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Nephrology

75 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Metabolic syndrome associated with higher cardio-renal risk in kidney transplant recipients
Nephrology Meta-analysis
Metabolic syndrome associated with higher cardio-renal risk in kidney transplant recipients Metabolic syndrome linked to higher risks for heart problems and kidney graft issues after transplant
A meta-analysis of 8,986 kidney transplant recipients found metabolic syndrome was associated with higher risks of major adverse cardiovascu…
Kidney transplant patients with metabolic syndrome face double the risk of major heart events and higher chances of graft failure or death.
Standardized sonographic parameters POV and PVD show association with chronic injury in kidney transplant dysfunction
Nephrology Cohort
Standardized sonographic parameters POV and PVD show association with chronic injury in kidney transplant dysfunction Can an ultrasound scan spot hidden damage in a transplanted kidney?
A retrospective single-center cohort study of 350 kidney transplant biopsies found that standardized sonographic parameters POV and PVD were…
Two ultrasound measurements linked to kidney scarring could help doctors spot damage in transplants without invasive biopsies.
NGAL biomarker shows promise for AKI detection and peritoneal dialysis-related peritonitis management
Nephrology Sys. Review
NGAL biomarker shows promise for AKI detection and peritoneal dialysis-related peritonitis management Review finds NGAL biomarker shows promise for detecting kidney injury and infection
A narrative review suggests neutrophil gelatinase-associated lipocalin (NGAL) has significant promise for early acute kidney injury detectio…
A new protein marker shows strong promise for early detection of sudden kidney injury and dangerous infections in dialysis patients.
Cystinosis patients show larger neural conflict monitoring differences versus controls in observational study
Nephrology
Cystinosis patients show larger neural conflict monitoring differences versus controls in observational study Study finds differences in brain conflict monitoring in people with cystinosis
An observational study of 36 individuals with cystinosis and 39 age-matched controls found that those with cystinosis presented larger diffe…
People with cystinosis show slower, less accurate brain responses to conflicting information compared to peers, requiring more mental effort…
Narrative review describes inflammatory and lipotoxicity mechanisms in obesity-related chronic kidney disease
Nephrology Sys. Review
Narrative review describes inflammatory and lipotoxicity mechanisms in obesity-related chronic kidney disease Review explores how obesity may harm kidneys through inflammation and fat toxicity
A narrative review examines inflammatory and lipotoxicity mechanisms in patients with obesity-related chronic kidney disease (Ob-CKD). The r…
Obesity harms kidneys through inflammation and fat buildup, causing scarring and damage in people with chronic kidney disease.
FDA Approves Ringer's In Plastic Container (Ringer's solution) for parenteral replacement of extracellular fluid and electrolyte losses.
Nephrology FDA Approval
FDA Approves Ringer's In Plastic Container (Ringer's solution) for parenteral replacement of extracellular fluid and electrolyte losses. The FDA approved a new intravenous fluid called Ringer's In Plastic Container.
The FDA approved Ringer's In Plastic Container for parenteral replacement of extracellular losses of fluid and electrolytes, as required by …
FDA approves new IV fluid to replace lost water and minerals like sodium and potassium for patients needing hydration after surgery or from …
Case report: Liver transplant recipient on dialysis for over 10 months recovered kidney function
Nephrology
Case report: Liver transplant recipient on dialysis for over 10 months recovered kidney function Can a transplanted liver help a failing kidney recover after months on dialysis?
A case report describes a single liver transplant recipient with pre-transplantation acute kidney injury attributed to hepatorenal syndrome …
A patient on dialysis for over 10 months recovered kidney function after a liver transplant, challenging the belief that long-term dialysis …
Atorvastatin evaluated for dyslipidemia in children with steroid-sensitive nephrotic syndrome
Nephrology Phase IV
Atorvastatin evaluated for dyslipidemia in children with steroid-sensitive nephrotic syndrome Can a common cholesterol drug protect children's hearts and kidneys from a hidden danger?
A quasi-experimental study of 100 children aged 8-18 years with steroid-sensitive nephrotic syndrome and dyslipidemia evaluated the effectiv…
A common cholesterol drug called atorvastatin may help children with kidney disease reach safer heart and blood fat levels when diet alone i…
CFZ533 vs Tacrolimus in Kidney Transplant: Phase 2 Study Terminated After Interim Analysis
Nephrology Phase II
CFZ533 vs Tacrolimus in Kidney Transplant: Phase 2 Study Terminated After Interim Analysis Did a new drug for kidney transplant patients work better than standard treatment?
A Phase 2 study comparing the anti-CD40 monoclonal antibody CFZ533 to tacrolimus for preventing organ rejection in kidney transplant recipie…
A planned five-year kidney transplant drug trial ended early after an interim look, leaving the key question about the new treatment's perfo…
TRACK trial to assess low-dose rivaroxaban for MACE in advanced CKD/dialysis patients
Nephrology Phase III
TRACK trial to assess low-dose rivaroxaban for MACE in advanced CKD/dialysis patients Can a low-dose blood thinner protect people with advanced kidney disease from heart attacks and strokes?
The TRACK trial is a global, quadruple-blind, placebo-controlled phase 3 study evaluating low-dose rivaroxaban (2.5 mg) for reducing major a…
A new global study tested whether a low-dose blood thinner safely protects people with advanced kidney disease from heart attacks and stroke…
Acthar studied in FSGS patients undergoing renal transplantation to measure recurrence rate
Nephrology Phase III
Acthar studied in FSGS patients undergoing renal transplantation to measure recurrence rate Can a medication help prevent kidney disease from returning after transplant?
A prospective phase 3 study enrolled 15 renal transplant recipients with primary FSGS to evaluate Acthar. The primary endpoint was the rate …
A new kidney transplant study found that Acthar medication may lower the risk of FSGS returning to the new organ, offering hope to patients …
Phase 2 Study Evaluates Abatacept for Kidney Transplant Recipients
Nephrology Phase II
Phase 2 Study Evaluates Abatacept for Kidney Transplant Recipients Could a new biomarker improve kidney transplant outcomes for patients?
A Phase 2 study is recruiting 800 kidney transplant recipients to assess HLA-DR/DQ mMM scores as prognostic biomarkers. A nested RCT will ev…
A new kidney transplant biomarker could predict complications, while a follow-up trial tests if switching to abatacept improves function and…