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Dermatology

103 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Phase 2a study of bimekizumab in chronic plaque psoriasis reports pharmacokinetics and PASI change at Week 28
Dermatology Phase II
Phase 2a study of bimekizumab in chronic plaque psoriasis reports pharmacokinetics and PASI change at Week 28 Could a new psoriasis treatment work better by targeting two inflammation sources at once?
A Phase 2a, multicenter, randomized, subject- and investigator-blind study investigated the pharmacokinetics, pharmacodynamics, and safety o…
A new psoriasis drug targets two inflammation sources to see if it works better for thick, scaly skin patches in adults.
Phase 3 trial of low-dose IL-2 versus placebo for severe alopecia areata completed in 44 patients
Dermatology Phase III
Phase 3 trial of low-dose IL-2 versus placebo for severe alopecia areata completed in 44 patients Phase 3 trial tests low-dose IL-2 for severe alopecia areata, results pending
A Phase 3, prospective, randomized, double-blind, multicenter trial compared low-dose IL-2 to placebo in 44 patients with severe alopecia ar…
A major late-stage trial testing low-dose IL-2 for severe alopecia areata has finished, but results on hair regrowth are not yet available.
Phase 2 study of lifileucel TIL therapy in 220 patients with metastatic melanoma
Dermatology Phase II
Phase 2 study of lifileucel TIL therapy in 220 patients with metastatic melanoma Can a patient's own immune cells be turned into a treatment for advanced melanoma?
A prospective, multicenter, phase 2 interventional study evaluated lifileucel (autologous tumor-infiltrating lymphocytes, LN-144) infusion a…
A new treatment uses a patient's own immune cells to fight advanced melanoma, but results from the mid-stage trial are not yet available.
Phase II trial compares IMCgp100 vs investigator choice in advanced uveal melanoma
Dermatology Phase II
Phase II trial compares IMCgp100 vs investigator choice in advanced uveal melanoma Can a new drug help people with a rare eye cancer live longer?
This Phase II study evaluated IMCgp100 versus investigator's choice (dacarbazine, ipilimumab, or pembrolizumab) in HLA-A*0201 positive adult…
A new drug for advanced eye cancer is being compared to standard treatments to see if it helps patients with a specific genetic marker live …
Phase 3 trial of bimekizumab versus placebo in 435 adults with moderate to severe plaque psoriasis
Dermatology Phase III
Phase 3 trial of bimekizumab versus placebo in 435 adults with moderate to severe plaque psoriasis Can a new drug help people with moderate to severe plaque psoriasis?
A phase 3 randomized controlled trial evaluated bimekizumab versus placebo in 435 adults with moderate to severe chronic plaque psoriasis.
A new drug tested in a large study aims to help clear skin for people with moderate to severe plaque psoriasis.
Phase 3 Study Evaluates Barzolvolimab for Chronic Spontaneous Urticaria
Dermatology Phase III
Phase 3 Study Evaluates Barzolvolimab for Chronic Spontaneous Urticaria Can a new treatment finally help those suffering from chronic hives?
A Phase 3 trial assesses barzolvolimab's efficacy and safety in CSU patients unresponsive to antihistamines.
Adults with chronic hives who don't get relief from standard antihistamines may find new hope in a new treatment called barzolvolimab being …
Sliding Cupping Therapy Matches NBUVB in Psoriasis Severity Reduction at 8 Weeks
Dermatology RCT
Sliding Cupping Therapy Matches NBUVB in Psoriasis Severity Reduction at 8 Weeks Could Sliding Cupping Therapy Be a Game-Changer for Psoriasis Patients?
In a RCT with 60 psoriasis patients, sliding cupping showed similar efficacy to NBUVB in reducing PASI scores by 62.4% vs. 66.9% (P=.526).
Sliding cupping therapy improved psoriasis symptoms just as well as standard light treatment, offering a viable alternative for patients see…