Narrative review explores emerging therapeutic strategies targeting Th17 and Treg balance in systemic lupus erythematosus
Could new drugs restore balance for lupus patients, or is the science still too early?
This narrative review examines emerging therapeutic strategies aimed at restoring the Th17 and Treg balance in patients with systemic lupus …
Doctors are exploring new drugs to restore balance between immune cells in lupus, aiming to stop attacks without shutting down the entire sy…
Surgical resection associated with spontaneous remission in Toxocariasis-linked vasculitis case
A Common Parasite May Be Quietly Triggering Autoimmune Disease
A systematic review of a single case report describes a 45-year-old woman with Toxocariasis-associated small-vessel vasculitis.
A common roundworm infection may trigger serious autoimmune blood vessel inflammation, offering a potential cure for unexplained rashes and …
Aging-related CS dysregulation may correlate with inflammatory conditions in elderly populations
Your Immune System Has a Secret Weapon That Changes With Age
This systematic review examines the potential protective role of aging-related corticosteroid (CS) dysregulation in elderly individuals rega…
As we age, a hidden immune system part flips from defender to dual-role player, potentially helping older adults fight inflammation and memo…
Hereditary alpha-tryptasemia modifies GI disease outcomes in individuals of European ancestry
A Hidden Gene Trait May Explain Your Stubborn Gut Symptoms
This systematic review examined the impact of Hereditary alpha-tryptasemia (HαT) on gastrointestinal conditions in individuals of European a…
A hidden gene trait called HαT may worsen stubborn gut symptoms like bloating and pain even when you follow a strict gluten-free diet.
Systematic review finds intestinal microenvironment abnormalities are more severe in HIV immunological non-responders compared to responders
HIV Treatment Leaves Some Patients Behind. Here's Why
This systematic review evaluated intestinal immune and microbial differences between people living with HIV (PLWH) classified as immunologic…
Some HIV patients stay vulnerable to illness even after years of successful treatment because their damaged gut fails to rebuild immunity.
Male sex and advanced age associated with higher risk of RP-ILD in anti-MDA5 dermatomyositis patients
Some Patients With This Rare Lung-Muscle Disease Face Faster Decline
This systematic review and meta-analysis of 15 studies evaluated factors associated with rapidly progressive interstitial lung disease (RP-I…
Men and older adults with a rare autoimmune lung disease are at higher risk of rapid, life-threatening lung damage, a new review finds.
Prospective cohort study links NETosis markers to postoperative frailty in advanced ovarian cancer patients
Do blood markers predict weakness after ovarian cancer surgery?
This prospective cohort study evaluated 189 advanced ovarian cancer patients to assess neutrophil extracellular trap markers.
Three specific blood markers linked to inflammation can predict weakness in women recovering from advanced ovarian cancer surgery.
Retrospective cohort of 162 HLH patients shows combined therapy improves survival over monotherapy
Study links certain factors to survival in patients with hemophagocytic lymphohistiocytosis
This retrospective cohort study analyzed 162 patients with hemophagocytic lymphohistiocytosis (HLH) diagnosed across four medical centers.
Survival rates for hemophagocytic lymphohistiocytosis patients improved when combined therapy regimens were used instead of single treatment…
Retrospective cohort links IINS and RLR to survival in esophageal cancer surgery patients
New blood markers may help predict survival after esophageal cancer surgery
This retrospective cohort study evaluated 660 esophageal cancer patients who underwent radical surgery.
New blood markers that measure inflammation and immunity outperform standard staging to predict survival after esophageal cancer surgery.
Gene expression programs associated with survival and recurrence in early-stage lung adenocarcinoma patients
Why Your Lung Cancer Risk Is Not The Same As Your Neighbor's
This retrospective cohort study evaluated gene expression programs in early-stage (IA/IB) lung adenocarcinoma patients.
Hidden immune signals in early lung cancer act like a weather forecast, predicting who will stay well and who faces a quick return of the di…
VEXAS Syndrome Clinical Features and Treatment Outcomes in a Chinese Cohort of 16 Patients
Small study links UBA1 gene variants to blood and inflammatory issues in China
This retrospective cohort study of 16 Chinese patients describes main clinical features and treatment responses in VEXAS syndrome.
A specific genetic change called a UBA1 variant was found in 81 percent of patients in China with blood disorders and inflammation affecting…
Severe heat stroke correlates with longer hospital stays and higher oxidative stress markers compared to mild cases
Why Your Body Fights Heat Stroke
This prospective cohort study included 49 patients with heat stroke (34 mild and 15 severe cases) and healthy volunteers.
Severe heat stroke disables a key body defense switch, letting rust damage organs and causing patients to stay in the hospital much longer.