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ENT (Otolaryngology)

101 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
AI-based MRI shows 0.82 AUC for detecting cervical lymph node metastases in oral squamous cell carcinoma
ENT (Otolaryngology) Meta-analysis
AI-based MRI shows 0.82 AUC for detecting cervical lymph node metastases in oral squamous cell carcinoma AI tools help detect lymph node spread in oral cancer
This meta-analysis of 548 patients evaluates AI-based MRI for detecting cervical lymph node metastases in oral squamous cell carcinoma. The …
Artificial intelligence may help doctors better identify if oral cancer has spread to lymph nodes before surgery.
Immune cell-based therapy shows no significant benefits for tumor response or survival in HNSCC trials
ENT (Otolaryngology) Meta-analysis
Immune cell-based therapy shows no significant benefits for tumor response or survival in HNSCC trials Immune cell therapy shows limited promise for head and neck cancer
This meta-analysis of 30 trials involving 953 patients evaluated immune cell-based therapy (ICT) for head and neck squamous cell carcinoma. …
New data on immune cell-based therapies for head and neck cancer shows mixed results and a need for more rigorous testing.
Selective deep lobe parotidectomy is a safe option for benign deep lobe parotid tumours
ENT (Otolaryngology) Meta-analysis
Selective deep lobe parotidectomy is a safe option for benign deep lobe parotid tumours Selective surgery shows low complication rates for deep lobe parotid tumors
This meta-analysis of 299 patients with benign deep lobe parotid tumours found that selective deep lobe parotidectomy is associated with low…
Surgery for deep lobe parotid tumors shows low recurrence rates and manageable risks like temporary facial weakness or ear numbness.
Radioactive iodine does not significantly reduce recurrence in low-risk differentiated thyroid cancer
ENT (Otolaryngology) Meta-analysis
Radioactive iodine does not significantly reduce recurrence in low-risk differentiated thyroid cancer Radioactive Iodine May Not Prevent Recurrence in Low-Risk Thyroid Cancer
This meta-analysis of 5260 patients evaluated the impact of radioactive iodine on recurrence and survival in low-risk differentiated thyroid…
New data suggests that radioactive iodine may not provide a significant benefit for preventing cancer recurrence in patients with low-risk t…
m6A RNA methylation regulates oocyte developmental competence and early embryogenesis through mRNA stability and translation
ENT (Otolaryngology) Sys. Review
m6A RNA methylation regulates oocyte developmental competence and early embryogenesis through mRNA stability and translation RNA methylation plays a key role in early embryo development
This mini-review explores the role of m6A RNA methylation in mammalian oocyte development and early embryogenesis. The authors synthesize ev…
New research highlights how a specific type of RNA methylation helps control gene expression and stability during early pregnancy and embryo…
HearWHO app shows low diagnostic accuracy for hearing loss compared to pure tone audiometry
ENT (Otolaryngology) Sys. Review
HearWHO app shows low diagnostic accuracy for hearing loss compared to pure tone audiometry App based hearing tests show low accuracy in rural clinics
This observational study evaluated the HearWHO app as a tool for hearing screening in a rural Tanzanian clinic. The app demonstrated low sen…
A mobile app designed to test hearing in noisy environments showed low accuracy compared to standard tests in a rural clinic.
FS-LASIK offers customized ablation and rapid rehabilitation for myopia, hyperopia, and presbyopia
ENT (Otolaryngology) Sys. Review
FS-LASIK offers customized ablation and rapid rehabilitation for myopia, hyperopia, and presbyopia New framework helps doctors choose the best vision correction surgery
This mini review examines corneal refractive procedures, specifically focusing on FS-LASIK for patients with myopia, hyperopia, and presbyop…
Choosing the right eye surgery for vision correction depends on your specific needs, from quick recovery to treating age-related vision chan…
Toripalimab plus paclitaxel and cisplatin improves overall survival in advanced esophageal squamous-cell carcinoma
ENT (Otolaryngology) RCT
Toripalimab plus paclitaxel and cisplatin improves overall survival in advanced esophageal squamous-cell carcinoma Trial shows toripalimab improves survival for advanced esophageal cancer
This Phase 3 randomized controlled trial of 514 treatment-naïve patients with advanced esophageal squamous-cell carcinoma found that toripal…
A new combination therapy involving toripalimab and chemotherapy significantly extended survival for patients with advanced esophageal squam…
PD-L1 expression shows potential utility in predicting malignant transformation risk in oral potentially malignant disorders
ENT (Otolaryngology) Meta-analysis
PD-L1 expression shows potential utility in predicting malignant transformation risk in oral potentially malignant disorders PD-L1 expression may help identify risk in oral pre-cancer
This meta-analysis of 613 patients with oral potentially malignant disorders (OPMDs) found a malignant transformation rate of 21.04% (129 ou…
A review of patient data suggests that checking for specific immune markers could help doctors identify which oral tissue changes are more l…
High tumoral PD-L1 expression correlates with increased local invasion and distant metastases in differentiated thyroid cancer
ENT (Otolaryngology) Meta-analysis
High tumoral PD-L1 expression correlates with increased local invasion and distant metastases in differentiated thyroid cancer High PD-L1 levels linked to thyroid cancer spread
This meta-analysis of 12 retrospective studies indicates that high tumoral PD-L1 expression is significantly associated with lymphovascular …
New data shows that high levels of a specific protein can signal if thyroid cancer is more likely to spread locally or to distant parts of t…
Objective testing identifies higher prevalence of olfactory dysfunction in Primary Ciliary Dyskinesia than patient reports
ENT (Otolaryngology) Meta-analysis
Objective testing identifies higher prevalence of olfactory dysfunction in Primary Ciliary Dyskinesia than patient reports More people with Primary Ciliary Dyskinesia have smell loss than expected
This meta-analysis of 865 patients with Primary Ciliary Dyskinesia (PCD) found a pooled prevalence of olfactory dysfunction at 43.4%. Object…
New data shows that many people with Primary Ciliary Dyskinesia have hidden smell issues that they do not notice on their own.
AI and machine learning applications enhance speech intelligibility and engagement for cochlear implant users
ENT (Otolaryngology) Sys. Review
AI and machine learning applications enhance speech intelligibility and engagement for cochlear implant users AI shows promise for cochlear implant users
This narrative review explores AI and ML applications in cochlear implant rehabilitation, including prediction modeling and speech enhanceme…
AI and machine learning may improve speech understanding and therapy access for cochlear implant users, but real-world proof is still needed…