SABR in oligometastatic cancer showed median overall survival of 64.6 months in a single-arm phase 2 study.
SABR offers five-year survival hope for patients with limited cancer spread
This single-arm phase 2 trial evaluated stereotactic ablative radiotherapy (SABR) in 380 patients with oligometastatic cancer across six Can…
Patients with few cancer spots lived longer with SABR treatment. Five-year survival reached 58.6 percent in this Canadian study.
Preoperative symbiotic supplementation alters gut microbiota in colorectal cancer patients
Small trial shows symbiotic changes gut bacteria in colorectal cancer patients
This randomized clinical trial in 46 adults undergoing colorectal cancer surgery found that preoperative symbiotic supplementation increased…
A small Brazilian trial found that taking a symbiotic before surgery changed gut bacteria and fatty acid levels in colorectal cancer patient…
SABR shows worse survival in ultracentral pulmonary oligometastases compared to nonultracentral tumors
Tumor location matters: ultracentral spots linked to worse survival in lung metastasis patients
This secondary analysis of the SABR-5 Phase 2 trial evaluated progression-free and overall survival in 41 patients with ultracentral pulmona…
Tumor location matters. Patients with ultracentral lung metastases had shorter survival times than those with nonultracentral spots after ra…
Patient Buddy App reduced avoidable readmissions in cirrhosis inpatients compared to standard of care.
App helps cirrhosis patients avoid hospital readmission
This randomized clinical trial enrolled 464 subjects (232 dyads) with cirrhosis in a multicenter setting. The Patient Buddy App (HIT) signif…
A smartphone app cut avoidable hospital readmissions in half for cirrhosis patients, a new trial shows.
HEV 239 vaccine induces durable humoral and cellular immunity in Bangladeshi women
Hepatitis E vaccine shows durable immunity in women
This longitudinal cohort study in 1480 women aged 16-39 years in Bangladesh found that HEV 239 (Hecolin) vaccination led to significantly hi…
A hepatitis E vaccine kept women protected for up to 3 years, with stronger immune memory than a comparison group.
Five ACLF diagnostic models and prognostic scores identified markedly different proportions of patients at risk of 28-day mortality in a cohort study.
Two new models find the sickest liver patients faster than old tools
This cohort study evaluated five acute-on-chronic liver failure (ACLF) diagnostic models and prognostic scores in 3,370 patients from the CO…
Two new scoring systems find the most dangerous liver failure patients better than older tools, potentially saving lives by catching risk ea…
Systematic review and meta-analysis evaluates ML and DL models for diagnosing MASH and fibrosis
AI models help doctors spot liver disease with high accuracy
This systematic review and meta-analysis of 106 studies assessed machine learning (ML) and deep learning (DL) models for diagnosing metaboli…
New computer tools can diagnose fatty liver disease and scarring with impressive accuracy. This review analyzed data from many studies to se…
Meta-analysis finds Virtual Scale Endoscopy improves colorectal polyp measurement accuracy
Virtual Scale Endoscopy cuts errors in colorectal polyp measurements
This meta-analysis of 6 clinical and 5 preclinical studies (1581 polyps) found that Virtual Scale Endoscopy (VSE) significantly improved mea…
A new analysis shows Virtual Scale Endoscopy improves accuracy and reduces mistakes when measuring colorectal polyps compared to standard vi…
Systematic review and meta-analysis of colorectal cancer screening prevalence in survivors versus general population
Cancer survivors are more likely to get colorectal cancer screening than the general public
This systematic review and meta-analysis examined colorectal cancer screening prevalence across 59 studies involving cancer survivors and th…
A large review of 59 studies found cancer survivors are more likely to get colorectal cancer screening than those without cancer history.
Systematic review finds weak link between atypical antipsychotics and MASLD in youth
Atypical antipsychotics show a small link to liver disease in young patients
This systematic review and meta-analysis of 3 studies examined the association between atypical antipsychotics and metabolic dysfunction-ass…
A review of three studies found a small link between atypical antipsychotics and liver disease in children, but the evidence is limited.
Meta-analysis finds blood biomarkers predict outcomes in anal cancer but need validation
Low blood counts and high inflammation may signal worse survival for anal cancer patients
This systematic review and meta-analysis of 3589 patients with anal squamous cell carcinoma found that elevated neutrophil-to-lymphocyte rat…
For patients with anal cancer, low hemoglobin and high inflammation markers linked to poorer survival in this analysis of nearly 3,600 peopl…
Systematic review shows high rates of fibrosis and cirrhosis in children with Pi*ZZ alpha-1 antitrypsin deficiency.
1 in 4 children with A1AT deficiency develop cirrhosis
This systematic review and meta-analysis examined children with confirmed Pi*ZZ alpha-1 antitrypsin deficiency to assess liver outcomes. The…
New analysis finds 41% of children with A1AT deficiency have liver fibrosis and 17% have cirrhosis.