Cohort study identifies predictors for retinopathy in hypertensive pregnancy disorders.
A New Risk Calculator Could Predict Eye Damage in Pregnancy Hypertension
This cohort study analyzed 667 patients with hypertensive disorders of pregnancy to identify predictors for retinopathy. The main finding wa…
A new tool uses routine blood pressure and lab tests to spot pregnant patients at highest risk for sight-threatening eye damage from high bl…
Guideline publication synthesizes evidence for clinical practice recommendations.
The FDA Is Changing How It Decides if New Drugs Work — Here Is Why It Matters
This is a guideline publication that reviews evidence to inform clinical practice. It synthesizes recommendations based on available data, b…
The FDA is adopting a smarter statistical method that uses existing science to speed up approvals for new drugs and biosimilars.
Asundexian added to antiplatelet therapy reduces recurrent stroke risk without increasing major bleeding in high-risk patients.
New drug lowers stroke risk in high-risk patients without increasing bleeding
This phase 3 trial evaluated asundexian added to standard antiplatelet therapy in patients with noncardioembolic ischemic stroke or high-ris…
A new daily pill lowers stroke risk in high-risk patients without increasing bleeding, offering a safer option for preventing clots after a …
Smartwatch monitoring increased new-onset AF detection in elderly patients compared to standard care
Smartwatch monitoring found more new heart rhythm issues in older patients than standard care
This randomized controlled trial enrolled 437 patients aged 65 years or older with elevated stroke risk at secondary care centers in the Net…
Smartwatch monitoring found more new heart rhythm issues in older patients than standard care, potentially changing treatment plans for thos…
Prednisolone plus standard treatment did not significantly reduce coronary-artery lesions in newly diagnosed Kawasaki disease patients.
Adding prednisolone to standard care did not prevent heart damage in Kawasaki disease patients.
This multicenter, open-label, randomized, controlled trial evaluated 3208 participants with newly diagnosed Kawasaki disease in China. The s…
Adding prednisolone to standard care did not prevent heart damage in Kawasaki disease patients, as lesion rates remained nearly the same.
Home-based cardiac rehab yields greater mental health and HRQoL gains in heart failure patients with elevated depression
For heart failure patients with depression, home exercise programs improved mental health and daily life.
This secondary analysis of individual patient data from the REACH-HF randomized trials (263 patients with HFrEF and HFpEF) tested whether el…
For heart failure patients struggling with depression or anxiety, home exercise programs significantly improved their mental health and dail…
Bipolar linear PFA shows similar safety to RFA for CTI ablation in persistent atrial fibrillation
PFA Ablation Matches Old Method With Less Time
This substudy RCT compared bipolar linear pulsed field ablation (PFA) with irrigated radiofrequency ablation (RFA) in 141 patients with pers…
Doctors can treat a specific heart rhythm problem faster with new technology without making it less safe.
PCI Reduces MACE in Nonfrail Patients With CAD and Severe Aortic Stenosis Undergoing TAVR
PCI reduces heart events in nonfrail patients but increases bleeding risk for frail patients.
This randomized controlled trial evaluated percutaneous coronary intervention versus conservative treatment in 407 patients with coronary ar…
Stents cut heart attacks for strong patients with blocked arteries and new valves, but frail patients face higher bleeding risks instead of …
Residual global μQFR assessment associated with 3-year MACE risk in acute coronary syndrome patients
Better Heart Maps Predict Long-Term Survival
This post hoc analysis of a randomized controlled trial evaluated 2,428 acute coronary syndrome patients over 36.0 months. High-risk residua…
A new heart map predicts long-term survival just as well as expensive pressure wires, helping doctors spot high-risk patients after stent pr…
Corrective re-analysis suggests Lp(a) reduction accounts for 57-70% of PCSK9 inhibitor benefit in ASCVD.
Re-analysis suggests most PCSK9 inhibitor benefit comes from lowering Lp(a)
This Phase 3 corrective re-analysis of cardiovascular outcomes trial data in secondary prevention populations with ASCVD evaluated the role …
Researchers re-analyzed data from Phase 3 trials of alirocumab and evolocumab in patients with atherosclerotic cardiovascular disease. They …
Systematic review finds low-certainty evidence against endovascular therapy superiority in vertebral artery stenosis
Stents May Not Stop Strokes in Narrowed Neck Arteries
This systematic review evaluated endovascular therapy versus medical treatment alone in adults with symptomatic vertebral artery stenosis. T…
Stents might not stop strokes in narrowed neck arteries better than medicine alone for people with blocked blood flow to the back of the bra…
POCUS-guided assessments and serial exchange transfusions improved outcomes in a 20-year-old male with sickle cell disease and acute chest syndrome.
Bedside Ultrasound Saves Sickle Cell Lives
This single case report describes a 20-year-old male with HbSS, acute chest syndrome, and acute pulmonary hypertension managed in the ICU. U…
A simple ultrasound at the bedside can tell doctors exactly when a sickle cell patient needs another blood transfusion to save their life.