Web-based tool improves phenotype capture for Common Variable Immunodeficiency in UK cohort
New Tool Maps Rare Immune Disease Patterns To Guide Treatment
This cohort study of 526 adults with Common Variable Immunodeficiency implemented a web-based Phenotype Capture Tool with clinician training…
A new tool now maps rare immune disease traits with high accuracy, helping doctors match patients to better treatments.
Meta-analysis shows pharmaceutical care improves asthma and COPD management outcomes in 4173 patients
Pharmacist care improves asthma and COPD control and reduces hospital visits
This meta-analysis evaluated pharmaceutical care interventions versus original treatment only in 4173 asthma or COPD patients.
A review of 4173 patients found that pharmacist care significantly improved inhaler use, medication adherence, and asthma control while lowe…
Systematic review on allergic rhinitis links environmental exposures and microbiome changes
Researchers find environment and microbes shape allergy risk
This systematic review synthesizes evidence on environmental exposures and the microbiome in allergic rhinitis.
Air pollution, early antibiotics, and farm life may change your nasal microbes, raising or lowering allergy risk, a new review suggests.
Systematic review identifies 16 mRNA vaccine antigens for pancreatic cancer immunotherapy
New mRNA vaccine targets show promise for pancreatic cancer treatment
This systematic review evaluates 16 mRNA vaccine candidate antigens for pancreatic cancer.
A review of mRNA vaccine candidates found specific targets that could help fight pancreatic cancer, though challenges remain before patients…
Mini-review explores oxidized mannan-conjugated MOG peptide for multiple sclerosis immunotherapy
New MS Treatment Could Teach Immune System To Stop Attack
This mini-review summarizes preclinical evidence on oxidized mannan-conjugated MOG peptide (OM-MOG35-55) for multiple sclerosis.
A new treatment for multiple sclerosis may teach the immune system to stop attacking nerves without shutting down protection or causing majo…
Narrative review discusses eosinophil abundance associations with lung cancer prognosis and immunotherapy response
High eosinophil counts in lung cancer tumors may signal better responses to immune therapy
This narrative review examines eosinophil abundance in tumor tissues and peripheral blood among lung cancer patients.
Elevated eosinophil counts in lung cancer patients often link to improved responses to immune checkpoint inhibitors, though their exact role…
Systematic review and meta-analysis of ENA seropositivity in ANA-IIF-negative connective tissue disease populations
A Negative ANA Test Can Still Miss Autoimmune Disease, Study Finds
This systematic review and meta-analysis evaluated the frequency of extractable nuclear antigen (ENA) seropositivity among 28,552 ANA-IIF-ne…
A negative ANA test doesn't always rule out autoimmune disease, with 14% of negative cases still showing other key antibodies.
Narrative review outlines miRNA-based strategies and challenges in pancreatic ductal adenocarcinoma management
Tiny RNA tricks could help immunotherapy fight pancreatic cancer
This narrative review examines miRNA-based strategies within the context of pancreatic ductal adenocarcinoma treatment options available tod…
MicroRNAs may help immunotherapy work in hard-to-treat pancreatic cancer by reshaping the tumor environment.
Narrative review explores pattern recognition receptor signaling roles in pediatric otitis media management
Doctors find new immune switches to fight stubborn ear infections
This narrative review examines pattern recognition receptor signaling, including TLRs, NLRs, RLRs, and CLRs, within pediatric otitis media.
Smarter immune targeting could stop recurring ear infections in children without relying on heavy antibiotic use or surgery.
High NEK6 expression linked to poor colorectal cancer prognosis and glycolytic subtype dominance
New Target Found to Stop Colon Cancer From Feeding Itself
This cohort study identified three malignant colorectal cancer subtypes, with the Glycolysis-C1 subtype exhibiting a high-glycolytic state.
A newly mapped cancer sugar pathway reveals NEK6 as a target that could starve colon tumors and improve treatment.
Multimodal fusion model predicts pathological complete response in 262 breast cancer patients receiving neoadjuvant therapy
New MRI and Blood Test Combo Predicts Breast Cancer Treatment Success Early
This cohort study evaluated a multimodal fusion model integrating deep learning features from longitudinal DCE-MRI, peripheral blood inflamm…
A smart mix of early MRI scans and blood markers now predicts if breast cancer treatment will work, helping doctors personalize care sooner.
Retrospective Cohort Finds Elevated NLR and PLR Associated with Complications and Survival in Hepatocellular Carcinoma
Post-surgery blood test predicts liver cancer survival better than surgery type alone
This retrospective multicenter cohort study evaluated 74 hepatocellular carcinoma patients undergoing curative hepatectomy or orthotopic liv…
A simple blood test taken months after liver surgery can predict survival better than knowing just how the operation was done.