Systematic review links gut microbiota dysbiosis to CKD-MBD, RA, OA, and OP pathogenesis
Your gut holds the key to your bone health
This systematic review examines the role of gut microbiota dysbiosis in chronic kidney disease-mineral and bone disorder (CKD-MBD), rheumato…
Gut bacteria directly influence bone strength and kidney health, yet current treatments ignore the digestive system where the real problem s…
Mental health syndemics reduce ART adherence and impair viral suppression in people living with HIV
When HIV and Depression Collide, Treatment Suffers
This systematic review and meta-analysis of 32 studies involving people living with HIV (PLWH) examined the impact of mental health-related …
When depression, trauma, and poverty pile onto HIV, people struggle more to take their meds and keep the virus in check.
Hungarian app use associated with lower reported antibiotic, antipyretic, and doctor visit use in children
Parents Using This Fever App Reached for Antibiotics Less Often
This prospective cohort registry evaluated Hungarian app users and their children aged 0 to 18 years.
A large real-world registry suggests a guided fever-tracking app may help parents feel confident enough to skip unnecessary meds and appoint…
Podocyte morphometrics correlate with albuminuria and eGFR decline in IgA nephropathy cohort
Tiny Footprints Predict Kidney Disease Progression
A single-center observational cohort of 37 patients with glomerulonephritis found that high-resolution podocyte morphometrics correlated wit…
Tiny changes in kidney cell shapes now predict disease progression better than standard tests, offering earlier warnings for patients with I…
Vim-targeted tremor surgery shows substantial tremor improvement across various targeting approaches
Deep brain stimulation for tremor shows consistent improvement across different targeting methods
A systematic review and meta-analysis of 211 patients undergoing Vim-targeted tremor surgery found substantial tremor improvement across ana…
Surgery targeting a specific brain area consistently reduces severe tremor regardless of the surgical guidance method used, offering reliabl…
Electrolyte homeostasis adaptations in pregnancy require distinct norms to avoid misclassifying abnormalities and delaying care
Are standard lab tests hiding dangerous electrolyte problems in pregnant women?
This systematic review examined physiological adaptations and clinical disturbances of electrolyte homeostasis in pregnant women compared to…
Standard lab tests often misclassify normal pregnancy changes as dangerous problems, delaying care for both mother and baby.
Urinary podocin and nephrin show poor short-term prediction of DKD progression in type 2 diabetes
Could a single urine test predict kidney failure in one year? The answer is no
A retrospective cohort study of 119 adults with type 2 diabetes and DKD found that single baseline measurements of urinary podocin, nephrin,…
Patients with type 2 diabetes cannot rely on a single urine test to predict kidney failure over the next 12 months.
UK retrospective cohort study of tolvaptan prescribing in ADPKD reveals significant variation in initiation and substantial national costs
UK Kidney Centers Miss Out on Life-Saving Drug for Millions
This retrospective cohort study analyzed tolvaptan prescribing patterns among 3,609 people with autosomal dominant polycystic kidney disease…
Over 12 million people with a genetic kidney disease worldwide are missing out on a life-saving drug because UK doctors aren't always prescr…
Retrospective study identifies predictors for dialysis access steal syndrome in ESRD patients
Study identifies factors that may predict dialysis access steal syndrome risk
A retrospective cohort study of 324 ESRD patients found 26.5% developed dialysis access steal syndrome (DASS).
A new model predicts dialysis access steal syndrome risk using patient frailty, body mass, and surgeon experience to help doctors spot dange…
Novel nomogram predicts long-term survival after TIPS in decompensated cirrhosis
Can we better predict survival for cirrhosis patients getting TIPS treatment?
A retrospective single-center cohort study of 409 patients with decompensated cirrhosis undergoing first TIPS developed and validated a nomo…
A new prediction tool outperforms standard scores at estimating how long patients with advanced liver disease will survive after a major shu…
Serenity therapy reduces symptoms and improves coping in geriatric hemodialysis patients
Can a calming therapy ease the heavy burden of dialysis for older patients?
An 80-patient randomized controlled trial in Egyptian geriatric hemodialysis patients found serenity therapy significantly reduced hemodialy…
Serenity therapy significantly reduced dialysis symptoms and improved emotional coping for older patients in a new Egyptian study.
Hispanic/Latinx adults with IgAN show rapid eGFR decline and high kidney event rates in retrospective cohort
Study describes kidney disease progression in Hispanic adults with IgA nephropathy
A retrospective case series of 259 Hispanic/Latinx adults with biopsy-proven IgAN in a U.S.
Hispanic adults with IgA nephropathy face a rapid kidney function decline, with nearly one-third losing over 5 ml/min annually and reaching …