Sotorasib resistance linked to transformation to pulmonary giant cell carcinoma in KRAS G12C lung adenocarcinoma
Lung cancer can change form after targeted drug treatment
A case report with literature review describes a 71-year-old man with KRAS G12C-mutant lung adenocarcinoma whose tumor transformed to pulmon…
A man's lung cancer transformed into a more aggressive type after taking the targeted drug sotorasib, highlighting the need for re-biopsy wh…
Antimicrobial additives in resin-based endodontic sealers enhance antibacterial activity against Enterococcus faecalis
Additives help fight bacteria in root canal infection treatments
This scoping review of 33 studies synthesized the impact of antimicrobial additives like nanoparticles and chlorhexidine on resin-based endo…
Adding antimicrobial agents to dental sealers can better fight deep infections while keeping the material safe and stable.
Multimodal laboratory diagnostics improve detection of biofilm-encased pathogens and polymicrobial infections in bone and joint infections
New Laboratory Tools Improve Diagnosis of Bone and Joint Infections
This narrative review synthesizes current evidence regarding laboratory diagnostics for bone and joint infections, including serum markers, …
Advanced molecular tests and tissue processing are improving how doctors identify complex bone and joint infections that traditional culture…
Image-guided RFA and MWA show comparable efficacy and safety for small to medium hepatocellular carcinoma
Radiofrequency and microwave ablation show similar results for liver cancer
This meta-analysis of 19 studies compared image-guided radiofrequency ablation (RFA) and microwave ablation (MWA) for small to medium hepato…
Two common types of heat-based treatments for small to medium liver cancer show nearly identical success rates and safety profiles.
NLRP3 inhibition and IL-1 receptor blockade attenuate musculoskeletal pathology in alphavirus infections
Targeting specific proteins may reduce joint damage from viral infections
This mini review synthesizes preclinical data regarding NLRP3 inflammasome activation during Chikungunya, Ross River, and Mayaro virus infec…
New research suggests that blocking certain inflammatory pathways could protect bones and joints from damage caused by Chikungunya, Mayaro, …
Syphilis prevalence is 5.20-fold higher in low-income countries among forcibly displaced populations
High Rates of Syphilis Found Among Displaced Populations
This meta-analysis of 1.1 million test results across 82 reports evaluates the prevalence of syphilis, gonorrhea, chlamydia, and trichomonia…
A large-scale review reveals high rates of syphilis and other infections among refugees, highlighting the need for better screening in these…
TCM-based extracts reduce pain in oral lichen planus by 0.86 points on VAS
TCM Biological Extracts May Reduce Pain in Oral Lichen Planus
A meta-analysis of 22 articles found that traditional Chinese Medicine-based biological extracts significantly reduce visual analog scale sc…
New research suggests that traditional Chinese medicine based biological extracts may help reduce pain for people living with oral lichen pl…
NSP antibody detection aids DIVA interpretation in foot-and-mouth disease but has key limits
New ways to tell if livestock are vaccinated against disease
This mini review examines non-structural protein (NSP) antibody detection for DIVA serology in foot-and-mouth disease. It finds that NSP ser…
Identifying whether an animal was vaccinated or infected by a virus is tricky, but new protein markers may help clarify the history of infec…
Brain-Lung-Immune-Microbiome Axis replaces biomechanical models in understanding ventilator-associated pneumonia after traumatic brain injury
New Framework Explains Lung Infections After Brain Injuries
This narrative review explores the transition from a traditional biomechanical model of ventilator-associated pneumonia to a multidimensiona…
A new model suggests that brain injuries create a complex immune and microbiome response that leads to lung infections in intensive care pat…
FDA Approves Zithromax (azithromycin) for Mild to Moderate Bacterial Infections
FDA approves Zithromax to treat bacterial infections in adults and children.
The FDA approved Zithromax (azithromycin) for mild to moderate infections caused by susceptible bacteria, including acute bacterial exacerba…
The FDA approved Zithromax (azithromycin) for mild to moderate bacterial infections like bronchitis, sinusitis, pneumonia, and ear infection…
FDA Approves Zithromax (azithromycin) for Mild to Moderate Bacterial Infections
FDA approves new antibiotic Zithromax for bacterial infections
The FDA approved Zithromax (azithromycin) for mild to moderate infections caused by susceptible bacteria, including acute bacterial exacerba…
The FDA approved Zithromax (azithromycin) to treat mild to moderate bacterial infections like bronchitis, sinusitis, pneumonia, and skin inf…
FDA Approves Zithromax (azithromycin) for Multiple Bacterial Infections
FDA approves Zithromax to treat bacterial infections in adults and children.
The FDA approved Zithromax (azithromycin) for mild to moderate infections including acute bacterial exacerbations of chronic bronchitis, sin…
The FDA approved Zithromax (azithromycin) for mild to moderate bacterial infections like bronchitis, sinusitis, pneumonia, and skin infectio…