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Infectious Disease

1161 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
HIV-related factors including antiretroviral therapy and low CD4+ counts associate with higher cardiovascular risk
Infectious Disease Meta-analysis
HIV-related factors including antiretroviral therapy and low CD4+ counts associate with higher cardiovascular risk HIV infection and certain factors increase heart health risks
This meta-analysis of observational studies involving 4,175,459 individuals identifies significant associations between HIV-related factors …
A massive review of over 4 million people shows how HIV and specific health markers impact the risk of heart attacks and strokes.
SP+AQ cuts malaria incidence 54.6% versus SP alone in African children
Infectious Disease Sys. Review
SP+AQ cuts malaria incidence 54.6% versus SP alone in African children Adding amodiaquine to sulfadoxine-pyrimethamine reduces malaria in children
This meta-analysis of 32 sites across 13 African countries found that sulfadoxine-pyrimethamine plus amodiaquine (SP+AQ) reduced malaria inc…
Combining two medicines significantly lowers malaria rates in children across Africa compared to using only one drug.
Dolutegravir and lamivudine achieved 78% HIV-1 RNA suppression in patients with isolated reactive anti-HBc
Infectious Disease RCT
Dolutegravir and lamivudine achieved 78% HIV-1 RNA suppression in patients with isolated reactive anti-HBc Trial shows dolutegravir and lamivudine are safe for patients with HIV
This pooled analysis of Phase 3/3b trials evaluated dolutegravir/lamivudine (DTG/3TC) in adults with HIV-1 and isolated reactive hepatitis B…
A review of multiple trials shows that a common two-drug regimen effectively manages HIV while remaining safe for those with hepatitis B ant…
Impact of Rapid Multiplex Point of Care Testing on Antibiotic Prescribing
Infectious Disease RCT
Impact of Rapid Multiplex Point of Care Testing on Antibiotic Prescribing Rapid testing shows mixed results for reducing common antibiotic use
A randomized trial evaluates if rapid multiplex testing reduces same-day antibiotic prescriptions for respiratory infections in children and…
A new rapid test to identify respiratory viruses did not reduce overall antibiotic prescriptions, but showed potential for specific patient …
Multidrug-resistant tuberculosis prevalence is 5.2% among patients with bacteriologically confirmed cases in Cameroon
Infectious Disease Meta-analysis
Multidrug-resistant tuberculosis prevalence is 5.2% among patients with bacteriologically confirmed cases in Cameroon Identifying key risks for drug resistant tuberculosis infections in Cameroon
This meta-analysis of 28 studies involving 9,931 patients identifies a 5.2% pooled prevalence of multidrug-resistant tuberculosis (MDR-TB) i…
New data shows that past infections and lifestyle factors like alcohol use can increase the risk of developing hard-to-treat tuberculosis.
Tablet-guided training improves HIV index case testing fidelity by 30.5 percentage points
Infectious Disease RCT
Tablet-guided training improves HIV index case testing fidelity by 30.5 percentage points Tablet training boosts HIV counseling skills in Malawi
This cluster randomized controlled trial of 306 lay health care workers in Malawi found that tablet-guided training improved knowledge, atti…
Adding tablet-guided training to standard HIV counseling education improved knowledge and skills among health workers in Malawi.
Bidirectional automated texting engages 60.3% of people living with HIV for cardiovascular health
Infectious Disease RCT
Bidirectional automated texting engages 60.3% of people living with HIV for cardiovascular health Automated texting helps people living with HIV manage heart health
This observational cohort analysis of 471 people living with HIV evaluated a bidirectional automated texting (BAT) program for cardiovascula…
A new look at automated texting shows it is a practical way to help people living with HIV manage heart health and stay engaged in care.
Fidaxomicin and vancomycin pulse and taper regimens show potential for reducing Clostridioides difficile recurrence
Infectious Disease Meta-analysis
Fidaxomicin and vancomycin pulse and taper regimens show potential for reducing Clostridioides difficile recurrence Fidaxomicin and Vancomycin Pulse Regimens May Reduce Infection Recurrence
Researchers evaluated various treatment regimens, including fidaxomicin and vancomycin pulse and taper strategies, for managing Clostridioid…
New analysis suggests that specific dosing schedules for fidaxomicin and vancomycin may be more effective at preventing recurring C. diffici…
Targeted interventions increase condom use and HIV knowledge among long-distance truck drivers
Infectious Disease Meta-analysis
Targeted interventions increase condom use and HIV knowledge among long-distance truck drivers Targeted programs improve HIV prevention for long distance truck drivers
This systematic review and meta-analysis of 24 studies evaluated targeted interventions for HIV prevention in long-distance truck drivers. R…
Specific outreach programs help long distance truck drivers increase condom use and knowledge to better prevent HIV infection.
Dual-ART and triple-ART both reduce plasma biomarkers of immune activation and neuronal injury
Infectious Disease RCT
Dual-ART and triple-ART both reduce plasma biomarkers of immune activation and neuronal injury Dual-ART Therapy Shows Lower Brain Inflammation for People with HIV
This randomized controlled trial of 238 adults initiating ART found that both dual-ART and triple-ART regimens significantly reduced markers…
A new trial shows that a specific dual-drug treatment may lower markers of brain inflammation and injury in adults living with HIV.
Magnesium phosphate cements demonstrate superior biological interactions and faster resorption than calcium phosphate cements
Infectious Disease Sys. Review
Magnesium phosphate cements demonstrate superior biological interactions and faster resorption than calcium phosphate cements Magnesium Phosphate Cements Show Better Biological Interaction Than Calcium Options
This mini review examines the properties of magnesium phosphate cements (MPCs) compared to calcium phosphate cements (CPCs). The authors con…
New research suggests magnesium phosphate cements may offer better biological interactions and faster resorption than traditional calcium ph…
Chlorhexidine reduces alveolar osteitis risk by 42.9% after third molar surgery
Infectious Disease Meta-analysis
Chlorhexidine reduces alveolar osteitis risk by 42.9% after third molar surgery Chlorhexidine Reduces Risk of Painful Infection After Wisdom Tooth Surgery
This meta-analysis found that chlorhexidine supplementation after third molar surgery significantly reduces the incidence of alveolar osteit…
A review of clinical data shows that using chlorhexidine after wisdom tooth surgery can significantly lower the risk of painful infections.