Prolonged conservative treatment yields 58% complete response in endometrial hyperplasia and carcinoma
Longer conservative treatment may work for some uterine tissue conditions
This meta-analysis of 10 studies (846 women) assessed oncological outcomes of conservative treatment lasting more than 12 months in atypical…
Women with certain types of uterine cell growth may have options for longer, less invasive treatments under close medical supervision.
Magnetic seeds for pre-operative localisation significantly reduce re-excision rates compared to wire-guided localisation
Magnetic Seeds May Reduce Re-excision Rates in Breast Cancer Surgery
This meta-analysis of 16 studies evaluated magnetic seeds versus wire-guided localization for non-palpable breast lesions. The analysis foun…
Magnetic seeds may offer an effective alternative to wire guidance, potentially leading to smaller resection sizes and fewer repeat surgerie…
PRP growth factors converge on PI3K–AKT and MAPK pathways in ovarian follicular development
PRP may boost ovarian signaling pathways, study finds
A systematic mechanistic review and computational pathway analysis found that growth factors in platelet-rich plasma (PRP) converge on PI3K–…
A computational analysis suggests PRP may activate key ovarian signaling pathways, but does not replace natural follicle development.
Evidence does not support prolonged maintenance ritodrine as routine care for threatened preterm labor
New Guidelines Address Safety Concerns for Preterm Labor Medication
This clinical guideline addresses the management of threatened preterm labor in Japan. The authors synthesize evidence regarding tocolysis a…
New clinical guidelines in Japan address the risks of using ritodrine for preterm labor to improve safety for both mothers and newborns.
Group support models may improve PrEP uptake and adherence for adolescent girls and young women
Group support models improve HIV prevention for young women
This scoping review of 11 studies examined group support models for HIV prevention in sub-Saharan Africa. The findings suggest these interve…
Peer support and education can help young women in Africa feel more confident and stay on their HIV prevention medication.
Impact of Physical Activity Interventions on Exercise Levels in Breast Cancer Patients
Physical activity programs show promise for women with breast cancer
Meta-analysis reveals that structured physical activity programs significantly increase exercise levels in women with breast cancer over sho…
New research shows that exercise programs can increase physical activity levels for women living with or beyond a breast cancer diagnosis.
Discordant treatment responses between primary and metastatic sites occur in 25.1% of stage IV breast cancer
Treatment response differences between primary and metastatic sites impact survival
This exploratory analysis of a Phase III trial involved 271 patients with de novo stage IV breast cancer receiving primary systemic therapy.…
New data shows that when breast cancer responds differently at the original site versus other areas, it can affect patient outcomes.
Axillary lymph node dissection increases risk of arm swelling and lymphoedema in breast cancer patients
Trial Shows Axillary Surgery Predicts Long Term Arm Swelling
This randomized controlled trial of 469 patients undergoing surgery and radiotherapy for node-positive breast cancer found that axillary lym…
New research shows that axillary lymph node dissection is a primary predictor of long-term arm swelling for patients after breast cancer tre…
Immune-epigenetic-metabolic crosstalk drives immune evasion and promotes disease progression in endometriosis
Immune and Metabolic Changes Linked to Endometriosis Progression
This systematic review synthesizes the mechanisms by which metabolic reprogramming, epigenetic modifications, and immune cell dysfunction in…
New research highlights how a mix of immune, genetic, and metabolic changes may help endometriosis cells evade the body's natural defenses.
Multi-method approach increases detection of nonadherent patients by 49.4%-69.0% in breast cancer
New methods help doctors track breast cancer medication use
This randomized controlled trial evaluated self-report tools versus refill-based metrics for oral anticancer medication adherence in 500 bre…
A new approach combining patient reports with pharmacy data helps doctors better identify patients who might be struggling to take their med…
Astaxanthin may serve as a potential adjuvant treatment for PCOS by addressing oxidative stress and inflammation
Astaxanthin Shows Potential to Manage Polycystic Ovary Syndrome Symptoms
This systematic review explores the therapeutic potential of astaxanthin for Polycystic ovary syndrome (PCOS) through antioxidant, anti-infl…
Astaxanthin may help manage symptoms of Polycystic Ovary Syndrome (PCOS) by reducing inflammation and improving insulin sensitivity in the b…
Tamoxifen improves 20-year distant recurrence-free interval for Luminal A and B breast cancer
Tamoxifen reduces long-term breast cancer recurrence in specific subtypes
This secondary analysis of a randomized controlled trial involving 952 patients with estrogen receptor-positive and HER2-negative tumors fou…
A 20-year follow-up shows that tamoxifen significantly lowers the risk of distant cancer recurrence for patients with luminal A and B tumors…