitamin D linked to offspring asthma risk
Free Vitamin D in Pregnancy May Lower Child Asthma Risk
Maternal free 25OHD during pregnancy may better predict offspring asthma risk than total vitamin D, especially in mothers with asthma.
Mothers with asthma who had higher free vitamin D levels during pregnancy were less likely to have a child with asthma or wheeze by age 3.
Artificial intelligence as a mechanistic microscope and digital twin in colorectal cancer faces generalizability and regulatory validation limitations
Artificial intelligence acts as a digital microscope for colorectal cancer patients
This narrative review discusses the use of artificial intelligence as a mechanistic microscope and digital twin for patients with colorectal…
A review explores how artificial intelligence could help doctors see colorectal cancer better, though more testing is needed before patients…
Global allergy research grows 7.59% annually but risk-factor studies dominate, burden data scarce
Allergy research grows 7.6% yearly but misses key disease burden data
A systematic bibliometric and evidence-mapping review of 1,543 publications on allergic disorder epidemiology from 2016 to 2025 found a 7.59…
Allergy research is booming, but a new review finds most studies focus on risk factors, not the real-world burden of disease.
NF-κB signaling integrates mechanical stress and immunity in osteoarthritis joint degeneration
New review reveals how inflammation drives osteoarthritis joint damage
This narrative review synthesizes evidence on NF-κB signaling as a central hub integrating mechanical stress, innate immunity, and metabolic…
A new review explains how mechanical stress, immune signals, and metabolism combine to drive osteoarthritis, pointing to smarter treatments.
Gut eosinophils emerge as central regulators of intestinal homeostasis and immunity
Gut immune cells may be key to intestinal health and disease
This narrative review synthesizes emerging evidence positioning gastrointestinal eosinophils as central regulators of intestinal homeostasis…
New research suggests gut eosinophils are not just allergy cells but central players in immunity, repair, and even cancer defense.
CAR technology for autoimmune disorders, infectious diseases, fibrotic lesions, inflammatory bowel disease, and type 1 diabetes is reviewed
Chimeric antigen receptor technology may help treat autoimmune disorders and other conditions
This narrative review discusses the application of chimeric antigen receptor (CAR) technology across autoimmune disorders, infectious diseas…
A narrative review suggests chimeric antigen receptor technology could be useful for treating autoimmune disorders, infectious diseases, and…
Endothelial ferroptosis blockade targets ischemic stroke and neurodegenerative conditions in brain microvascular endothelial cells
Ferroptosis blockade risks in brain microvascular endothelial cells need evaluation
This narrative review discusses endothelial ferroptosis blockade as a potential strategy for ischemic stroke, neurodegenerative conditions, …
A review suggests blocking ferroptosis in brain cells requires more study before use in stroke or neurodegenerative disease patients.
Higher pan-immune-inflammation value linked to worse outcomes after PCI for ACS
High inflammation scores predict worse heart outcomes in patients with acute coronary syndrome
This systematic review and meta-analysis of 18,715 adults with acute coronary syndrome undergoing PCI found that higher pan-immune-inflammat…
A new analysis shows higher inflammation markers predict death and heart failure in adults with acute coronary syndrome undergoing heart pro…
Immunotherapy and metabolic-targeted drug combination shows promise for osteosarcoma treatment
Combining immunotherapy with metabolic drugs may help treat osteosarcoma better
This narrative review explores combining immunotherapy with metabolic-targeted drugs for osteosarcoma, focusing on metabolic reprogramming i…
Doctors are looking at mixing immune system treatments with drugs that change how cells use energy. This new approach could help fight back …
1 514 781 patients shows methylisothiazolinone allergy prevalence is 5.48% in dermatitis cases
Large review shows contact allergy to isothiazolinones affects many dermatitis patients
This systematic review and meta-analysis examined contact allergy prevalence to isothiazolinones in 1 514 781 dermatitis patients from 2000 …
A massive review of over 1.5 million patients found that contact allergy to isothiazolinones is common in dermatitis cases, with methylisoth…
Tumor occurrence was 25% in patients with anti-mGluR5 autoimmune encephalitis, higher in Western than Chinese patients
Tumors appear in one quarter of patients with this rare brain inflammation
This systematic review and analysis examined 60 patients with anti-mGluR5 autoimmune encephalitis. The authors compared MRI-negative versus …
A review of 60 patients found tumors in 25 percent of cases, with rates much higher in Western regions than in China.
Modulation of neutrophil function and death in critically ill patients with sepsis is discussed in this narrative review
Review discusses neutrophil modulation in sepsis for critically ill patients
This narrative review discusses modulation of neutrophil function and death in critically ill patients with sepsis. The authors synthesize c…
This narrative review explores how changing neutrophil function might affect sepsis outcomes in critically ill patients, though no specific …