Nanomaterial-based delivery systems offer potential strategies for inducing transplantation tolerance in end-stage organ failure
Nanomaterials May Help Prevent Organ Transplant Rejection
This systematic review synthesizes the properties, mechanisms, and delivery strategies of nanomaterials for inducing transplantation toleran…
New research explores how nanomaterial delivery systems could help patients with organ failure avoid the harsh side effects of traditional d…
Adalimumab significantly improves ACR70 and PASI100 outcomes in patients with psoriatic arthritis
Trial data shows adalimumab helps manage psoriatic arthritis symptoms
This meta-analysis of 5,655 patients with psoriatic arthritis found that adalimumab significantly improved multiple clinical markers includi…
New analysis of over 5,000 patients shows the drug adalimumab significantly improves skin and joint symptoms for those with psoriatic arthri…
SMART and ART show comparable success for early childhood caries, meta-analysis finds
Silver and standard treatments show similar success for children's teeth
This meta-analysis of 398 pediatric participants compared silver modified atraumatic restorative treatment (SMART) with atraumatic restorati…
New data shows that adding silver to a common restorative treatment does not change the clinical success rate for cavities in children's pri…
Electric welding linked to persistent nodular acne in 2 workers, improving away from exposure
Electric welding may be linked to severe cases of acne
This case report from China describes 2 electric welders with persistent nodular acne that improved when away from occupational exposure. Th…
Workers exposed to electric welding and metal fumes developed persistent, severe acne that improved only when they were away from their work…
MDA and ACR20 Best Discriminate Treatment Response in PsA
Specific measures help identify effective treatments for psoriatic arthritis
Meta-analysis of 24 trials finds MDA and ACR20 outperform DAPSA and CPDAI in distinguishing active PsA treatments from placebo.
New data identifies which specific measurement tools best distinguish active treatments from placebos for people with psoriatic arthritis.
Guselkumab improves ACR20 rates to 58.6% and 62.2% in patients with psoriatic arthritis
Trial shows guselkumab helps adults with psoriatic arthritis
This Phase 3b randomized controlled trial evaluated guselkumab in 451 adults with active psoriatic arthritis who had an inadequate response …
A new trial shows that guselkumab significantly improves symptoms for adults with psoriatic arthritis who did not respond well to previous t…
Whole goat milk formula reduces atopic dermatitis incidence in infants with parental history
Goat Milk Formula May Lower Risk of Infant Skin Conditions
This randomized clinical trial of 2132 healthy term infants found no difference in atopic dermatitis incidence between whole goat milk and c…
A clinical trial suggests goat milk formula may reduce atopic dermatitis risk in infants, especially those with a family history of the cond…
Pregnancy-associated melanoma does not independently worsen overall survival when stage is adequately controlled
Pregnancy associated melanoma does not lower overall survival rates
This meta-analysis of observational studies involving 16,467 women found no significant difference in overall survival for patients with pre…
New data shows that a melanoma diagnosis during or shortly after pregnancy does not change the long-term survival outlook for women.
IL-17 inhibitors rank highly for clearance of scalp, nail, and palmoplantar psoriasis
Biologics Show Different Success Rates for Scalp and Nail Psoriasis
This network meta-analysis of 5,946 patients evaluated IL-17/IL-23 axis biologics for difficult-to-treat psoriasis sites. The analysis found…
Different biologics show varying success rates for clearing psoriasis on the scalp, nails, and palms based on a large network analysis.
Delgocitinib and difamilast rank highest among nonsteroidal topical therapies for pediatric atopic dermatitis
New Topical Treatments Show Promise for Children with Eczema
This systematic review and network meta-analysis of 3,994 patients evaluated several novel nonsteroidal topical therapies for pediatric atop…
New nonsteroidal topical treatments like delgocitinib and difamilast show promise as steroid-sparing options for children with atopic dermat…
Multidisciplinary determination of resectability incorporates tumor biology and perioperative systemic therapy in stage III NSCLC
New Guidelines Redefine Surgery Options for Lung Cancer Patients
This clinical guideline addresses the management of stage III non-small cell lung cancer (NSCLC). It advocates for a multidisciplinary appro…
New guidelines suggest that surgery for certain lung cancers should be based on tumor biology and treatment response rather than just anatom…
Single-cell RNA sequencing identifies post-capillary venules and ADAM12+ fibroblasts as potential keloid targets
New research identifies specific cell types driving keloid scar growth
This meta-analysis of transcriptomic data uses single-cell RNA sequencing to identify cellular compositions in keloids across diverse ethnic…
Researchers identified specific blood vessel and skin cell types that may drive the growth of keloids across different ethnicities.