Elevated hs-CRP associates with airflow limitation and PRISm in 335 adult liver transplant recipients
High blood inflammation markers raise risk of poor lung health in liver transplant patients
This cohort study of 335 adult liver transplant recipients found that elevated inflammatory markers, specifically hs-CRP >3 mg/L, were assoc…
High blood inflammation markers may signal worse lung function in liver transplant patients, a link doctors have never studied before.
PD-L1-armored CAR-T followed by allo-HSCT yields 7-year remission in refractory B-cell ALL
New Leukemia Treatment Keeps Adult Patient Cancer Free For Seven Years
This retrospective observational analysis of a single clinical case describes an adult patient with early-relapsed, chemorefractory B-cell a…
A new dual-targeted therapy helped an adult with tough leukemia stay cancer-free for seven years after standard treatments failed.
Narrative review covers adoptive cell therapy modalities for ovarian cancer
Cell therapy could stop ovarian cancer from coming back
This narrative review examines adoptive cell therapy (ACT) modalities, including tumor-infiltrating lymphocytes (TILs), chimeric antigen rec…
New immune cell treatments show promise for fighting ovarian cancer when standard drugs stop working.
Narrative review on ICIs in patients with viral infections and solid tumors
Cancer Immunotherapy Works Differently in Viral Infections
This narrative review synthesizes evidence on immune checkpoint inhibitors in patients with viral infections and solid tumors.
Cancer immunotherapy can still work—and sometimes even control viruses like hepatitis or HIV—but doctors must watch for dangerous flare-ups.
Cadonilimab plus chemotherapy shows 72.5% ORR in 51 patients with cervical cancer
New Cervical Cancer Drug Shrinks Tumors In Early Real World Tests
This prospective observational cohort study enrolled 51 patients with cervical cancer receiving cadonilimab (≥2 cycles) with chemotherapy, w…
A new cervical cancer drug shows promising results in early real-world tests, shrinking tumors for most patients while keeping side effects …
Narrative review suggests adjuvant pembrolizumab benefits selected high-risk renal cell carcinoma patients
Old cancer drugs failed, but one new drug saves high-risk kidney patients today
This narrative review evaluates adjuvant therapies for renal cell carcinoma, including cytokine-based immunotherapy, VEGF-targeted agents, a…
Doctors finally have a powerful new tool to stop kidney cancer from coming back after surgery, but it only works for specific patients.
Comprehensive review of ocular toxicity risks across all currently approved antibody-drug conjugates
Cancer drugs may harm your vision without warning
This comprehensive review synthesizes evidence regarding ocular toxicity associated with all currently approved antibody-drug conjugates (AD…
Popular cancer drugs can hurt your eyes, yet doctors often miss these side effects until vision suffers significantly.
Narrative review explores immunopathological framework for complicated intra-abdominal infection and intra-abdominal sepsis
Abdominal Infections Turn Deadly in Hours — Here’s Why
This narrative review examines the compartment-oriented immunopathological framework as a conceptual alternative to traditionally source con…
A hidden immune switch in the belly can trap infection — or unleash life-threatening sepsis, depending on timing and health
Systematic review on tertiary lymphoid structures in hepatocellular carcinoma
These immune clusters may predict liver cancer treatment success
This systematic review synthesizes evidence on tertiary lymphoid structures in hepatocellular carcinoma.
Tiny immune clusters found near liver tumors could help doctors predict if immunotherapy will save lives before treatment starts.
Efgartigimod improved MG-ADL and QMG scores in 81 Chinese patients with generalized myasthenia gravis
Many Myasthenia Gravis Patients Need Just One Treatment Cycle
This single-center, retrospective analysis evaluated efgartigimod in 81 Chinese patients with generalized myasthenia gravis.
Most patients with myasthenia gravis controlled symptoms after a single treatment cycle, with fewer infusions possible for some.
Combined MSK US and machine learning model improves rheumatoid arthritis disease activity assessment
Combined ultrasound and AI model best predicts rheumatoid arthritis activity
This prospective, two-center diagnostic study in 203 patients with rheumatoid arthritis evaluated a combined model integrating musculoskelet…
A new tool using ultrasound and AI outperforms older methods at spotting active rheumatoid arthritis, helping doctors choose better treatmen…
Pretreatment sTNFR1 and infection predict transplant-associated thrombotic microangiopathy in severe aplastic anemia
A simple blood test may flag a deadly transplant complication before it starts
This prospective nested case–control study evaluated patients with severe aplastic anemia undergoing allogeneic hematopoietic stem cell tran…
A blood marker measured before transplant may flag a deadly complication in severe aplastic anemia patients.