Conservative oxygen targets show no mortality difference in mechanically ventilated critically ill adults
New Oxygen Rules Save Lives Without Extra Risk in ICU
This systematic review and meta-analysis of 20,447 mechanically ventilated critically ill adults in the ICU found no substantial difference …
ICU teams can safely use less oxygen for ventilated patients, new research shows, potentially reducing harm without raising death risk for m…
Endoscopic Guidance Does Not Reduce Complications in Tracheostomy
At-a-Glance
In a multicenter RCT, endoscopic-guided percutaneous tracheostomy did not lower perioperative complications compared to nonendoscopic guidan…
A major trial found that using a camera to guide a breathing tube surgery in ICU patients offered no safety advantage over the standard proc…
Subprophylactic anti-Xa levels linked to higher venous thromboembolism risk in critically ill adults receiving low-molecular-weight heparin
Low blood clot prevention drug levels linked to higher risk in sick adults
A systematic review and meta-analysis of 7,124 critically ill adults reveals that 47% failed to achieve target anti-Xa levels. Subprophylact…
A large review found that nearly half of critically ill adults did not reach safe drug levels. Those with lower levels faced a much higher c…
Systematic Review of Injury Patterns in Ultimate Frisbee Athletes
New data reveals how to prevent common injuries in Ultimate Frisbee
This systematic review synthesizes injury epidemiology in Ultimate Frisbee athletes. Lower extremity trauma predominates, while upper extrem…
A new review shows how to stop common injuries in Ultimate Frisbee by using better training and smarter gear before they happen.
Early aggressive fluid resuscitation shows no difference in respiratory failure days in severe acute pancreatitis
Early heavy fluids did not help breathing days in severe pancreatitis patients
This secondary analysis of a multicenter randomized controlled trial in 259 patients with predicted severe acute pancreatitis found no signi…
A study of 259 patients found that using large amounts of fluid early on did not improve breathing compared to moderate fluid use. In fact, …
Case report and review highlights ultrasound-guided microwave ablation for metastatic breast cancer in a single patient
Microwave Ablation Controls Breast Metastasis for Three Years
This case report and review of the literature describes ultrasound-guided microwave ablation in a 59-year-old female with metastatic breast …
A single session of microwave ablation kept a breast cancer metastasis under control for three years with no major side effects.
Sepsis survivors face high readmission, mortality, and long-term impairments
Sepsis survivors face high readmission and death rates
A meta-analysis of 76 studies found that sepsis survivors have a 44% readmission rate at 1 year and rising mortality, with persistent cognit…
One year after sepsis, 44% of survivors are readmitted and 15% die within a month.
Meta-analysis shows association between exclusive human milk and reduced mortality in gastroschisis
Exclusive Breast Milk May Lower Death Risk For Gastroschisis Babies
This meta-analysis of 3661 infants with gastroschisis evaluates the impact of exclusive human milk versus formula. The findings suggest an a…
Exclusive breast milk may lower death risk for babies with gastroschisis compared to formula feeds.
Selective decontamination of the digestive tract reduces hospital mortality in mechanically ventilated ICU adults
Selective decontamination lowers death risk for ICU patients on ventilators
This systematic review and meta-analysis evaluated selective decontamination of the digestive tract (SDD) versus standard care or placebo in…
A massive analysis of 32 studies shows selective decontamination of the digestive tract lowers hospital death rates for adults on ventilator…
Continuous glucose monitoring may reduce mortality and hypoglycemia in ICU patients compared to point of care testing
Meta-analysis links continuous glucose monitoring to lower mortality risk in ICU patients
This meta-analysis evaluated continuous glucose monitoring versus point of care blood glucose measurements in ICU patients.
A new analysis suggests continuous glucose monitoring may lower mortality and hypoglycemia in ICU patients, though evidence remains very unc…
Higher Intraoperative Mechanical Power Linked to Impaired Oxygenation and Pulmonary Complications After Orthopedic Surgery
Higher surgical machine power linked to worse lung oxygen levels after orthopedic surgery
This post hoc analysis of a cluster factorial randomized trial included 2,582 patients undergoing orthopedic surgery.
Using more power during orthopedic surgery was linked to lower oxygen levels and more lung complications in patients recovering from these o…
ICU CogHab cognitive rehabilitation feasibility study in ICU survivors with cognitive impairment
Feasibility study tests cognitive rehab for ICU survivors with cognitive impairment
This randomised controlled feasibility study evaluated a cognitive rehabilitation intervention in 83 ICU survivors with cognitive impairment…
A feasibility study found that cognitive rehabilitation can be introduced to ICU survivors, though recruitment and retention remain challeng…