Systematic review identifies dual role of NLRP3 inflammasome in sepsis induced immune dysregulation
NLRP3 activation plays a dual role in sepsis
This systematic review examines the role of NLRP3 inflammasome activation and modulation in sepsis.
A review of research shows that a specific protein complex helps drive both inflammation and immune suppression during sepsis.
Th17/Treg ratios and cytokine levels associated with infection risk after kidney transplantation
Immune cell levels may predict kidney transplant infection risk
This cohort study of 200 kidney transplant recipients examined the relationship between Th17/Treg cells and cytokine levels with post-surgic…
Certain immune cell patterns and protein levels could help doctors predict which kidney transplant recipients are most at risk for infection…
Systematic review and meta-analysis of stem cell therapy for dry eye in Sjögren's syndrome
Stem Cell Therapy Eases Dry Eye in Sjögren’s Syndrome Patients
This systematic review and meta-analysis evaluated stem cell therapy for patients with dry eye syndrome caused by Sjögren's syndrome.
New analysis shows stem cell therapy eases dry eye pain and improves tear flow for people with Sjögren’s syndrome.
Review examines thoracic radiotherapy combined with chemoimmunotherapy for extensive-stage small cell lung cancer patients
Doctors are still figuring out the best way to treat extensive-stage small cell lung cancer
This review examines the use of thoracic radiotherapy combined with chemoimmunotherapy in patients with extensive-stage small cell lung canc…
A review notes that while combining radiation with chemotherapy and immune therapy helps some patients, the best approach is still being stu…
Systematic review outlines theoretical basis for early warning and personalized treatment in IgAVN
New blood tests could replace kidney biopsies for children with IgAVN
This systematic review summarizes current research progress regarding Immunoglobulin A vasculitis nephritis management and diagnosis.
A new review shows blood tests might soon replace painful kidney biopsies for kids with IgAVN
Lanadelumab reduced attacks in Chinese adults with hereditary angioedema over six months
Imagine waking up with severe swelling in your throat. It feels like you cannot breathe. This is what hereditary angioedema feels like for many people
This open-label study evaluated safety and efficacy of subcutaneous lanadelumab in patients with hereditary angioedema in China.
This rare condition causes painful swelling under the skin.
Disitamab vedotin plus PD-1 inhibitor showed high response rates in urothelial carcinoma patients across six centers
New Drug Combo Shows Strong Results for Advanced Bladder Cancer
This retrospective cohort study evaluated disitamab vedotin combined with a PD-1 inhibitor in 132 patients with locally advanced or metastat…
A new drug pairing shrank tumors in 71% of advanced bladder cancer patients, even those with diabetes or kidney problems.
Narrative review discusses Chikungunya virus infection without reporting specific clinical data or outcomes
Chikungunya May Become Chronic Due to Immune System Mistake
This source is a narrative review focusing on Chikungunya virus infection.
Chikungunya can trigger a chain reaction in the immune system that leads to chronic joint pain, new research shows.
Review of engineered exosomes for knee osteoarthritis notes significant limitations and lack of efficacy data
Engineered Exosomes Could Change How We Treat Knee Pain
This narrative review examines the potential of engineered exosomes for treating knee osteoarthritis.
New engineered cell parts show promise for stopping knee arthritis damage in early tests before human trials.
Review discusses translational potential of macrophage-state signatures for atherosclerosis risk stratification and therapeutic targeting
Macrophage states in plaque may help predict heart attack risk
This narrative review explores the translational potential of macrophage-state signatures for risk stratification, molecular imaging, and th…
A review suggests that understanding different immune cell states in artery plaque could improve how doctors assess heart disease risk and g…
Consolidation immunotherapy shows no survival benefit over induction alone in stage III non-small cell lung cancer
Adding immunotherapy after chemo may not help stage III lung cancer
This retrospective cohort study evaluated 196 patients with stage III non-small cell lung cancer across 4 hospitals.
Stage III lung cancer patients saw no clear survival gain when immunotherapy was added after chemo and radiation.
Single-center study finds 42.70% allergen sensitization rate in children in Kashi Prefecture
Kids in Kashi face rising allergy risks year-round
This single-center cross-sectional retrospective study evaluated 2,124 children in Kashi Prefecture, China.
More than 4 in 10 kids in western China show signs of allergy sensitivities, even without symptoms, pointing to hidden risks from dust, pets…