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Nephrology

111 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Meta-analysis shows systemic heparinization reduces early patency loss in adult AVF or graft placement
Nephrology Meta-analysis
Meta-analysis shows systemic heparinization reduces early patency loss in adult AVF or graft placement Systemic heparin lowers early clot risk but raises bleeding danger for arm access patients
This meta-analysis evaluated systemic heparinization versus standard care in adults undergoing arm arteriovenous fistula or graft placement.
A large analysis shows systemic heparin cuts early clot risk for arm access but increases bleeding complications, requiring careful balance.
Systematic review and meta-analysis of health coaching interventions in chronic kidney disease patients
Nephrology Meta-analysis
Systematic review and meta-analysis of health coaching interventions in chronic kidney disease patients Health coaching helps patients with kidney disease lose weight and lower blood pressure
This systematic review and meta-analysis evaluated health coaching interventions in patients with chronic kidney disease.
A review of health coaching shows patients with kidney disease lost weight and lowered blood pressure, though benefits were small and not al…
Amiloride and hydrochlorothiazide affect metabolites and ammonium excretion in CKD patients
Nephrology RCT
Amiloride and hydrochlorothiazide affect metabolites and ammonium excretion in CKD patients Distal diuretics change kidney chemistry in people with chronic kidney disease
This randomized controlled trial in 26 individuals with chronic kidney disease found that distal diuretics decreased plasma glutamine and tr…
A small trial found that taking amiloride and hydrochlorothiazide lowered glutamine and changed how the body handles waste in people with ch…
Kidney-directed SBRT shows modest renal function decline in inoperable patients
Nephrology Phase II
Kidney-directed SBRT shows modest renal function decline in inoperable patients Small study shows kidney function drops after radiation for hard-to-treat tumors
This prospective phase 2 single-arm trial evaluated kidney-directed SBRT in 30 patients with primary or metastatic renal tumors who were med…
Radiation to treat kidney tumors may lower kidney function over two years, even when surgery is not an option.
Pre-admission statin use linked to better 30-day outcomes after aneurysmal SAH
Nephrology RCT
Pre-admission statin use linked to better 30-day outcomes after aneurysmal SAH Pre-admission statin use linked to better 30-day outcomes in brain bleed patients
This observational study of 1,431 patients with aneurysmal subarachnoid hemorrhage found that pre-admission statin use was associated with a…
Using statins before a brain bleed may improve early recovery chances, but benefits did not last to 90 days in this real-world study.
Omega-3 fatty acids fail to reduce inflammation in hemodialysis patients
Nephrology RCT
Omega-3 fatty acids fail to reduce inflammation in hemodialysis patients Short-term omega-3s did not lower inflammation in dialysis patients
This randomized controlled trial tested omega-3 fatty acids (3 g/day) for 2 months in patients with chronic kidney disease undergoing hemodi…
A trial found that taking omega-3 capsules for two months did not reduce inflammatory markers in patients with chronic kidney disease on hem…
Meta-analysis shows active surveillance and ablative therapy for small renal masses have comparable cancer-specific survival
Nephrology Meta-analysis
Meta-analysis shows active surveillance and ablative therapy for small renal masses have comparable cancer-specific survival Active surveillance vs ablation for small kidney tumors: what works?
This systematic review and meta-analysis evaluates active surveillance (AS) versus ablative therapy (AT) for patients with small renal masse…
For small kidney tumors, ablation may boost survival, but cancer-specific death risk is similarly low with either approach.
Nephrometry Scores Show Limited Discrimination for Adverse Outcomes After RAPN in Larger Renal Tumors
Nephrology Cohort
Nephrometry Scores Show Limited Discrimination for Adverse Outcomes After RAPN in Larger Renal Tumors Tumor complexity scores predict longer surgery time but not major complications in kidney cancer removal
This retrospective cohort study of 109 patients with pT1b–pT2a renal tumors found that PADUA and RENAL nephrometry scores had limited discri…
Scores measuring kidney tumor complexity predicted longer surgery time but failed to predict major complications in 109 patients.
Review of environmental exposures in agricultural communities with chronic kidney disease of unknown cause
Nephrology
Review of environmental exposures in agricultural communities with chronic kidney disease of unknown cause New research hunts the hidden causes of kidney disease in farming communities
This publication is a review examining potential environmental exposures in agricultural communities in Central America and South Asia. The …
A new study hunts for the hidden causes of kidney disease in farming communities across Central America and South Asia.
Systematic review and meta-analysis of MRAs in dialysis patients shows reduced nonfatal CVD events but elevated hyperkalemia and gynecomastia risks
Nephrology Meta-analysis
Systematic review and meta-analysis of MRAs in dialysis patients shows reduced nonfatal CVD events but elevated hyperkalemia and gynecomastia risks New analysis shows dialysis drugs cut heart attacks but raise dangerous potassium risks
This systematic review and meta-analysis evaluated mineralocorticoid receptor antagonists (MRAs) in adults on maintenance dialysis.
A large review of dialysis patients found that specific heart drugs reduced nonfatal heart events but increased risks of severe potassium bu…
Systematic Review and Meta-Analysis Links α-Klotho to Frailty and Bone Health in Aging
Nephrology Meta-analysis
Systematic Review and Meta-Analysis Links α-Klotho to Frailty and Bone Health in Aging Higher Alpha-Klotho Levels Mean Less Frailty And Better Bones
This systematic review and meta-analysis of 109 studies found that higher circulating α-Klotho levels were associated with lower odds of fra…
New research shows that higher Alpha-Klotho levels protect against frailty and bone loss, offering hope for better aging outcomes.
Pre-treatment body composition and acute kidney disease risk in head and neck cancer patients treated with cisplatin
Nephrology Cohort
Pre-treatment body composition and acute kidney disease risk in head and neck cancer patients treated with cisplatin Body composition may link to kidney issues in cancer patients
This prospective, monocentric, observational study of 110 patients with locally advanced head and neck cancer found that acute kidney diseas…
Low muscle mass and low lymphocyte counts may be linked to kidney disease risk during head and neck cancer treatment.