Physical exercise during neoadjuvant chemotherapy does not significantly improve pathologic complete response in solid tumors
Exercise and chemotherapy results for several types of cancer
This meta-analysis of 504 patients with breast, esophageal, gastric, or rectal cancer found no significant difference in pathologic complete…
New data looks at how exercise affects how well chemotherapy shrinks tumors in patients with breast, esophageal, gastric, and rectal cancers…
Trial protocol evaluates 9-month ADT plus ARTA for high-risk prostate cancer non-inferiority
New trial tests shorter hormone therapy for high-risk prostate cancer
This Phase II trial protocol evaluates 9 months of androgen deprivation therapy (ADT) plus 6 months of an androgen receptor-targeted agent (…
A new clinical trial is testing if a shorter, more intense hormone treatment can work just as well as standard care for high-risk prostate c…
PD-1/PD-L1 inhibitor plus chemotherapy improves overall survival in advanced gastric and esophageal junction cancer
PD-1 Inhibitors Plus Chemotherapy Improve Survival in Gastric Cancer
This meta-analysis of 6,517 patients found that PD-1/PD-L1 inhibitor plus chemotherapy significantly improved overall survival (HR, 0.79) an…
Combining PD-1 or PD-L1 inhibitors with chemotherapy shows improved survival and response rates for patients with advanced gastric or esopha…
Gut Microbiome and Metabolites May Modulate Thyroid Cancer Immunity and Treatment Response
Gut bacteria and metabolites may influence thyroid cancer treatment
This narrative review examines how gut dysbiosis, bacterial outer membrane components such as lipopolysaccharides, and metabolites including…
Your gut health might play a hidden role in how your body responds to thyroid cancer treatments and immune system interactions.
SCRT plus ICI associated with higher CR and pCR rates than LCRT in rectal cancer
Specific radiation types may improve outcomes for rectal cancer patients
This meta-analysis of 972 patients with pMMR or MSS locally advanced rectal cancer found that SCRT plus ICI yielded higher CR and pCR rates …
Adding certain immunotherapy drugs to specific types of radiation may improve response rates for patients with advanced rectal cancer.
BRCA1 or BRCA2 mutations correlate with improved survival and platinum sensitivity in ovarian cancer
BRCA Mutations Linked to Better Ovarian Cancer Survival
This systematic review examines the impact of BRCA1 and BRCA2 mutation status on treatment outcomes in ovarian cancer patients. The review f…
Women with ovarian cancer and BRCA mutations may live longer and respond better to certain treatments, a review finds.
D-dimer elevated in high-risk multiple myeloma with pooled SMD of 1.60
D-dimer levels higher in high-risk multiple myeloma patients
This meta-analysis examined plasma D-dimer levels in patients with multiple myeloma, comparing high-risk groups (advanced ISS stage, venous …
A new analysis finds D-dimer levels are much higher in multiple myeloma patients at high risk for complications. This simple blood test coul…
Hypofractionated whole-breast irradiation is associated with the lowest ipsilateral breast recurrence rates in early-stage breast cancer
Hypofractionated Radiation Shows Lower Recurrence Rates in Early Breast Cancer
This systematic review and network meta-analysis of 32,655 patients found that hypofractionated whole-breast irradiation (HF-WBI) is associa…
A large review of over 32,000 patients suggests that hypofractionated radiation may lower recurrence rates in early-stage breast cancer.
Empowered Survivor digital tool boosts self-efficacy in oral cancer survivors
Digital Intervention Improves Self-Care for Oral Cancer Survivors
In a randomized trial of 643 oral/oropharyngeal cancer survivors, the Empowered Survivor digital intervention improved self-efficacy at 2 an…
A new digital program helps oral cancer patients feel more confident and perform more self-care activities like swallowing and mobility exer…
Objective response rate correlates with overall survival in nivolumab-containing regimens for metastatic melanoma
Nivolumab regimens show link between tumor shrinkage and melanoma survival
This meta-analysis of 1865 treatment-naive patients with metastatic melanoma evaluated the association between clinical surrogates and overa…
New data shows that shrinking tumors and staying stable provides a strong link to longer survival for patients with metastatic melanoma.
Bispecific antibodies improve progression-free survival and overall survival in patients with solid tumors
Bispecific antibodies improve survival for patients with solid tumors
This meta-analysis of 3505 patients with solid tumors found that bispecific antibodies significantly improved progression-free survival (HR …
A new type of antibody treatment shows promise in extending life and slowing cancer growth for patients with solid tumors.
Sutureless renorrhaphy is noninferior to conventional renorrhaphy for trifecta achievement in robot-assisted partial nephrectomy
Sutureless Technique Shows No Difference in Renal Cancer Surgery
This meta-analysis of 787 patients evaluated sutureless renorrhaphy versus conventional renorrhaphy in robot-assisted off-clamp partial neph…
A sutureless technique for closing the kidney during surgery shows similar results to traditional methods for patients with renal cancer.