Endovascular Therapy Offers Less Invasive Option for Blood Blister-Like Aneurysms
Clotting Or Coiling: New Review Weighs Aneurysm Options
This narrative review compares surgical and endovascular approaches for intracranial blood blister-like aneurysms. Surgical treatment is ass…
A new review compares surgery and less invasive options for rare blister-like aneurysms, where treatment choices remain controversial.
Sequential BTK inhibitor therapy maintains hematological and renal stability in Waldenström macroglobulinemia with renal dysfunction
New treatment approach shows promise for rare blood cancer patients
This case report and systematic review describes a patient with Waldenström macroglobulinemia and light-chain proximal tubulopathy treated w…
A new treatment plan for a rare blood cancer helped a patient maintain stable kidney function and a steady blood response.
Host-directed therapy including metformin and statins may modulate immune response in tuberculosis patients
Repurposed Drugs Like Metformin May Help Fight Tuberculosis
This narrative review explores host-directed therapy (HDT) as an adjunctive strategy to modulate immune responses and limit immunopathology …
New research explores how host-directed therapies, including common drugs like metformin and statins, could help the body fight tuberculosis…
CAR-engineered cell therapy remains an experimental platform and lacks clinical validation for asthma treatment
CAR Cell Therapy for Asthma Still Experimental, Review Finds
This narrative review examines the role of chimeric antigen receptor (CAR)-engineered cell therapy in the context of asthma. The authors con…
A new review says CAR cell therapy for asthma is promising but still experimental, with no clinical validation yet.
Single-cell omics identifies TREM2+ macrophages and LAG-3/TIM-3 axis as actionable targets in gynecological cancers
Single-Cell Analysis Identifies New Targets for Gynecological Cancers
This systematic review utilizes functional single-cell omics to analyze the microenvironments of ovarian, cervical, and endometrial cancers.…
New research using single-cell technology identifies specific immune barriers and potential targets for ovarian, cervical, and endometrial c…
Single-cell and spatial multi-omics identify structured malignant cell states and immunosuppressive niches in glioblastoma
New mapping tools reveal hidden patterns in glioblastoma tumors
This narrative review explores how single-cell and spatial multi-omics technologies map the architecture of the glioblastoma tumor microenvi…
New mapping technologies show how glioblastoma cells organize themselves into specific zones, which could help shape future vaccine treatmen…
CSF metagenomic next-generation sequencing identifies microbial nucleic acids in culture-negative anaerobic CNS infections
New method helps identify germs in hard to treat brain infections
This narrative review evaluates the utility of cerebrospinal fluid metagenomic next-generation sequencing (mNGS) for detecting anaerobic CNS…
Doctors are finding new ways to identify hidden germs in the brain using advanced genetic sequencing to help treat complex infections.
Vigorous activity and regular exercise are associated with lower psoriasis prevalence in patients with psoriasis
Regular Exercise May Help Manage Psoriasis and Joint Pain
This umbrella review synthesizes evidence on exercise, physical activity, and fitness for patients with psoriasis and psoriatic arthritis. T…
Regular physical activity and vigorous exercise may be linked to lower psoriasis prevalence and improved symptoms for those with psoriatic a…
Type I/III interferon signaling is the most reproducible molecular program in anti-MDA5+ DM-ILD
Molecular Programs Help Map Lung Risks in Dermatomyositis Patients
This scoping review of 95 sources maps molecular programs and prediction models for anti-MDA5-positive dermatomyositis with interstitial lun…
New research maps out the molecular signals and imaging data that may help doctors better predict and track lung health in patients with der…
FDA Approves Rhapsido for Chronic Spontaneous Urticaria Inadequately Controlled by H1 Antihistamines
FDA Approves Rhapsido for Adults With Hard-to-Treat Hives
The FDA has approved Rhapsido (no generic name provided in label) for adults with chronic spontaneous urticaria who remain symptomatic despi…
The FDA approved Rhapsido for adults with chronic spontaneous urticaria, a type of ongoing hives, whose symptoms continue despite standard a…
IVMP plus efgartigimod ranked highest for mRS improvement in autoimmune encephalitis network meta-analysis
Comparing Different Treatment Options for Patients with Autoimmune Encephalitis
This network meta-analysis of 1,359 patients evaluated acute-phase immunotherapeutic strategies for autoimmune encephalitis. The study found…
Doctors are looking for the best way to treat brain inflammation. New data compares several common therapies to find the most effective opti…
P-GemOxD with lopinavir/ritonavir ART yields complete metabolic response in HIV-associated ENKTCL
Treatment plan shows success for rare lymphoma in HIV patient
This case report and literature review describes a middle-aged HIV-1 positive man with stage IE extranodal NK/T-cell lymphoma, nasal type, t…
A specific chemotherapy combination and radiation plan successfully treated a rare type of lymphoma in a man living with HIV.