GLP-1RA use shows sex-specific pancreatitis and hypotension risks in T2D second-line therapy study
Diabetes drugs work differently in women than men
A retrospective cohort study of 5.15 million adults with type 2 diabetes compared second-line therapies.
Diabetes drugs work differently for women than men, revealing distinct safety and effectiveness outcomes in a massive study of 5 million adu…
First-trimester serum retinol quintiles and pregnancy outcomes in a Chinese prospective cohort
High Vitamin A Might Lower Diabetes Risk But Raise C-Section Odds
A prospective cohort of 1,077 singleton pregnancies in China examined first-trimester serum retinol by quintile.
High vitamin A levels early in pregnancy lower diabetes and low birth weight risks but increase the chance of a C-section.
Preprint paired analysis suggests VSG may improve metabolic and renal markers in youth with T2D and obesity
Surgery Stops Kidney Damage in Obese Teens With Diabetes
This preprint paired analysis examined vertical sleeve gastrectomy (VSG) in youth with type 2 diabetes and obesity over 12 months.
This new study shows that weight-loss surgery can actually heal early signs of kidney stress in teenagers by turning off harmful chemical si…
Meta-analysis finds high prevalence of adverse outcomes in African women with hyperglycaemia in pregnancy
High Sugar in Pregnancy Risks C-Section in Africa
A systematic review and meta-analysis of 9,742 women with hyperglycaemia in pregnancy in Africa found high prevalence rates of caesarean sec…
High blood sugar during pregnancy in Africa significantly raises the risk of needing a C-section, threatening both mother and baby.
Orforglipron shows superior HbA1c reduction versus oral semaglutide in adults with type 2 diabetes on metformin
A New Diabetes Pill Takes On Ozempic's Oral Cousin
A phase 3 RCT of 1698 adults with type 2 diabetes inadequately controlled on metformin found that once-daily oral orforglipron (12 mg or 36 …
A new once-daily diabetes pill called orforglipron lowered blood sugar better than oral semaglutide in a major head-to-head trial, but at th…
L-citrulline with HIIT alters specific microRNAs in obese older adults
How 12 Weeks of Hard Exercise Changes the Molecular Machinery of Aging Muscle
A secondary exploratory analysis of a double-blind randomized trial in 68 obese older adults found that 12-week HIIT with L-citrulline suppl…
A 12-week high-intensity interval training program produced measurable molecular changes in older adults' muscles — and a natural supplement…
Anakinra reduces inflammatory markers in prediabetes but shows no metabolic improvements in RCT
Two anakinra injections changed blood markers in people with prediabetes
A randomized controlled trial in individuals with prediabetes found that two injections of anakinra significantly reduced total leucocyte co…
Two anakinra injections quickly lowered inflammation markers in people with prediabetes, though the drug did not yet improve blood sugar con…
Single aerobic exercise bout shows mixed effects on glucose and neuronal insulin signaling in obesity
A Single Workout That Talks to Your Brain
A small RCT in 15 sedentary adults with obesity found a single bout of aerobic exercise at 70% VO₂max showed a trend toward lower glucose AU…
One workout session raised insulin signals in brain particles, offering a clue to how exercise may protect against Alzheimer's over time.
Sugammadex improves diaphragmatic excursion and reduces pulmonary complications in morbidly obese patients
Sugammadex Helps Obese Patients Breathe Easier
A randomized double-blind controlled trial in 104 morbidly obese patients compared sugammadex (2 mg/kg) with neostigmine+atropine.
This new research shows that a specific reversal drug helps morbidly obese patients breathe better and avoid lung issues after surgery.
Risk factors for recurrence in patients undergoing percutaneous endoscopic lumbar discectomy for lumbar disc herniation
Back Surgery Worked — So Why Did the Disc Come Back?
This systematic review and meta-analysis evaluated 14,454 patients undergoing percutaneous endoscopic lumbar discectomy (PELD) for lumbar di…
A large analysis of nearly 15,000 patients identifies who is most likely to need repeat back surgery — and what lifestyle factors make recur…
Circulating spexin levels are significantly lower in patients with type 2 diabetes mellitus compared to controls
The Hormone That Goes Missing When Diabetes Arrives
This systematic review and meta-analysis evaluated circulating spexin levels in 1,122 patients with type 2 diabetes mellitus and 681 control…
A little-known hormone called spexin shows up in much smaller amounts in people with type 2 diabetes, hinting at a possible link scientists …
Cultural dietary patterns linked to lower obesity risk in global meta-analysis
Your Food Habits Are Shaping Your Weight Risk
A meta-analysis of 48 studies across 68 countries found that traditional dietary patterns were associated with a 23% lower obesity risk and …
Sticking to traditional diets lowers obesity risk by 23% compared to Westernized eating, while moving away from home culture raises it.