GCSF shows survival benefit in alcohol-related hepatitis, but evidence remains uncertain
Trial shows GCSF may improve survival for alcohol-related hepatitis
This systematic review and network meta-analysis compared 24 treatments for alcohol-related hepatitis, with 90-day survival as the primary o…
A new review of 24 treatments suggests a specific drug, GCSF, could help patients survive acute alcohol-related hepatitis.
Prophylactic HIPEC improves peritoneal metastasis-free survival and disease-free survival in locally advanced colorectal cancer
HIPEC treatment shows promise for advanced colorectal cancer patients
This meta-analysis of 2023 cases evaluated prophylactic Hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with locally advanced…
A new analysis suggests that a specific chemotherapy method may help keep cancer from spreading in patients with advanced colorectal cancer.
Hepatectomy plus splenectomy improves overall survival and recurrence-related survival in patients with hepatocellular carcinoma
Splenectomy May Improve Survival for Patients with Liver Cancer
This meta-analysis of 3967 patients with hepatocellular carcinoma and cirrhotic hypersplenism found that hepatectomy plus splenectomy (HS) s…
A review of over 3,900 patients suggests that adding a splenectomy to liver surgery may improve survival rates for those with certain liver …
Higher intrapancreatic fat deposition is associated with greater liver fat excess in Type 2 Diabetes
Liver Fat Levels Linked to Pancreatic Fat in Type 2 Diabetes
This meta-analysis of 2142 participants found significantly higher liver fat content in individuals with Type 2 Diabetes compared to non-dia…
New analysis shows a link between fat in the pancreas and liver fat levels in people living with Type 2 Diabetes.
Germline multigene panel testing identifies pathogenic variants in 15.2% of colorectal cancer patients
Genetic testing reveals common cancer risks in colorectal cancer patients
This meta-analysis evaluates the prevalence of germline mutations in colorectal cancer patients using multigene panel testing. The study fou…
Genetic testing shows that about 15% of colorectal cancer patients carry genes that increase their risk of developing cancer.
RPAD salvage achieves 12-month remission in TAFRO syndrome with autoimmune background
Rare Immune Storm Calmed by Chemo After Other Drugs Fail
Single case report with literature review describes a 59-year-old man with Sjögren's disease and primary biliary cholangitis who developed T…
A man with a rare cytokine storm didn't respond to standard drugs. A four-drug chemo mix put his disease into remission for 12 months.
Total glucosides of paeony may interrupt the gut-liver axis cycle in liver cirrhosis
TGP May Improve Gut Health in Liver Cirrhosis Patients
This narrative review explores how total glucosides of paeony (TGP) may impact liver cirrhosis through the gut-liver axis. The review synthe…
New research explores how a compound called TGP may improve gut health and liver function in people with liver cirrhosis.
Implementation science methods can bridge the 17 year research-practice gap in infant neuromotor development
Closing the 17 year gap in infant physical therapy care
This perspective piece discusses the 17 year delay between evidence discovery and clinical integration for infant neuromotor development. It…
A massive gap exists between finding new medical evidence and actually using it to treat infants with motor delays.
Environmental factors influence oral tissue alterations through oxidative stress, inflammation, and microbial dysbiosis
Environmental Factors Linked to Changes in Oral Tissue Health
This narrative review explores how environmental factors, including smoking and pollutants, impact oral tissue and salivary homeostasis. The…
Pollutants, smoking, and dietary factors are linked to changes in gum health, tooth structure, and the balance of bacteria in your mouth.
Six amino acid metabolism biomarkers distinguish periodontitis from controls in early in silico and tissue validation
New biomarkers may help identify and track gum disease
This guideline-type report describes an in silico and experimental validation study identifying six amino acid metabolism-related biomarkers…
Researchers identified six specific markers in the blood and tissue that could help doctors better detect and monitor periodontitis.
mpMRI markers of liver disease are associated with lower health-related quality of life in MASH
Liver imaging markers linked to lower quality of life
This multinational real-world randomized controlled trial of 802 patients with suspected MASLD/MASH found that patients with MASH reported l…
New research shows that specific liver imaging markers are linked to lower quality of life and higher anxiety in patients with liver disease…
Diverse strategies for biofilm control and caries-risk mitigation show varying success in clear aligner interfaces
New Research Explores How Clear Aligners Impact Dental Caries Risk
This scoping review of 132 reports examines clear aligner interface properties, oral microbial ecology, and biofilm control strategies. Whil…
New research looks at how clear aligners affect oral bacteria and tooth decay, highlighting various ways to manage and reduce risks during t…