Moxifloxacin achieves 87.0% microbiological cure in Mycoplasma genitalium compared to 61.2% for azithromycin
Trial shows moxifloxacin more effective than azithromycin for MG
This randomized trial of 358 adults with Mycoplasma genitalium infection found moxifloxacin 400 mg daily for 10 days superior to azithromyci…
A new trial shows moxifloxacin has a higher success rate than azithromycin for treating Mycoplasma genitalium infections in adults.
Sensititre MYCOTB shows high diagnostic accuracy for rifampicin and isoniazid in tuberculosis isolates
New test shows high accuracy for detecting drug resistant tuberculosis
This meta-analysis of 1,728 isolates evaluates the diagnostic performance of Sensititre MYCOTB against reference drug susceptibility testing…
A new testing method shows high accuracy in identifying which drugs can successfully treat drug-resistant tuberculosis infections.
Typhoidal Salmonella pathogenesis involves a unified network of virulence determinants and metabolic proteins
New Research Identifies Targets for Typhoid Fever Treatments
This systematic review synthesizes the molecular and structural architecture of typhoidal Salmonella pathogenesis. It identifies key protein…
Scientists have mapped the complex structures of the bacteria causing typhoid fever to help identify new targets for vaccines and better tre…
Pegylated erythropoietin provides improved Hb stability and reduced dosing frequency in CKD-related anemia
Expert Consensus Shows Pegylated Erythropoietin Benefits Chronic Kidney Disease Patients
This expert consensus evaluates the use of pegylated erythropoietin for CKD-related anemia in India. The consensus indicates that pegylated …
A new expert consensus suggests that pegylated erythropoietin can improve hemoglobin stability and reduce dosing frequency for patients with…
Structured exercise improves quality of life and VO2 max in older adults with HIV
Structured Exercise Programs Improve Quality of Life for Older Adults Living with HIV
This meta-analysis of 372 older adults living with HIV found that structured exercise significantly improved quality of life and VO2 max, bu…
Regular exercise can significantly improve daily life and fitness for older adults living with HIV, though it may not change sleep patterns.
Corticosteroids added to antiviral therapy do not improve outcomes in herpes simplex virus encephalitis
Adding corticosteroids to antiviral therapy for herpes encephalitis shows no benefit
This meta-analysis of 209 patients with herpes simplex virus encephalitis (HSVE) found no significant difference in mortality or neurologica…
Adding steroids to antiviral drugs does not improve survival or outcomes for patients with herpes simplex virus encephalitis.
Expanded TB Screening in HIV Inpatients Shows No Benefit
Expanded Screening Does Not Speed Tuberculosis Treatment for HIV Patients
In HIV-positive hospital inpatients, expanded TB screening with Xpert Ultra and LF-LAM did not improve treatment initiation or 8-week mortal…
A large trial in Tanzania and Mozambique found that expanded screening did not speed up tuberculosis treatment or reduce deaths for patients…
MRSA nares PCR does not cut vancomycin duration in ICU CAP
MRSA Testing Does Not Reduce Vancomycin Use in Pneumonia Patients
In a single-center randomized trial of 277 adult ICU patients with suspected community-acquired pneumonia, MRSA nares PCR testing did not si…
A trial of 277 ICU patients found that MRSA nasal swab testing did not reduce the amount of vancomycin used for pneumonia.
Baricitinib plus remdesivir recovery benefit similar across BMI in COVID-19
Adding baricitinib to remdesivir for COVID-19 shows consistent results
This secondary analysis of a randomized trial in 942 hospitalized adults with COVID-19 found that baricitinib plus remdesivir improved time …
New data shows that adding the drug baricitinib to remdesivir helps hospitalized COVID-19 patients recover regardless of their body weight.
Efavirenz 400 mg Shows Noninferiority to 600 mg in Treatment-Naïve Chinese Patients
Trial shows lower dose of efavirenz works for HIV treatment
Efavirenz 400 mg achieves comparable virological suppression to 600 mg while demonstrating a more favorable safety profile in HIV-1 patients…
A lower dose of the HIV medication efavirenz may offer similar effectiveness with fewer serious side effects for some patients.
FDA Approves Cleocin Hydrochloride (clindamycin) for Serious Infections
FDA approves Cleocin Hydrochloride capsules to treat serious bacterial infections.
The FDA approved Cleocin Hydrochloride (clindamycin) for the treatment of serious infections caused by susceptible anaerobic bacteria, strep…
The FDA has approved Cleocin Hydrochloride (clindamycin) capsules for serious infections caused by certain bacteria. It is for patients alle…
Home visits and HIV self-testing increase CHTC uptake to 56.2% and 50.0% in pregnant couples
Home visits and self-test kits boost couples HIV testing
This randomized controlled trial of 800 pregnant couples in Kenya found that home visits and HIV self-test kits significantly increased CHTC…
Pregnant couples in Kenya were far more likely to get tested together when offered home visits or self-test kits, a new trial finds.