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Cardiology

566 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
FDA Approves Baxfendy (baxfendy) for Hypertension in Adults Not Adequately Controlled
Cardiology FDA Approval
FDA Approves Baxfendy (baxfendy) for Hypertension in Adults Not Adequately Controlled FDA approves new drug Baxfendy to help lower high blood pressure.
FDA approved Baxfendy, an aldosterone synthase inhibitor, for hypertension in adults not adequately controlled on other agents. It is used i…
The FDA approved Baxfendy (baxfendy) for adults with high blood pressure not controlled by other medicines. It is taken with other blood pre…
Routine prophylactic left atrial appendage closure did not significantly reduce the incidence of the primary composite endpoint
Cardiology RCT
Routine prophylactic left atrial appendage closure did not significantly reduce the incidence of the primary composite endpoint Routine valve closure did not significantly reduce stroke risk in heart surgery patients
In a randomized trial involving 2118 patients undergoing valve repair or replacement, surgical left atrial appendage occlusion failed to low…
A major surgery trial found that closing a heart chamber did not lower stroke risk compared to standard care for patients getting valve repa…
Network meta-analysis of oral Chinese patent medicines for myocardial infarction with heart failure
Cardiology Meta-analysis
Network meta-analysis of oral Chinese patent medicines for myocardial infarction with heart failure Four Chinese medicines show promise for heart failure after heart attack
This network meta-analysis evaluated oral Chinese patent medicines combined with conventional treatment in patients with myocardial infarcti…
A network meta-analysis of 42 trials found four oral Chinese patent medicines improved outcomes when added to standard heart failure treatme…
Systematic review and meta-analysis finds 14.2% 30-day readmission rate after ischemic stroke
Cardiology Meta-analysis
Systematic review and meta-analysis finds 14.2% 30-day readmission rate after ischemic stroke One in seven stroke survivors returns to the hospital within 30 days
This systematic review and meta-analysis of 1,274,267 patients with ischemic stroke found a 30-day unplanned readmission rate of 14.2% (95% …
A massive analysis of over 1.2 million stroke patients shows that one in seven returns to the hospital within 30 days, with infection and he…
Narrative review suggests transcatheter PDA closure improves safety and reduces radiation compared to fluoroscopy
Cardiology Sys. Review
Narrative review suggests transcatheter PDA closure improves safety and reduces radiation compared to fluoroscopy A new way to close a heart hole uses less radiation and takes less time
This narrative review evaluates transcatheter closure of patent ductus arteriosus in patients with this condition. The authors synthesize ev…
A review suggests using a catheter to close a patent ductus arteriosus is safer, uses less radiation, and takes less time than older methods…
Meta-analysis shows PCI before TAVR reduces revascularization but increases bleeding risk in severe aortic stenosis patients with coronary artery disease
Cardiology Meta-analysis
Meta-analysis shows PCI before TAVR reduces revascularization but increases bleeding risk in severe aortic stenosis patients with coronary artery disease Routine PCI before TAVR doesn't save lives, increases bleeding
A meta-analysis of 1,156 patients found that performing PCI before TAVR did not lower mortality but significantly reduced the need for urgen…
For people with severe aortic stenosis and clogged arteries, routine angioplasty before valve replacement didn't reduce deaths but did raise…
Meta-analysis finds higher target-lesion revascularization with Magmaris scaffold vs. DES in ACS
Cardiology Meta-analysis
Meta-analysis finds higher target-lesion revascularization with Magmaris scaffold vs. DES in ACS Magnesium heart scaffold tied to more repeat procedures than standard stents
This meta-analysis of 622 patients compared Magmaris bioresorbable magnesium scaffold with drug-eluting stents in acute coronary syndrome. T…
A new magnesium heart scaffold dissolves over time, but a review finds it may lead to more repeat procedures than standard stents.
Meta-analysis finds systemic lupus erythematosus elevates coronary artery disease risk
Cardiology Meta-analysis
Meta-analysis finds systemic lupus erythematosus elevates coronary artery disease risk People with lupus face higher heart disease risk but genetics show no direct link
This meta-analysis of 2,517,781 individuals from European and East Asian populations found that systemic lupus erythematosus is associated w…
A massive analysis of millions of people found those with lupus have a much higher risk of heart disease, though genetics do not prove a dir…
Residual angina occurs in 42.2% of patients after anatomic complete revascularization for chronic coronary disease
Cardiology RCT
Residual angina occurs in 42.2% of patients after anatomic complete revascularization for chronic coronary disease Residual angina affects over 40% of patients after complete heart artery treatment
This randomized controlled trial evaluated symptomatic patients with chronic coronary disease undergoing invasive management. At six months,…
More than 40% of patients still have chest pain six months after complete heart artery treatment, impacting daily life and medication needs.
Simplified transitional care did not improve guideline adherence in acute heart failure patients over 6 months
Cardiology RCT
Simplified transitional care did not improve guideline adherence in acute heart failure patients over 6 months Simplified care plan shows no overall benefit for heart failure patients
This multicenter randomized clinical trial enrolled 982 patients with acute heart failure. The study evaluated a simplified transitional car…
A new trial found that a simplified discharge plan did not improve medication adherence or symptoms for most heart failure patients, though …
M-TEER reduces heart failure hospitalization risk across all health status levels in mitral regurgitation
Cardiology RCT
M-TEER reduces heart failure hospitalization risk across all health status levels in mitral regurgitation Heart Valve Repair Improves Symptoms in Heart Failure Patients
This RCT subgroup analysis found that mitral transcatheter edge-to-edge repair (M-TEER) reduced the risk of cardiovascular death or heart fa…
A study found that mitral valve repair with MitraClip improved symptoms and reduced hospitalizations in heart failure patients with mitral r…
Prehospital unfractionated heparin bolus improved TIMI flow in STEMI without increasing bleeding risk
Cardiology RCT
Prehospital unfractionated heparin bolus improved TIMI flow in STEMI without increasing bleeding risk Pretreatment with UFH improves artery flow for STEMI patients without extra bleeding risk
This single-center randomized trial evaluated pretreatment with unfractionated heparin in patients with ST-segment-elevation myocardial infa…
Giving unfractionated heparin early at first medical contact improved artery flow in heart attack patients without increasing bleeding risk.