Long-term voglibose use likely caused leukopenia in a 71-year-old man with type 2 diabetes
Switching diabetes drugs reversed low white blood cell counts in a 71-year-old man
This case report describes a 71-year-old male with well-controlled type 2 diabetes who developed leukopenia after long-term voglibose use. W…
A 71-year-old man with type 2 diabetes saw his white blood cell count rise after switching from voglibose to acarbose, suggesting the first …
Bile acid modifications and microbiota interventions show promise for metabolic and digestive diseases in preclinical models
Bile acid and microbiota changes may help treat several diseases
This narrative review examines bile acid modifications, microbiota interventions, and BA-targeted therapies for metabolic, digestive, hepato…
This review explores how changing bile acids and gut bacteria could treat metabolic, digestive, and liver diseases, but most evidence is fro…
Color Doppler ultrasound differentiates Graves' disease from silent thyroiditis in thyrotoxicosis patients
Ultrasound blood flow patterns help distinguish Graves' disease from silent thyroiditis
This single-center prospective observational cohort study of 78 adults with thyrotoxicosis found that color Doppler ultrasound (CDU) with th…
A new study finds that measuring thyroid blood flow with ultrasound can help tell Graves' disease apart from silent thyroiditis, a key diagn…
Metabolic subtypes identify Japanese adults with prediabetes at highest or lowest T2D risk
Japanese adults with prediabetes benefit most from lifestyle changes in one specific metabolic group
This randomized controlled trial enrolled 295 Japanese adults with impaired glucose tolerance in the Japanese Diabetes Prevention Program. P…
A study of 295 Japanese adults found that lifestyle changes work best for those with a specific metabolic pattern. This group had the lowest…
Network meta-analysis reveals optimal aerobic exercise frequency and intensity for improving bone mineral density in osteoporosis patients
Network meta-analysis finds aerobic exercise improves bone density in osteoporosis patients
A comprehensive network meta-analysis of 2,183 participants demonstrates that aerobic exercise significantly boosts bone mineral density acr…
A network meta-analysis of 2,183 participants shows aerobic exercise improves bone density better than control, with specific intensity and …
Pantoprazole exposure linked to insulin autoimmune syndrome in case report
Stopping a stomach acid drug helped a patient with low blood sugar recover
This case report describes a patient with insulin autoimmune syndrome (IAS) temporally associated with pantoprazole exposure. Discontinuatio…
A patient with insulin autoimmune syndrome found relief when doctors stopped a common stomach acid medication, suggesting a possible link be…
Processing methods for ovarian tissue in healthy premenopausal patients were reviewed with no reported outcomes or safety data
Review of methods for handling ovarian tissue from healthy patients
This review examines various processing methods for ovarian tissue collected from healthy premenopausal patients in operating room or transp…
A review looked at ways to process ovarian tissue from healthy women. It found that how the tissue is handled can affect its quality for res…
37 loci linked to gestational diabetes, 7 novel, in large multi-ancestry meta-analysis
Scientists found new genetic links to diabetes during pregnancy in this large study
This meta-analysis of genome-wide association studies across up to 38,305 GDM cases and 776,145 controls identified 37 loci associated with …
A massive study looked at DNA from many people to find genes linked to diabetes in pregnancy. They discovered new genetic markers that help …
FDA Approves Afrezza (insulin human) Inhaled Insulin for Adult Diabetes
FDA approves Afrezza, an inhaled insulin for adults with diabetes.
FDA approved Afrezza, a rapid-acting inhaled human insulin, to improve glycemic control in adults with diabetes. It is administered at the b…
The FDA approved Afrezza, an inhaled insulin powder for adults with diabetes. It is taken at the start of meals using a special inhaler, off…
Ring-augmented gastric bypass shows similar weight loss and safety at one year
Ring-augmented gastric bypass shows similar weight loss at one year
This single-center RCT compared ring-augmented one-anastomosis gastric bypass to conventional bypass in 214 adults. At one year, weight loss…
Adding a silicone ring to gastric bypass didn't improve weight loss or safety at one year in a small trial.
GLP-1RAs show lower risk of serious liver events compared with DPP-4 inhibitors in adults with type 2 diabetes
GLP-1 drugs may lower serious liver risks compared to DPP-4 inhibitors in type 2 diabetes
This systematic review and exploratory meta-analysis evaluated incident cirrhosis or composite serious liver events among adults with type 2…
A new analysis suggests GLP-1 receptor agonists might reduce serious liver events compared to DPP-4 inhibitors for adults with type 2 diabet…
Novel NBAS variants define severe immune dysregulation and poor prognosis in infantile liver failure syndrome type 2
A Chinese girl reveals new genetic causes for severe infant liver failure and immune problems
This case report with systematic review examines NBAS-related disease across 322 previously reported patients. The authors identify novel co…
New genetic findings explain severe liver failure and immune issues in infants, offering hope for earlier diagnosis and care.