Pragmatic approach addresses post-stroke insomnia through objective sleep phenotyping and coordinated management of dominant drivers
Stroke survivors sleep better with this new approach
This narrative review outlines a pragmatic, mechanism-informed strategy for managing post-stroke insomnia. It emphasizes objective sleep phe…
Stroke survivors with insomnia may sleep better when doctors match treatments to the specific cause of their sleep problem.
Meta-analysis of taVNS for stroke motor function shows significant improvement
Stroke recovery improves with a tiny ear clip and gentle electrical pulses
This meta-analysis of randomized trials synthesized evidence on transcutaneous auricular vagus nerve stimulation (taVNS) for stroke. The aut…
A gentle ear clip that taps a key nerve may help stroke survivors move better and feel calmer.
Systematic review synthesizes urgent venous sinus stenting for fulminant idiopathic intracranial hypertension
A New Stent Procedure Could Save Your Eyesight in Days
This systematic review synthesized outcomes of urgent venous sinus stenting in 23 patients with fulminant idiopathic intracranial hypertensi…
When standard treatments fail and eyesight starts slipping fast, a vein-opening stent in the skull may stop vision loss within days.
Review discusses oxidized lipids in carotid artery stenting and in-stent restenosis pathophysiology
New Clue Found in Carotid Artery Stent Clog Problem
This narrative review examines the role of oxidized lipids in patients undergoing carotid artery stenting. The authors note that oxidative s…
Oxidized fats may be the hidden trigger behind artery narrowing after carotid stenting, offering a new target for prevention.
Argatroban plus alteplase shows no daytime benefit but nighttime association with better stroke outcomes
Stroke drug works better at night than in the morning
This post hoc analysis of a phase 3 RCT in 692 patients with acute ischemic stroke found no significant difference in excellent functional o…
Nighttime stroke treatment with argatroban plus alteplase may improve recovery, while daytime use showed no added benefit.
Meta-analysis links loneliness to Alzheimer's disease and suicidal behavior outcomes
Loneliness linked to higher Alzheimer's and suicide risk
This meta-analysis of observational studies synthesized associations between loneliness and Alzheimer's disease, suicidal ideation, planning…
A major review finds loneliness raises Alzheimer's and suicide risks. The link is strong across many studies.
Network meta-analysis of pediatric atopic dermatitis treatments shows dupilumab and pimecrolimus efficacy
Dupilumab and Pimecrolimus Lead New Rankings for Children's Eczema Relief
This network meta-analysis evaluated dupilumab, pimecrolimus, melatonin, probiotics, tralokinumab, nemolizumab, and vitamin D for pediatric …
A new analysis ranks the top treatments for children's eczema, with dupilumab and pimecrolimus leading for symptom relief.
Review of in vitro methods for foot-and-mouth disease vaccine immunogenicity assessment
Scientists explore new lab tests to check foot-and-mouth disease vaccine strength without using animals
This narrative review synthesizes evidence on in vitro approaches for assessing foot-and-mouth disease vaccine immunogenicity, compared to t…
A review looks at lab tests that check how well vaccines work against foot-and-mouth disease. These new methods might help reduce the need f…
Systematic review and meta-analysis finds 30.2% success rate for MVD in TN-MS patients
MVD surgery shows about 30 percent success for trigeminal neuralgia in MS patients
This systematic review and meta-analysis of 429 TN-MS patients treated with microvascular decompression (MVD) found a pooled success rate of…
A review of 429 patients found microvascular decompression surgery relieved facial pain for about 30 percent of people with both conditions.
Systematic review of post-stroke delirium prediction models finds moderate discriminative ability
New Tools Help Spot Confusion After a Stroke
This systematic review and meta-analysis synthesized 12 studies constructing 21 risk prediction models for post-stroke delirium. The combine…
Doctors can now spot dangerous confusion after a stroke more accurately using new prediction tools that look at age and heart health.
Meta-analysis finds robot-assisted training plus acupuncture improves stroke recovery outcomes
Robot Therapy Plus Acupuncture Helps Stroke Survivors Walk Better
This systematic review and meta-analysis of 1821 stroke patients found that robot-assisted training plus acupuncture therapy significantly i…
Stroke survivors who get robot therapy plus acupuncture walk farther and regain more leg strength than with either treatment alone.
FDA Approves Nuplazid (pimavanserin) for Parkinson's Disease Psychosis
FDA approves first drug for hallucinations in Parkinson's disease
The FDA approved Nuplazid (pimavanserin) for hallucinations and delusions associated with Parkinson's disease psychosis. Approval was based …
The FDA approved Nuplazid (pimavanserin) to treat hallucinations and delusions in people with Parkinson's disease psychosis. It is the first…