FDA Approves Sodium Bicarbonate Injection for Metabolic Acidosis and Urinary Alkalization
FDA Approves New Ready-to-Use Sodium Bicarbonate Injection for Acidosis and Poisoning
The FDA has approved sodium bicarbonate injection (NDA218524) for raising plasma pH in adults and pediatric patients with clinically signifi…
The FDA approved a new form of sodium bicarbonate injection. It treats serious acid buildup in the blood and helps clear certain poisons thr…
HIF-prolyl hydroxylase inhibitors cause modest VEGF increases and reproducible peripheral edema in chronic kidney disease
New data shows how kidney disease drugs affect blood levels
This meta-analysis of 34 randomized controlled trials evaluated HIF-prolyl hydroxylase inhibitors in patients with chronic kidney disease. T…
A review of 34 trials shows that a specific type of kidney medication increases a protein called VEGF, but also carries a risk of swelling.
Roxadustat-based regimens result in higher mean hemoglobin levels than ESA-based regimens in peritoneal dialysis
Roxadustat shows higher hemoglobin levels for patients on peritoneal dialysis
This meta-analysis of 1636 adults with renal anemia indicates that roxadustat-based regimens lead to a mean difference of 7.30 g/L in post-t…
A new analysis shows roxadustat may raise hemoglobin levels and lower adverse event rates for adults on peritoneal dialysis.
Iron chelation reduces serum ferritin and iron while increasing hemoglobin in chronic kidney disease
Iron Chelators May Reduce Iron Levels in Chronic Kidney Disease
This meta-analysis of 206 patients with chronic kidney disease found that iron chelation significantly reduces serum ferritin (WMD: -1.48 μg…
Iron chelation therapy may help lower iron stores and improve hemoglobin levels for adults living with chronic kidney disease.
SGLT2 inhibitors attenuate urinary EGF decline and correlate with improved outcomes in chronic kidney disease
New Kidney Health Marker Helps Predict Success of SGLT2 Inhibitor Treatment
Researchers evaluated the relationship between urinary EGF levels and kidney outcomes in patients with chronic kidney disease treated with S…
A new urine test helps doctors track kidney health and see how well certain medications protect the kidneys in patients with diabetes.
Coagulopathy and hemodialysis significantly increase odds of post-ERCP bleeding in patients with cirrhosis
Risk factors for bleeding during and after ERCP procedures identified
This meta-analysis of 149,870 patients identified several risk factors for post-ERCP bleeding. Significant associations were found for coagu…
Identifying specific risk factors like cirrhosis and blood-thinning medications helps doctors better manage bleeding risks during ERCP proce…
Selective aldosterone synthase inhibitors reduce systolic blood pressure by 7.9 mmHg in patients with CKD
Aldosterone Synthase Inhibitors May Lower Blood Pressure in CKD Patients
This meta-analysis of 1148 patients with CKD and uncontrolled hypertension found that selective aldosterone synthase inhibitors (ASIs) reduc…
New research suggests that aldosterone synthase inhibitors could help manage high blood pressure and kidney damage in patients with chronic …
Hypoglycemia prediction models show a pooled AUC of 0.846 for patients with diabetic kidney disease
Prediction models may help identify low blood sugar in dialysis patients
This meta-analysis evaluates the performance of hypoglycemia risk prediction models in patients with diabetic kidney disease undergoing haem…
New data shows that specific prediction models can help identify the risk of low blood sugar for patients with diabetic kidney disease on di…
FDA Approves Dextrose 5% and Sodium Chloride 0.11% in Plastic Container for Hydration
FDA Approves New IV Fluid for Hydration and Electrolytes
The FDA has approved dextrose 5% and sodium chloride 0.11% in a plastic container, an intravenous solution indicated in adults and pediatric…
The FDA has approved a new intravenous solution that combines dextrose and a small amount of sodium chloride. It is used in adults and child…
DNS-based interventions may reduce low back pain, but heterogeneity is substantial
New Exercise Approach May Ease Low Back Pain, Review Finds
This meta-analysis of 289 individuals with nonspecific low back pain found that Dynamic Neuromuscular Stabilization (DNS)-based intervention…
A review of 289 people suggests a movement-based approach may help low back pain, but the evidence is far from settled.
Pulmonary hypertension prevalence 37% in maintenance hemodialysis patients, meta-analysis finds
High Rates of Pulmonary Hypertension Found in Dialysis Patients
This meta-analysis of 6,633 maintenance hemodialysis patients estimates a 37% prevalence of pulmonary hypertension (95% CI 0.32-0.42). Multi…
Nearly 40% of patients on maintenance hemodialysis have pulmonary hypertension, highlighting the need for early detection and careful heart …
Virtual reality interventions improve gait speed and reduce pain and depressive symptoms in hemodialysis patients
Virtual reality helps patients on long-term hemodialysis manage pain and anxiety
This meta-analysis of 19 studies involving 1228 adults on long-term hemodialysis found that virtual reality (VR) interventions significantly…
Virtual reality may help people on long-term hemodialysis manage pain, improve walking speed, and reduce feelings of anxiety and depression.