AI pipeline shows substantial agreement with dermatologists for grading atopic dermatitis erythema severity
Can AI help doctors measure eczema severity from photos?
A cross-sectional validation study of 41 AD lesion images found an AI pipeline demonstrated substantial agreement with dermatologist consens…
An AI system graded eczema redness 81% of the time like expert doctors, showing promise for tracking flare-ups from photos.
Retrospective analysis identifies molecular correlates of benefit with encorafenib-based therapy in BRAF-mutant melanoma
Melanoma study finds tumor genetics and immune markers may predict treatment benefit
A retrospective exploratory analysis of the phase III COLUMBUS trial in 921 patients with BRAF V600E/K-mutant advanced melanoma found that s…
Patients with advanced melanoma who have higher tumor mutational burden or signs of immune system activity gain the most survival benefit fr…
Meta-analysis finds oral JAK inhibitors increase HDL and LDL cholesterol levels in patients from RCTs
Common arthritis and skin drugs linked to cholesterol changes, analysis finds
A systematic review and meta-analysis of 13 phase 2 and 3 RCTs involving 5,658 patients found treatment with oral JAK inhibitors (baricitini…
Common arthritis and skin drugs can raise both 'good' and 'bad' cholesterol levels, a review of nearly 4,000 patients shows.
Phase 2 trial: Topical STS01 shows dose-related hair regrowth in mild-moderate alopecia areata
Topical treatment shows hair regrowth in alopecia areata, but quality of life unchanged
A Phase 2 randomized controlled trial in patients with mild to moderate patchy alopecia areata found that topical STS01 (dithranol) produced…
A new topical treatment regrows hair in patchy alopecia, yet patients report no improvement in daily life or feelings even with full regrowt…
Smartphone-based wound measurement shows excellent agreement with planimetry in single-center study
Can your phone measure a wound as well as a doctor?
An open-label, single-center study of 36 patients with chronic wounds compared two smartphone-based measurement methods (Woundtrack semi-aut…
A smartphone app called Woundtrack measures chronic wound sizes just as accurately as the standard doctor method, even for small wounds.
Hair follicle-derived epithelial sheet transplantation shows repigmentation in stable vitiligo patients
Could hair follicles help restore skin color in vitiligo?
In patients with stable vitiligo, transplantation of hair follicle-derived epithelial sheets resulted in skin repigmentation.
Doctors transplanted cells from hair follicles onto vitiligo skin, restoring natural color in patients with stable disease.
Outbreak of Purpureocillium lilacinum fungal skin infections reported at Washington dermatology clinic
What caused a fungal skin infection outbreak at a Washington dermatology clinic?
An outbreak report describes Purpureocillium lilacinum fungal skin infections among patients at a dermatology clinic in Washington.
Health officials investigate a cluster of unusual fungal skin infections at a Washington dermatology clinic caused by a rare fungus.
Chinese APS-1 patients show recurrent AIRE gene deletion, male predominance, and low classic triad incidence
What makes autoimmune syndrome APS-1 different in Chinese patients?
A case report and systematic narrative review of 25 genetically confirmed Chinese APS-1 patients identified a recurrent deletion of AIRE gen…
A new look at 25 genetically confirmed Chinese patients with APS-1 found a specific AIRE gene deletion and a surprising trend where twice as…
Report compares motor vehicle crash death rates across 29 high-income countries
Why do more Americans die in car crashes than people in other wealthy countries?
A descriptive report compared motor vehicle crash death rates in the United States and 28 other high-income countries.
A new report shows the United States has a higher rate of motor vehicle crash deaths than 28 other wealthy nations.
Review analyzes PANoptosis mechanisms and potential treatments for ischemia-reperfusion injury
Review explores a new cell death process in organ damage after blood flow returns
A systematic review analyzed the concept, molecular mechanisms, and potential treatment strategies targeting PANoptosis in ischemia-reperfus…
A new cell death process called PANoptosis drives organ damage when blood flow returns after a blockage, offering fresh targets for future t…
CDC recommends approaches to maintain tuberculin skin testing during expected Aplisol shortage
CDC issues guidance during expected shortage of tuberculosis skin test antigen
The CDC has issued recommendations for maintaining tuberculin skin testing capability during an expected shortage of Aplisol.
Health officials warn of an expected shortage of Aplisol, a key ingredient for tuberculosis skin tests, and are releasing guidance to keep c…
Case report: Initial positive measles IgM tests in two Samoan children were false positives
When a measles test says yes, could it really mean no?
An outbreak report describes two children in American Samoa with rash illness and initial positive measles IgM tests.
A positive measles test for two children in American Samoa turned out to be wrong, revealing other viruses can mimic the disease.