Gut microbiota alterations linked to anxiety and depression in inflammatory bowel disease patients
Gut bacteria patterns linked to anxiety and depression in inflammatory bowel disease patients
This systematic review of 1,040 patients with inflammatory bowel disease found associations between gut microbiota characteristics and anxie…
A review of 1,040 patients found gut bacteria patterns linked to anxiety and depression in inflammatory bowel disease.
Large meta-analysis identifies 30 new genetic loci for ankylosing spondylitis risk
Scientists found genetic links to ankylosing spondylitis in large health data groups
This meta-analysis of 7,551 AS cases and 1,258,581 controls from three biobanks identified 30 genome-wide significant loci and 64 causal-can…
A big study looked at DNA from many people to find genes linked to ankylosing spondylitis. It found specific spots in our genes that might h…
PFIC null genotype linked to 2.79-fold higher odds of liver transplantation
PFIC null genotype linked to higher liver transplant risk
This meta-analysis of observational studies including 420 PFIC patients found a close association between null genotype and liver transplant…
A meta-analysis of 420 patients found a strong link between a specific genetic variant and the need for liver transplants in progressive fam…
Chemoimmunotherapy improves survival in solid tumors regardless of liver metastasis status
Chemoimmunotherapy helps solid tumor patients, with or without liver metastases
This systematic review and meta-analysis evaluated 25915 patients with solid tumors receiving chemoimmunotherapy versus chemotherapy alone. …
For people with solid tumors, adding immunotherapy to chemo helps survival whether or not cancer has spread to the liver.
Fecal DNA testing improved colorectal cancer screening rates compared to immunochemical testing in primary care
Fecal DNA test boosts colorectal cancer screening rates in community clinics
A pragmatic cluster randomized clinical trial compared mailed fecal immunochemical tests with automated text outreach against mailed fecal D…
A new trial shows that mailing fecal DNA tests with automated text messages increased colorectal cancer screening participation compared to …
FIPS AUC 0.821 outperforms MELD scores for 90-day mortality prediction in TIPS for ascites
New score outperforms MELD for predicting death after TIPS for bleeding
This meta-analysis of 5,180 patients undergoing TIPS for ascites or gastroesophageal bleeding compared MELD-based scores and the FIPS index …
A new scoring system called FIPS may better predict 90-day death risk after TIPS for bleeding than older MELD scores.
Hepatologist-led palliative care matches specialist care for cirrhosis and cancer patients
Trained liver doctors provided care that matched specialists for patients with serious liver disease
A US trial found hepatologist-delivered palliative care noninferior to specialist care for improving quality of life in advanced liver disea…
Patients with advanced liver disease saw similar quality of life improvements when cared for by trained liver doctors versus specialists. Bo…
Endovascular interventions reduce rebleeding risk versus endoscopic cyanoacrylate injection in gastric variceal hemorrhage
Endovascular procedures reduce rebleeding risk for cirrhosis patients compared to injection therapy
This individual patient data meta-analysis compares endovascular interventions with endoscopic cyanoacrylate injection for gastric variceal …
A meta-analysis of 1,240 patients found endovascular procedures significantly lower rebleeding rates than injection therapy, though they car…
Persistent ymrEMVI and ymrTD on post-neoadjuvant MRI predict inferior disease-free and overall survival in rectal cancer patients
Persistent MRI signs linked to worse survival in rectal cancer patients
This systematic review and meta-analysis evaluates prognostic markers in 3932 patients with rectal cancer undergoing neoadjuvant treatment. …
Persistent MRI signs after treatment for rectal cancer are linked to lower survival rates, helping doctors identify patients who may need mo…
Prophylactic clipping after colorectal ESD reduces delayed bleeding risk by 74%
Clipping after colon procedure lowers bleeding risk in adults
This systematic review and meta-analysis of 684 adults found that prophylactic clipping after colorectal endoscopic submucosal dissection si…
A new analysis shows that adding a clip after removing colon polyps significantly lowers the risk of delayed bleeding in adults.
Combining Pentraxin-3 and AFP increases sensitivity to 0.92 for hepatocellular carcinoma diagnosis in chronic liver disease
New blood test helps doctors find liver cancer earlier with better accuracy than old methods alone
This systematic review and meta-analysis evaluated diagnostic markers in adults with chronic liver disease suspected of hepatocellular carci…
A review of 1,179 patients shows a new marker called PTX3 works well for finding liver cancer. Using both PTX3 and AFP together finds more c…
1 in 6 dromedary camels in Africa carries Rift Valley Fever antibodies
Seroprevalence of Rift Valley Fever in African camels varies widely by country
A systematic review and meta-analysis of 7444 dromedary camels across 11 African countries found a pooled RVF seroprevalence of 17.25% (95% …
A meta-analysis of 7,444 camels across 11 African nations found infection rates ranging from 32% to 73%, highlighting significant regional d…