Oral ME3183 shows higher PASI-75 response rates than placebo in moderate to severe plaque psoriasis trial
Could a new pill help clear stubborn psoriasis skin plaques?
A 16-week randomized controlled trial in 132 patients with moderate to severe plaque psoriasis found higher proportions achieving ≥75% PASI …
A new oral pill helped over 60% of patients with moderate to severe psoriasis clear skin plaques significantly better than a placebo in a re…
Network meta-analysis ranks upadacitinib highest for efficacy in moderate-to-severe atopic dermatitis
Study compares eczema medications, finds upadacitinib 30 mg ranked highest for effectiveness
A network meta-analysis of 16,334 adults with moderate-to-severe atopic dermatitis compared approved systemic targeted therapies. Upadacitin…
Upadacitinib 30 mg ranked highest for clearing skin and reducing itch among approved eczema medications in a new analysis of over 16,000 pat…
Placebo effect observed in double-blinded food challenges for dogs with atopic dermatitis
Study finds placebo effect complicates food allergy testing in dogs with skin condition
A randomized, double-blinded, placebo-controlled trial in 12 dogs with atopic dermatitis and adverse food reactions found 91.7% tested posit…
Most dogs with itchy skin reacted to food challenges, but half also reacted to a fake diet, showing the placebo effect makes allergy tests u…
Guselkumab Shows Improvement in Inverse Psoriasis in Single Case Report
Can a psoriasis drug help with a rare, hard-to-treat skin condition?
A case report and literature review describes a 48-year-old male with inverse psoriasis who showed marked improvement in cutaneous lesions a…
A single patient with hard-to-treat inverse psoriasis found marked relief in itching and skin lesions after just three injections of a newer…
PFAS mixture exposure shows positive association with serum total IgE levels in Korean adults
Could everyday chemical exposure be linked to higher allergy markers?
A cross-sectional study of 2,987 Korean adults found a statistically significant positive association between concurrent exposure to a mixtu…
Higher exposure to a mix of five common industrial chemicals was linked to higher allergy markers in nearly 3,000 Korean adults, with one sp…
Arthroscopy-assisted curettage and bone grafting for proximal femur giant cell tumor in a 25-year-old man
Single case report suggests possible approach for treating a rare bone tumor in the hip
A case report describes a 25-year-old man with a giant cell tumor of the proximal femur who underwent arthroscopy-assisted curettage and bon…
Doctors used a small camera to remove a rare hip tumor in one patient, successfully controlling the growth while keeping the joint working n…
Nomogram predicts occupational contact dermatitis risk in Chinese nurses with excellent discrimination
Researchers develop tool to predict skin irritation risk for nurses
An observational cohort study of 2,852 nurses across 40 Chinese hospitals developed and validated a nomogram-based prediction model for occu…
A new tool predicts which nurses face higher skin irritation risk by analyzing nine factors like work habits and sleep duration.
Imiquimod costs substantially less than radiotherapy for lentigo maligna in Australian analysis
Study finds topical treatment for lentigo maligna costs far less than radiotherapy
A phase 3 RCT-based cost analysis of 118 patients with lentigo maligna found imiquimod had dramatically lower healthcare system (US$72.50 vs…
Topical cream costs just $72 per patient versus over $2,600 for radiotherapy when treating lentigo maligna, a sun-damaged skin condition.
Topical PDE4 inhibitors show efficacy in pediatric atopic dermatitis meta-analysis
Could a new cream help kids with eczema find relief faster?
A meta-analysis of 5 RCTs (n=1877) in pediatric mild-to-moderate atopic dermatitis found topical PDE4 inhibitors were associated with higher…
A new class of eczema creams linked to faster relief and better skin clearance in kids, with no increase in side effects compared to standar…
Phase 2a study of bimekizumab in chronic plaque psoriasis reports pharmacokinetics and PASI change at Week 28
Could a new psoriasis treatment work better by targeting two inflammation sources at once?
A Phase 2a, multicenter, randomized, subject- and investigator-blind study investigated the pharmacokinetics, pharmacodynamics, and safety o…
A new psoriasis drug targets two inflammation sources to see if it works better for thick, scaly skin patches in adults.
Phase 3 trial of low-dose IL-2 versus placebo for severe alopecia areata completed in 44 patients
Phase 3 trial tests low-dose IL-2 for severe alopecia areata, results pending
A Phase 3, prospective, randomized, double-blind, multicenter trial compared low-dose IL-2 to placebo in 44 patients with severe alopecia ar…
A major late-stage trial testing low-dose IL-2 for severe alopecia areata has finished, but results on hair regrowth are not yet available.
Phase 2 study of lifileucel TIL therapy in 220 patients with metastatic melanoma
Can a patient's own immune cells be turned into a treatment for advanced melanoma?
A prospective, multicenter, phase 2 interventional study evaluated lifileucel (autologous tumor-infiltrating lymphocytes, LN-144) infusion a…
A new treatment uses a patient's own immune cells to fight advanced melanoma, but results from the mid-stage trial are not yet available.