Serum PAI-1, MMP-9, and NLR are higher in elderly acute ischemic stroke patients.
Three Blood Markers Together Predict Stroke Recovery Better Than One Score Alone
In this prospective observational cohort study of 113 elderly acute ischemic stroke patients and 63 elderly controls, serum levels of PAI-1,…
Adding three blood proteins to a standard stroke score better predicts recovery at 90 days for older adults who have just had a clot-based s…
Robot-assisted stereotactic brain biopsy showed shorter operative time versus frame-based biopsy in 54 patients.
Robotic Brain Biopsies Are Faster and Just as Safe as the Old Method
This retrospective cohort study evaluated 54 patients undergoing stereotactic brain biopsy at Jiangxi Provincial People's Hospital. The 3D r…
A new robotic system for brain biopsies cuts operating time significantly while matching the safety and precision of the traditional frame-b…
Abdominal acupuncture added to tDCS improves post-stroke depression in randomized trial
Abdominal acupuncture plus tDCS showed better results than tDCS alone for post-stroke depression in a small trial.
In a randomized trial of 126 patients with post-stroke depression (90 analyzed after 1:1 propensity score matching), abdominal acupuncture a…
Adding abdominal acupuncture to standard tDCS therapy improved depression, daily function, and sleep quality in stroke patients more than tD…
Auricular electroacupuncture raises tracheotomy extubation success after stroke versus swallowing electrical stimulation
Can a specific needle treatment help stroke patients breathe without a breathing tube sooner?
This randomized trial of 84 post-stroke tracheotomy patients compared auricular electroacupuncture plus routine care against swallowing elec…
Adding ear and throat needles to standard care helped stroke patients remove breathing tubes faster, cough stronger, and swallow safer than …
Acupuncture frequency affects aphasia outcomes post-stroke in randomized trial
Does acupuncture speed up speech recovery after stroke, and does the needle speed matter?
This randomized controlled trial in 105 patients with post-ischemic stroke aphasia compared low-frequency and high-frequency acupuncture at …
Slowly twirling acupuncture needles helped stroke patients recover speech and understanding better than fast needles or fake needles after s…
Protocol for cane training trial in Parkinson's disease to assess gait speed and confidence.
Could simple cane training help people with Parkinson's walk faster and feel safer?
This is a protocol for a randomized controlled trial in 26 individuals with Parkinson's disease. It will compare cane training and use to gl…
A new trial tests whether four cane training sessions can help people with Parkinson's walk faster and feel safer, addressing freezing of ga…
Oral cladribine reshapes CSF immune cell composition in relapsing multiple sclerosis
Cladribine therapy changes immune cells in fluid from the brain in a small MS study
This single-site phase IV clinical trial used single-cell sequencing on CSF and blood from 13 individuals with relapsing MS before and after…
Cladribine therapy reshapes immune cells in the brain's fluid by reducing harmful memory B cells while boosting protective Treg cells in mul…
Protocol for pilot RCT of neuromodulation-augmented balance training in ambulatory people with multiple sclerosis
New Balance Trick Helps MS Walkers Move Better
This published protocol describes a pilot randomized trial evaluating the feasibility, acceptability, safety, and preliminary clinical effic…
This new approach combines simple exercises with gentle electrical signals to help people with multiple sclerosis walk more confidently.
Elevated monocyte-to-HDL ratio associated with stroke predisposition in U.S. adults.
High monocyte-to-HDL cholesterol ratio linked to higher stroke risk in adults
This cross-sectional study of 43,321 U.S. adults from NHANES found an elevated monocyte-to-HDL cholesterol ratio (MHR) was statistically sig…
High monocyte-to-HDL cholesterol ratios are linked to a higher risk of stroke in U.S. adults, based on data from over 43,000 people.
Tenecteplase shows worse functional outcomes in older patients with minor ischemic stroke compared to standard care.
The Clot-Busting Drug That Backfires in Patients Over 80
This post hoc analysis of a randomized controlled trial evaluated tenecteplase versus nonthrombolytic standard of care in 884 patients with …
In patients over 80 with minor stroke, a clot-busting drug improved short-term recovery but worsened outcomes at 90 days compared to standar…
MRI outcomes show weak association with disability in primary progressive multiple sclerosis patients
MRI results show weak connection to disability changes in progressive multiple sclerosis
This Phase 3 trial secondary analysis evaluated 943 patients with primary progressive multiple sclerosis treated with glatiramer acetate ove…
MRI scans show weak links to disability changes in progressive multiple sclerosis, challenging their use as reliable trial endpoints for thi…
6-week multimodal exercise training feasible for frail people with multiple sclerosis in pilot RCT
Exercise Helps Frail MS Patients Feel Better
This pilot randomized controlled trial in 16 frail people with multiple sclerosis tested a 6-week multimodal exercise program versus waitlis…
A new exercise program combining virtual reality and resistance training helps frail people with multiple sclerosis feel better and move mor…