Intraoperative frozen section shows 98.8% specificity but limited sensitivity for detecting malignancy in Bethesda III nodules
Frozen Section Analysis Shows High Specificity for Thyroid Nodules
This systematic review and meta-analysis of 1,069 patients with thyroid nodules evaluates the diagnostic accuracy of intraoperative frozen s…
Intraoperative frozen section tests show high accuracy in identifying cancer in certain thyroid nodules, but results can vary significantly.
Hybrid minimally invasive oesophagectomy associated with lower rates of conduit necrosis, pneumonia, and nerve paralysis
Hybrid minimally invasive surgery shows fewer complications for esophageal cancer
This meta-analysis of 8 studies involving 6053 patients with oesophageal cancer found that hybrid minimally invasive oesophagectomy (HMIE) s…
A large review of surgical data suggests that a hybrid minimally invasive approach may reduce specific risks like pneumonia and nerve damage…
EGFR and TP53 mutations linked to worse survival in sinonasal squamous cell carcinoma
Genetic markers linked to survival in sinonasal squamous cell carcinoma
A meta-analysis of 25 retrospective cohort studies including 1194 patients with sinonasal squamous cell carcinoma found that EGFR and TP53 m…
Specific genetic mutations and protein levels can help doctors predict how patients with certain head and neck cancers will respond to treat…
High tumor mutational burden correlates with improved objective response rate in HNSCC patients
High tumor mutation burden predicts better results in head cancer
This meta-analysis of 1472 patients with head and neck squamous cell carcinoma (HNSCC) found that high tumor mutational burden (TMB) is asso…
A high number of mutations in a tumor may help doctors predict which patients will respond best to immunotherapy.
Endoscopic parotidectomy reduces blood loss and drain output but clinical impact is limited
Endoscopic surgery shows lower blood loss for parotid gland tumors
This meta-analysis of 1188 patients compared endoscopic-assisted or fully endoscopic parotidectomy with conventional open surgery. Endoscopi…
Endoscopic techniques for parotid gland tumors may reduce blood loss and drainage during surgery while offering similar cosmetic results to …
Combination Therapies Improve Progression Free Survival in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Combination therapies show promise for advanced head and neck cancer
This meta-analysis evaluated combination therapies involving targeted agents or immunotherapy with chemotherapy for patients with recurrent …
Combining immunotherapy or targeted drugs with chemotherapy may help patients with advanced head and neck cancer live longer without the dis…
Completion thyroidectomy follows total thyroidectomy for similar operative safety in differentiated thyroid cancer
Less surgery may be safer for thyroid cancer patients
This meta-analysis of 43,362 patients evaluated the surgical safety of completion thyroidectomy (CT) compared to upfront total thyroidectomy…
For some thyroid cancers, a less extensive surgery may be safer with fewer complications.
Postoperative radiotherapy reduces local and peristomal recurrence rates in laryngeal cancer patients with preoperative tracheotomy
Radiotherapy May Lower Recurrence Risk After Laryngectomy for Cancer
This meta-analysis of 4339 patients evaluates the impact of postoperative radiotherapy (PORT) on recurrence rates following total laryngecto…
Postoperative radiotherapy may lower the risk of cancer returning in the throat area for patients who had a tracheotomy before surgery.
Camrelizumab and apatinib show higher response rates and survival in treatment-naive patients with ESCC
Treatment Naive Patients Show Better Survival with Camrelizumab and Apatinib
This meta-analysis evaluates the efficacy of camrelizumab plus apatinib for advanced or metastatic esophageal squamous cell carcinoma. The a…
Patients with advanced esophageal cancer who have not had prior treatment may see better survival rates when using a combination of camreliz…
Zygomatic implants provide high survival rates for maxillary reconstruction in head and neck cancer patients
Zygomatic implants show high survival for head and neck cancer
This systematic review and meta-analysis of 294 patients with extensive maxillary defects found a 97% overall implant survival rate. The ana…
New data shows zygomatic implants have a 97% survival rate, offering a reliable way to restore jaw function after cancer surgery.
Capecitabine significantly improves progression-free survival (HR 0.69) in advanced oesophagogastric adenocarcinoma
Trial shows capecitabine extends disease control for advanced stomach cancer
This Phase II randomized trial of 266 HER2-negative patients with advanced OGA found that maintenance capecitabine significantly improved pr…
A new trial shows that the drug capecitabine can help keep advanced stomach cancer from progressing for longer.
Music therapy cuts delirium risk by half in ICU patients, meta-analysis finds
Music Therapy May Reduce Delirium Risk for ICU Patients
This meta-analysis of 1,552 adult ICU patients found that music therapy significantly reduced delirium incidence (RR=0.49, 95% CI 0.40-0.60)…
Music therapy may help reduce delirium and improve sleep for adults in intensive care units, offering a safe way to support patient well-bei…