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Infectious Disease

1161 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Antimicrobial resistance drivers in human and agricultural sectors contribute to 4.95 million annual deaths
Infectious Disease Sys. Review
Antimicrobial resistance drivers in human and agricultural sectors contribute to 4.95 million annual deaths Antimicrobial resistance linked to 4.95 million deaths in 2019
This narrative review examines the global burden of antimicrobial resistance (AMR) across human, livestock, and environmental settings. It i…
A global review finds antimicrobial resistance tied to nearly 5 million deaths in 2019, with overuse of antibiotics a key driver.
Intravesical aminoglycoside instillations reduce recurrent urinary tract infection risk with an IRR of 0.23
Infectious Disease Meta-analysis
Intravesical aminoglycoside instillations reduce recurrent urinary tract infection risk with an IRR of 0.23 New findings show ways to reduce recurring urinary tract infections
This systematic review and meta-analysis of 25 studies evaluates intravesical instillations for preventing recurrent urinary tract infection…
Doctors are looking at new ways to stop repeat urinary tract infections using local treatments like aminoglycosides or hyaluronic acid.
Comparing antimicrobial resistance to COVID-19 does not reduce antibiotic seeking intentions in US adults
Infectious Disease RCT
Comparing antimicrobial resistance to COVID-19 does not reduce antibiotic seeking intentions in US adults Comparing Antibiotic Resistance to COVID-19 May Not Change Patient Behavior
This randomized online survey of 972 US adults evaluated three messaging types regarding antimicrobial resistance (AMR) and the COVID-19 pan…
Comparing the threat of antibiotic resistance to the COVID-19 pandemic did not change how many people intended to seek unnecessary antibioti…
Ensitrelvir plus standard of care does not improve clinical recovery in hospitalized COVID-19 patients
Infectious Disease RCT
Ensitrelvir plus standard of care does not improve clinical recovery in hospitalized COVID-19 patients Trial shows ensitrelvir does not improve recovery for COVID-19
This Phase 3 randomized controlled trial of 589 adults hospitalized with COVID-19 found that ensitrelvir added to standard of care did not s…
A large trial found that adding ensitrelvir to standard care did not speed up clinical recovery for adults hospitalized with COVID-19.
4CMenB vaccine did not reduce infection rates compared to placebo in MSM population
Infectious Disease RCT
4CMenB vaccine did not reduce infection rates compared to placebo in MSM population Trial shows 4CMenB vaccine does not prevent gonorrhea or syphilis
This randomized controlled trial evaluated 4CMenB in 587 men who have sex with men (MSM) recently diagnosed with gonorrhea or infectious syp…
A large trial found that a new vaccine did not reduce the rates of gonorrhea or syphilis infections in men at high risk for these conditions…
Voriconazole and surgical management successfully treated Aspergillus flavus infection in a patient with spondylolisthesis
Infectious Disease Sys. Review
Voriconazole and surgical management successfully treated Aspergillus flavus infection in a patient with spondylolisthesis Combined surgery and antifungal drugs clear deep spinal infection
This case report and literature review describes the successful treatment of an Aspergillus flavus infection using staged voriconazole and s…
A 74-year-old man with a severe spine infection found relief through a combination of specialized surgery and targeted antifungal medication…
FDA Approves Augmentin XR (amoxicillin/clavulanate) for Community-Acquired Pneumonia and Acute Bacterial Sinusitis
Infectious Disease FDA Approval
FDA Approves Augmentin XR (amoxicillin/clavulanate) for Community-Acquired Pneumonia and Acute Bacterial Sinusitis FDA approves new antibiotic Augmentin XR for pneumonia and sinusitis.
The FDA approved Augmentin XR (amoxicillin/clavulanate potassium extended-release tablets) for community-acquired pneumonia and acute bacter…
The FDA approved Augmentin XR, an extended-release antibiotic, for adults and some children with community-acquired pneumonia or acute bacte…
FDA Approves Augmentin (amoxicillin/clavulanate) for Bacterial Infections
Infectious Disease FDA Approval
FDA Approves Augmentin (amoxicillin/clavulanate) for Bacterial Infections FDA approves Augmentin for bacterial infections including sinusitis and UTIs.
The FDA approved Augmentin (amoxicillin and clavulanate potassium) for lower respiratory tract infections, acute bacterial otitis media, sin…
The FDA approved Augmentin, a combination antibiotic, for several bacterial infections like sinusitis, ear infections, and urinary tract inf…
FDA Approves Augmentin (amoxicillin/clavulanate) for Bacterial Infections
Infectious Disease FDA Approval
FDA Approves Augmentin (amoxicillin/clavulanate) for Bacterial Infections FDA approves new antibiotic Augmentin for bacterial infections
FDA approved Augmentin (amoxicillin/clavulanate) for lower respiratory tract infections, acute otitis media, sinusitis, skin infections, and…
The FDA approved Augmentin, a combination of amoxicillin and clavulanate, to treat bacterial infections like sinusitis, ear infections, and …
Nocardia keratitis virulence factors and host immune pathways mapped in systematic review
Infectious Disease Sys. Review
Nocardia keratitis virulence factors and host immune pathways mapped in systematic review New research reveals how Nocardia bacteria invade and survive in tissue
This systematic review synthesizes evidence on Nocardia keratitis pathogenesis, identifying virulence factors involved in adhesion, coloniza…
Scientists are uncovering the specific ways Nocardia bacteria stick to, invade, and survive inside human tissue to cause eye infections.
Genome-predicted PBP profiling shows high agreement with phenotypic testing for pneumococcal beta-lactam susceptibility
Infectious Disease Sys. Review
Genome-predicted PBP profiling shows high agreement with phenotypic testing for pneumococcal beta-lactam susceptibility Genome test predicts pneumococcal antibiotic resistance accurately
This mini review evaluates the use of genome-predicted beta-lactam susceptibility based on PBP1a, PBP2b, and PBP2x to predict drug-specific …
A new review finds that genome-based testing can accurately predict whether pneumococcal bacteria will resist beta-lactam antibiotics.
Chinese pediatric surgeons know prophylaxis guidelines but often fail to stop antibiotics at 24 hours
Infectious Disease Guideline
Chinese pediatric surgeons know prophylaxis guidelines but often fail to stop antibiotics at 24 hours Surgeons show high knowledge but inconsistent habits with antibiotics
A cross-sectional survey of 143 pediatric surgeons in Jiangsu, China, found high knowledge of perioperative antibiotic prophylaxis but gaps …
While pediatric surgeons know the rules for using antibiotics before surgery, many still struggle to follow specific timing guidelines for c…