Posttraumatic growth scores increase gradually each month after stroke discharge
Stroke survivors may experience gradual personal growth in the months after hospital discharge
A systematic review and meta-regression of 10 observational studies including 1,046 stroke survivors found PTG scores increased significantl…
Stroke survivors often feel stronger and find new meaning in the months after leaving the hospital, with personal growth gradually increasin…
Review explores L-carnitine mechanisms for MASLD, a condition affecting over one-third globally
Review explores how supplement L-carnitine might help with common fatty liver disease
A systematic review article summarizes the global burden of MASLD and the proposed mechanisms of L-carnitine. The supplement is theorized to…
L-carnitine might help fatty liver disease by improving how the liver burns fat and reducing inflammation, though human trials are still nee…
Extracellular histones drive thrombo-inflammation in sepsis, stroke, and ARDS, review finds
Could tiny proteins released during cell death be making blood clots worse?
A systematic review synthesizes evidence on extracellular histones as damage-associated molecular patterns (DAMPs) in thrombo-inflammatory c…
Tiny proteins released when cells die may trigger dangerous blood clots and inflammation in severe illnesses like sepsis and stroke, offerin…
Nanozyme-based delivery systems show theoretical antibacterial mechanisms for osteomyelitis treatment
Review explores how nanozyme-based systems might help treat bone infections
A systematic review of preclinical evidence found that nanozymes have enzyme-mimicking activities that generate reactive oxygen species and …
Nanozymes might fight tough bone infections by breaking bacterial shields and generating substances that kill germs, though this is still ea…
Brain bank series finds 47% clinical-pathological concordance in primary tauopathies
Brain bank study finds clinical diagnosis often differs from autopsy findings in tau diseases
A systematic review of 15 brain donation cases from a single national brain bank (1994-2022) identified several primary tauopathy types with…
Doctors guessed the right brain disease only 47% of the time, while autopsy proved the true diagnosis in most cases.
Evidence summary synthesizes 18 best practice recommendations for post-stroke shoulder-hand syndrome care
What's the best care for stroke survivors with painful shoulder-hand syndrome?
An evidence summary synthesized 18 best practice recommendations for physical therapy and nursing in patients with post-stroke shoulder-hand…
Stroke survivors with painful shoulder-hand syndrome now have 18 specific care recommendations to standardize treatment and help rehabilitat…
FDA Approves Depakote Sprinkle Capsules (valproate) for Monotherapy and Adjunctive Therapy of Complex Partial and Absence Seizures.
FDA approves a new sprinkle capsule form of the epilepsy drug Depakote.
The FDA approved Depakote Sprinkle Capsules (valproate) for monotherapy and adjunctive therapy of complex partial seizures and simple and co…
FDA approves a sprinkle capsule form of Depakote that patients can open and mix with soft food to help those who struggle to swallow pills.
Review suggests glial scar-inflammation axis may contribute to poor outcomes after CSM surgery
Review suggests inflammation and scar tissue may affect recovery after neck surgery
A systematic review examining postoperative mechanisms in cervical spondylotic myelopathy suggests the glial scar–inflammation axis may be a…
Inflammation and scar tissue around the spinal cord may block healing and cause symptoms to return after neck surgery for severe spinal cord…
Narrative review explores diagnostic controversies between status epilepticus and ictal-interictal continuum
Review explores diagnostic uncertainty between seizure continuum and status epilepticus
A narrative review examines the uncertain boundaries between status epilepticus and the ictal-interictal continuum, highlighting diagnostic …
Doctors struggle to tell apart dangerous status epilepticus from a confusing brain wave pattern that sits in a gray zone between normal and …
Bibliometric analysis identifies 100 most-cited articles on proton therapy for glioma
Where is the research on proton therapy for brain tumors heading?
A bibliometric analysis of 100 highly-cited articles on proton therapy for glioma found the United States leads in publications, with Massac…
A new analysis of the top 100 studies on proton therapy for brain tumors shows the United States leads the field, with Massachusetts General…
Anosognosia and Theory of Mind Deficits Independently Associated with Caregiver Distress in Dementia
Why do some dementia caregivers feel more distress? Two key patient traits may explain it.
A cross-sectional secondary analysis of 205 participants with various dementia syndromes found that anosognosia and theory of mind deficits …
When a person with dementia lacks awareness of their decline or struggles to understand others, it adds up to greater distress for their car…
Meta-analysis finds Icariin improves cognition in Alzheimer's animal models at 68 mg/kg dose
Icariin compound shows promise for improving memory in Alzheimer's animal studies
A systematic review and meta-analysis of 31 preclinical studies in Alzheimer's disease animal models found Icariin treatment significantly i…
A natural compound called Icariin improved memory and thinking in animal models of Alzheimer's disease by protecting brain cells from damage…