Chelsea Critical Care Physical Assessment tool shows high content validity and excellent inter-rater reliability
New assessment tool shows promise for critically ill patients
This meta-analysis of 27 studies evaluated the measurement properties of the Chelsea Critical Care Physical Assessment (CPAx) in critically …
A new assessment tool provides reliable ways to track physical function and activity levels in patients who are critically ill.
Higher mechanical power correlates with increased mortality in critically ill patients on invasive ventilation
Higher mechanical power linked to higher mortality in critically ill patients
This systematic review and meta-analysis of 34 studies found that higher mechanical power is associated with increased mortality in critical…
Patients on ventilators with high mechanical power levels face a significantly higher risk of death, highlighting the impact of lung stress.
CT-assessed sarcopenia combined with inflammatory markers predicts higher mortality in critically ill and COVID-19 patients
Low muscle mass and inflammation linked to higher COVID-19 mortality
This meta-analysis of 12,347 patients evaluated the prognostic value of CT-assessed sarcopenia combined with laboratory inflammatory markers…
A large review of patient data shows that low muscle mass combined with high inflammation markers may predict worse outcomes for severe COVI…
Minimally invasive pulse wave analysis exceeds 30% error threshold for cardiac output and index
Pulse Wave Analysis Shows High Error in Measuring Cardiac Output
This systematic review and meta-analysis of 92 studies evaluated the accuracy of minimally invasive pulse wave analysis against pulmonary ar…
New analysis shows that pulse wave measurements may not be accurate enough to replace standard methods for monitoring heart function in crit…
Frailty is associated with higher mortality and poorer neurological outcomes in patients with cardiac arrest
Frailty Linked to Higher Mortality Risk in Cardiac Arrest Patients
This meta-analysis of 12 studies analyzed the impact of frailty on outcomes for adult patients experiencing cardiac arrest. The analysis fou…
Patients with cardiac arrest who are also identified as frail face significantly higher risks of death and poorer neurological outcomes.
Base excess shows 85.8% sensitivity and 82.9% specificity for neonatal sepsis diagnosis in meta-analysis
Base Excess Levels May Help Identify Neonatal Sepsis Risk
This meta-analysis evaluated base excess (BE) for diagnosing and prognosing neonatal sepsis. Pooled sensitivity at ≤-5 mEq/L was 85.8% and s…
A new analysis suggests that measuring base excess levels could help doctors identify and predict risks in infants with neonatal sepsis.
Multimodal neuromuscular training reduces ACL injury risk and improves performance in adolescent volleyball players
Multimodal Training May Reduce ACL Injury Risk in Volleyball Players
This narrative review examines the impact of multimodal neuromuscular training on biomechanical risk and athletic performance in adolescent …
A specific type of neuromuscular training may cut ACL injury risks by half for teenage female volleyball players while improving jump height…
Elevated HMGB1 levels correlate with sepsis diagnosis and increased mortality risk in adult patients
High HMGB1 levels linked to sepsis and higher mortality
This meta-analysis of 3,110 patients found that serum or plasma HMGB1 levels are significantly higher in sepsis patients compared to healthy…
Higher levels of the protein HMGB1 in the blood are linked to more severe cases of sepsis and an increased risk of death for patients.
Hypertension-frailty research surges after 2015, led by US, China, Italy in bibliometric analysis
Mapping the Growth of Research on High Blood Pressure and Frailty
A systematic bibliometric analysis of 4,954 publications maps the intellectual landscape of hypertension and frailty research. Publications …
New research shows a massive jump in studies about high blood pressure and frailty since 2015, helping doctors better care for older adults.
Branching-scenario games may improve equity in end-of-life care education through equity-by-design implementation
Branching-scenario games can improve equity in end-of-life care
This mini-review examines the use of branching-scenario games for acute end-of-life care education. The authors suggest these tools can adva…
Interactive branching-scenario games offer a way to train medical staff on providing more equitable and culturally appropriate end-of-life c…
SLE patients have a 2- to 3-fold higher risk of intracerebral hemorrhage compared to non-SLE populations
Lupus Patients Face Higher Risk of Brain Bleeding
This literature review and case report analyze the association between systemic lupus erythematosus (SLE) and intracranial hemorrhage (ICH).…
Patients with systemic lupus erythematosus may face a much higher risk of brain bleeds compared to those without the condition.
Women critically ill adults on EEG have higher intracranial hemorrhage and seizure discharge rates than men
Trial finds women with impaired consciousness have different outcomes
This post hoc analysis of a multicenter randomized trial included 364 critically ill adults requiring electroencephalography. Women showed h…
A trial of critically ill adults found women with impaired consciousness had higher rates of brain bleeding and seizures but similar surviva…