Combined NT-proBNP, DLK-1, PSP-D, and PCSK-9 detection shows moderate diagnostic performance for HFpEF.
New blood markers may help diagnose heart failure with preserved ejection fraction more accurately
This prospective biomarker cohort study evaluated 58 HFpEF patients and 30 healthy controls to assess the diagnostic utility of specific bio…
Mixing four blood markers improves heart failure diagnosis accuracy compared to standard tests alone, offering a clearer path to early detec…
Methylene blue arterial perfusion increases lymph node detection in rectal cancer resection patients
Blue Dye Helps Surgeons Find More Cancer Cells
A retrospective cohort study of 120 patients undergoing radical rectal cancer resection found that methylene blue arterial perfusion with he…
A simple blue dye injection helps surgeons find more cancer cells, leading to better treatment plans for people with rectal cancer.
Anemia prevalence is 56.4% in heart failure patients, linked to worse clinical profiles.
Low Iron Could Be Making Heart Failure Worse
A retrospective cohort study of 2,144 adult HF patients in Saudi Arabia found anemia prevalence of 56.4% (95% CI 54.3–58.5%), with moderate …
Low iron is far more common in heart failure than doctors assume, and it tracks closely with how sick the heart actually is.
Predictive model for acute heart failure in STEMI patients after PCI shows high accuracy
New Score Predicts Heart Failure Risk After Heart Attack
A retrospective cohort study of 419 STEMI patients treated with PCI at Maanshan People's Hospital evaluated a predictive model for acute hea…
A new score predicts heart failure risk after heart attack by using blood pressure and lab results to spot danger before symptoms appear.
Geranylgeranylacetone mitigates desmin variant-induced atrial cardiomyopathy mechanisms in vitro
A Hidden Heart Flaw May Explain Some Early Atrial Fibrillation
This preclinical in vitro study evaluated HL-1 atrial cardiomyocytes expressing human desmin wild-type or pathogenic variants (p.S13F, p.N34…
A broken heart protein called desmin can silently damage the upper chambers and spark lifelong rhythm problems, while a potential rescue dru…
Endothelial cell isolation feasible in 43% of ANOCA patients in observational study
Chest Pain With Clear Arteries? Scientists Just Cracked A Key Clue
An observational study of 79 ANOCA patients (84% female, mean age 58 years) found that endothelial cell isolation from catheterization mater…
Scientists have found a way to study the real cells lining the hearts of people who suffer mystery chest pain, opening the door to answers t…
Withdrawn laboratory study identifies gene expression changes in valvular heart disease-associated atrial fibrillation
A withdrawn study on heart rhythm disorders found specific gene changes but offers no current treatment.
A withdrawn laboratory study performed RNA sequencing on PBMCs from 15 patients with valvular heart disease-associated atrial fibrillation a…
A withdrawn study on heart rhythm disorders found specific gene changes but offers no current treatment.
FFR-guided complete revascularization reduces unplanned revascularization in MI patients with multivessel CAD
Complete Heart Repair May Stop Future Emergencies
A meta-analysis of 3,054 patients with myocardial infarction and multivessel coronary artery disease found that FFR-guided complete revascul…
Fixing all blocked heart arteries during surgery may stop future emergencies and unplanned procedures for patients with heart attacks.
Pulsed field ablation shows favorable results for freedom from AF compared to other catheter ablation technologies in patients with atrial fibrillation.
New Heart Rhythm Treatment Outshines Older Methods
This network meta-analysis evaluated catheter ablation technologies in patients with atrial fibrillation. Pulsed field ablation (PFA) demons…
Pulsed field ablation may offer faster, more effective heart rhythm restoration than older methods for adults with atrial fibrillation.
Genetic polymorphisms influence pharmacokinetics and bleeding risk for DOACs in meta-analysis
Your DNA May Explain Why Blood Thinners Work Differently for You
A meta-analysis of 39 studies involving 13,300 patients found that genetic polymorphisms (e.g., CES1, ABCB1) are associated with pharmacokin…
Tiny DNA differences may explain why the same blood thinner protects one person but causes bleeding in another.
Laparoscopic gastrojejunostomy resolved symptoms in a patient with superior mesenteric artery syndrome and duodenal stricture.
Man Vomits After Meals For 30 Years — Then Surgeons Find Two Hidden Problems
This case report and literature review describes a 40-year-old man with superior mesenteric artery syndrome and duodenal bulb–descending ulc…
A simple bypass surgery ended 30 years of daily vomiting for a man whose doctors finally found two hidden blockages in his gut.
Narrative review discusses calcium-modifying balloons for PCI in calcified coronary disease.
Review of calcium-modifying balloons for treating calcified coronary artery disease
This narrative review evaluates the role of calcium-modifying dedicated balloons, including scoring, cutting, and ultra-high-pressure device…
Specialized balloons can effectively treat hardened heart arteries, offering versatile options as first-line or complementary tools during p…