Laparoscopic hemihepatectomy shows higher costs but better QALYs than open approach in European trial
Laparoscopic surgery costs more upfront but may offer better value for some liver patients
A phase 3 randomized controlled trial of 332 patients undergoing hemihepatectomy at 16 European centers found laparoscopic surgery had highe…
Laparoscopic liver surgery costs more upfront but delivers better long-term value and quality of life for patients.
Network meta-analysis finds pegozafermin, OCA, and resmetirom outperform placebo for MASLD fibrosis improvement
New Liver Treatments Show Real Promise in Reversing Scarring
A systematic review and network meta-analysis of 10,119 adult patients with MASLD found pegozafermin, obeticholic acid (OCA), and resmetirom…
For the first time, doctors have clear evidence that new medications can help reverse the dangerous liver scarring caused by common fatty li…
Cognitive-behavioral sleep intervention with nutritional support improves sleep, survival in rectal cancer surgery patients
A Simple Pre-Surgery Habit Change Boosts Cancer Survival Rates
A single-center RCT of 186 stage I-III rectal cancer patients found that adding cognitive-behavioral sleep intervention with nutritional sup…
Teaching patients how to sleep and eat better before a major cancer surgery doesn’t just help them recover—it may help them live longer.
Diet-induced liver fat reduction associated with fasting metabolite changes but not postprandial responses
Your Liver Fat May Be Changing Your Blood After Meals
An integrated RCT and cohort study in 1986 individuals and 80 intervention participants examined liver fat associations with metabolite prof…
What happens in your blood after a meal could be a clearer sign of liver health than a standard fasting test.
SBCE as initial investigation reduces DBE referrals in suspected small bowel Crohn's disease cohort
Skip the invasive scope with this new rule
This retrospective cohort analysis of 98 patients referred for suspected small bowel Crohn's disease compared SBCE as initial investigation …
A simple pill-sized camera can now rule in or out Crohn's disease for 70% of patients, saving them from a more invasive follow-up test.
Endoscopic findings predict advanced gastric signet ring cell carcinoma in CDH1 carriers.
A Safer Path for Families with Hereditary Stomach Cancer?
This retrospective observational study examined 390 CDH1 pathogenic variant carriers from 235 families across twelve academic centers. The a…
For families with a high genetic risk for stomach cancer, new research shows advanced tumors often have visible warning signs during standar…
Efruxifermin shows superior fibrosis regression in compensated MASH cirrhosis compared to placebo in a network meta-analysis.
New drug ranking shows one treatment stands out for advanced fatty liver scarring
This network meta-analysis evaluated histological efficacy in patients with biopsy-proven compensated metabolic dysfunction-associated steat…
Efruxifermin is the only drug proven to shrink advanced liver scarring without worsening the disease, ranking first among new treatments for…
Carbapenem-resistant hypervirulent Klebsiella pneumoniae infection is associated with significantly higher mortality compared to carbapenem-susceptible strains in 4240 patients.
Resistant superbugs kill more than 12 times as often as susceptible strains in severe infections
This systematic review and meta-analysis evaluated clinical outcomes in 4240 patients with hypervirulent Klebsiella pneumoniae (HvKp) infect…
When bacteria resists last-resort antibiotics, patients with severe infections face a 57% death risk instead of 21%.
Hyperferritinemia is associated with higher liver-related event incidence in patients with metabolic dysfunction-associated steatotic liver disease.
Is high iron protein in your blood a warning sign for worse liver disease outcomes?
This meta-analysis pooled data from 16 observational studies involving 49,754 patients with metabolic dysfunction-associated steatotic liver…
High iron protein levels in blood nearly double the risk of serious liver events for patients with fatty liver disease, flagging a group nee…
Network meta-analysis ranks exercise types for colorectal cancer survivors post-resection based on specific outcomes.
Exercise types ranked for colorectal cancer survivors after surgery
This network meta-analysis evaluated aerobic training (AT), resistance training (RT), combined training (CT), and high-intensity interval tr…
This network meta-analysis compared aerobic, resistance, combined, and high-intensity interval training for colorectal cancer survivors afte…
Meta-analysis finds fatty pancreas disease in over half of adults with MASLD
Do you have fatty liver? A new look suggests your pancreas might be fatty too.
A systematic review and meta-analysis of 11 observational studies including 21,438 adults with metabolic dysfunction-associated steatotic li…
If you have fatty liver disease, your pancreas is likely fatty too, with rates reaching over 75% in non-Asian groups and 35% in Asian popula…
Antenatal pelvic floor exercise reduces perineal laceration risk in primiparous women during vaginal delivery.
Want to Avoid Tearing During Childbirth? Science Points to One Clear Winner
This Bayesian network meta-analysis of randomized controlled trials evaluated physical interventions in 10,745 primiparous women across 15 h…
Simple pelvic floor exercises during pregnancy cut the risk of painful childbirth tears by half, outperforming massage and education alone.