EGFR inhibitors show reproducible activity and manageable toxicity in locally advanced or metastatic anal squamous cell carcinoma
EGFR Inhibitors Show Activity in Advanced Anal Squamous Cell Carcinoma
This meta-analysis of 404 patients evaluated EGFR inhibitors (cetuximab and panitumumab) for anal squamous cell carcinoma. The analysis foun…
New analysis shows that EGFR inhibitors like cetuximab and panitumumab may improve response rates for patients with advanced anal squamous c…
KYR intervention is non-inferior to conventional genetic counseling in breast cancer risk knowledge
Online genetic counseling works as well as in-person for high-risk women
This randomized trial of 866 women at elevated risk for breast cancer found the KYR intervention was non-inferior to conventional genetic co…
A new trial shows that online genetic counseling is just as effective as traditional in-person sessions for women at elevated breast cancer …
Higher log GDP per capita is associated with higher Comprehensive Score for Financial Toxicity
Wealthier countries see higher costs for patients with cancer
This meta-analysis of 83,623 patients across 75 studies found a pooled mean COST score of 21.2 (95% CI: 19.1-23.3). The analysis identified …
New data shows that while wealthier nations have more resources, their cancer patients often face higher financial toxicity and personal cos…
Meta Analysis Evaluates Hypokalemia Risks Associated with Androgen Receptor Axis Targeted Therapies
New Analysis Shows Risk of Low Potassium with Prostate Cancer Drugs
A meta-analysis of 9,298 patients reveals that abiraterone and combination therapies significantly increase hypokalemia risk in advanced pro…
Certain prostate cancer treatments, especially abiraterone and combination therapies, are linked to a significantly higher risk of low potas…
Rural residence and poor knowledge increase odds of delayed health-seeking behavior for cancer patients
Over half of cancer patients delay seeking medical care
This meta-analysis of observational data from Ethiopia identifies a 54% prevalence of delayed health-seeking behavior among cancer patients.…
More than half of cancer patients in Ethiopia delay seeking treatment due to factors like rural living and lack of awareness.
Multicomponent nonpharmacological interventions reduce delirium incidence in adult patients with cancer
Non-drug approaches cut delirium risk in cancer patients
This meta-analysis evaluated various nonpharmacological interventions to determine their impact on delirium incidence in adult cancer patien…
A review of 2,747 patients finds that multicomponent non-drug interventions can reduce delirium in cancer patients, especially after surgery…
Neurotoxic chemotherapy causes moderate to large increases in vibration perception threshold in hands and feet
Chemotherapy Linked to Loss of Sensation in Hands and Feet
This meta-analysis of 1635 patients receiving neurotoxic chemotherapy found significant increases in vibration perception threshold (VPT) in…
New analysis shows that certain chemotherapy drugs can cause a significant loss of sensation in the hands and feet for many patients.
Multidimensional models incorporating genomic and microenvironment features likely outperform single-analyte tests to predict immunotherapy response
Multi-Omic Biomarkers May Improve Lung Cancer Treatment Predictions
This narrative review explores the integration of chemokine signatures and multi-omic biomarkers to predict immune checkpoint inhibitor resp…
New research suggests that combining multiple biological markers can better predict how lung cancer patients will respond to immunotherapy.
miRNA panels show high diagnostic accuracy for endometrial cancer in meta-analysis
miRNA Panels Show High Accuracy for Endometrial Cancer Diagnosis
This meta-analysis of 531 participants found that miRNA panels have high diagnostic accuracy for endometrial cancer, with pooled sensitivity…
A new analysis finds miRNA panels may accurately detect endometrial cancer, but more research is needed before routine use.
Radiomics-based artificial intelligence models predict VETC presence in patients with hepatocellular carcinoma
AI helps predict aggressive liver cancer growth patterns
Researchers evaluated the diagnostic accuracy of radiomics-based AI models using various imaging modalities to identify vessel-encapsulated …
New AI tools can identify specific high-risk markers in liver cancer scans, helping doctors better predict which tumors are likely to return…
Liquid biopsy technologies utilizing NGS and machine learning improve analytical sensitivity for early cancer detection
Liquid Biopsies Show Promise for Early Multi-Cancer Detection
This mini-review synthesizes current literature on liquid biopsy modalities including ctDNA, exosomes, and epigenetic fingerprints for multi…
New liquid biopsy technologies use machine learning and advanced testing to detect multiple types of cancer early through a simple blood sam…
Acupuncture promotes microglial transition from pro-inflammatory glycolysis to anti-inflammatory oxidative phosphorylation metabolism
Acupuncture May Tame Brain Inflammation by Changing Energy Use
This systematic review explores the mechanisms of acupuncture in neuroinflammation, specifically focusing on microglial glucose metabolism r…
Acupuncture may calm brain inflammation by shifting immune cells from a pro-inflammatory to an anti-inflammatory state.