Thymosin alpha1 added to standard therapy improved 90-day transplant-free survival in 73 patients with HBV-related acute-on-chronic liver failure.
Thymosin alpha1 may improve survival in hepatitis B liver failure patients
This open-label randomized controlled trial enrolled 73 patients with hepatitis B virus-related acute-on-chronic liver failure. The study fo…
Adding thymosin alpha1 to standard therapy helped hepatitis B liver failure patients survive longer without needing a transplant.
Laparoscopy-assisted trans-umbilical Meckel's diverticulectomy described in pediatric case series
Can a small keyhole surgery safely fix a rare gut blockage in children?
A case series and literature review of 28 pediatric patients with Meckel's diverticulum complicated by internal hernia described laparoscopy…
A rare gut blockage in children was safely fixed using a small keyhole surgery that kept recovery quick with no complications reported.
Metabolomics analysis reveals distinct B-cell metabolic signatures in IgG4-RD patients compared to healthy controls.
Metabolic changes found in B cells of IgG4-related disease patients
This cohort study analyzed B cells from 32 IgG4-RD patients and 31 healthy controls using UPLC-MS/MS-based metabolomics. Results identified …
A specific panel of 14 chemical markers inside immune cells accurately identifies patients with IgG4-related disease from healthy people.
Serological assays show high concordance for detecting celiac disease-specific autoantibodies in a Tunisian cohort.
Study finds high accuracy for blood tests in detecting celiac disease in Tunisian patients
This cohort study evaluated serological assays, including immunoblot, indirect immunofluorescence test (IIFT), and enzyme-linked immunosorbe…
Blood tests for celiac disease correctly identified all patients in a Tunisian study, proving these simple checks can often replace invasive…
CAM products associated with ACLF in 39.6% of patients with liver injury in retrospective cohort
CAM products linked to liver failure and heavy metal contamination in patients
A retrospective cohort study of 91 consecutive patients with CAM-related adverse events at a South Indian tertiary center found that 39.6% d…
Many complementary medicine products tested contained dangerous heavy metals like cadmium linked to severe liver failure and death in patien…
First-in-human study finds VS-01 generally well tolerated in decompensated cirrhosis with ascites
Early safety study of VS-01 infusion in 12 patients with advanced liver disease
This phase 1b, open-label, non-randomized study in 12 patients with decompensated cirrhosis, ascites, and covert hepatic encephalopathy foun…
A new liver treatment called VS-01 was safe for patients with advanced disease, causing mostly mild stomach issues in an early study of 12 p…
Return to drinking occurs in 22% of alcohol-associated hepatitis patients within 90 days of recovery
Study tracks return to drinking in patients recovering from alcohol-associated hepatitis
A combined RCT and prospective observational analysis of 518 patients with alcohol-associated hepatitis found 21.7% returned to drinking wit…
About one in five patients recovering from alcohol-associated hepatitis return to drinking within 90 days, with higher education levels lowe…
AI web app feedback improves bowel preparation quality in outpatient colonoscopy RCT
Can an AI coach help you get a better colonoscopy prep?
A multicenter RCT of 774 outpatients found that an AI-guided web application providing feedback on rectal effluent images significantly impr…
A new web app using artificial intelligence helped over 770 patients achieve significantly cleaner colonoscopies by analyzing photos of thei…
Dynamic ctDNA monitoring during neoadjuvant chemotherapy identifies high-risk rectal cancer patients
Blood test during chemo may help predict rectal cancer treatment response
A biomarker substudy of a multicenter RCT in 153 patients with low-/intermediate-risk locally advanced rectal cancer found that dynamic ctDN…
A blood test tracking tumor DNA during chemo can predict which rectal cancer patients won't respond well to treatment before surgery.
Oral nutritional interventions associated with reduced clinical events in adults with cirrhosis
Can better nutrition help people with advanced liver disease?
A systematic review and meta-analysis of 3,128 adults with cirrhosis found oral nutritional interventions were associated with reduced risks…
Better nutrition linked to fewer hospital visits and lower risk of serious problems for adults with advanced liver disease.
Meta-analysis links higher BMI to increased early-onset colorectal cancer risk
Does weight affect colon cancer risk in younger adults? A new analysis finds a link.
A systematic review and meta-analysis of 11 cohort studies found that overweight/obesity (BMI ≥25 kg/m²) was associated with higher early-on…
Being overweight or obese is linked to a 59% higher risk of colon cancer before age 50, with men and those with obesity facing the greatest …
Regular antithrombotic use associated with increased nonbiliary pancreatitis risk in UK Biobank cohort
Large UK study finds link between blood-thinning drugs and pancreatitis risk
A prospective cohort study of 431,754 UK Biobank participants found regular antithrombotic drug use was associated with a 31% increased risk…
Regular blood-thinning drug use is linked to a 31% higher risk of a specific pancreatitis type, with clopidogrel showing the strongest conne…