Evaluating Chemoimmunotherapy versus Monotherapy for Advanced NSCLC Patients with High PD-L1 Expression
Adding Chemotherapy to Immune Therapy for Lung Cancer Shows Mixed Results
A meta-analysis of 3,252 patients reveals that adding chemotherapy to ICI monotherapy does not provide a consistent survival advantage.
New analysis suggests that adding chemotherapy to immunotherapy for certain lung cancers may not provide a consistent survival benefit over …
Shear Wave Elastography Shows Promise in Predicting Breast Cancer Response
Ultrasound Technique Shows Promise for Breast Cancer Treatment Response
A meta-analysis of 1402 patients finds shear wave elastography moderately predicts pathological response to neoadjuvant chemotherapy in brea…
A new review suggests shear wave elastography may help predict if breast cancer responds to chemo before surgery, aiding treatment decisions…
ICIs Boost pCR in Early Triple-Negative Breast Cancer
Immune drugs combined with chemotherapy improve results for triple-negative breast cancer
Adding immune checkpoint inhibitors to chemotherapy improves pathological complete response in early triple-negative breast cancer, with PD-…
Adding immune checkpoint inhibitors to chemotherapy significantly increases the chance of clearing cancer cells in triple-negative breast ca…
Long-term exercise significantly attenuates cardiac troponin I elevation in anthracycline-treated breast cancer patients
Long-term Exercise May Protect Heart Health After Breast Cancer Treatment
This meta-analysis of randomized controlled trials evaluated the impact of long-term exercise on cardiac markers in breast cancer patients t…
Long-term exercise may help reduce certain markers of heart damage in breast cancer patients treated with anthracyclines.
SGLT2 inhibitors not tied to gastrointestinal cancer risk in type 2 diabetes meta-analysis
SGLT2 inhibitors show no link to gastrointestinal cancer risk
This meta-analysis of 48,765 patients with type 2 diabetes found no significant association between SGLT2 inhibitor use and overall or site-…
New data suggests that SGLT2 inhibitors, a common treatment for type 2 diabetes, do not increase the risk of various gastrointestinal cancer…
Post-translational modifications drive drug resistance in hepatocellular carcinoma, systematic review finds
Chemical Changes in Proteins May Help Overcome Drug Resistance in Liver Cancer
This systematic review synthesizes evidence that post-translational modifications (PTMs), including phosphorylation, ubiquitination, acetyla…
Scientists are looking at how specific chemical changes to proteins can help doctors fight liver cancer that does not respond well to standa…
Plant-derived bioactive compounds may offer neuroprotective effects and alleviate late-life depression in older adults
Plant compounds may help protect the brain from late-life depression
This narrative review explores the potential of plant-derived bioactive compounds, including polyphenols and terpenoids, for managing late-l…
Certain plant-based compounds like polyphenols and terpenoids may offer a way to protect the brain and ease symptoms of depression in older …
FDA Approves Etopophos (etoposide phosphate) for Refractory Testicular Tumors and Small Cell Lung Cancer
FDA approves new form of chemotherapy drug for two cancers
The FDA approved Etopophos (etoposide phosphate) for refractory testicular tumors and small cell lung cancer. In a clinical trial for small …
The FDA has approved Etopophos, a new form of the chemotherapy drug etoposide, to treat testicular cancer and small cell lung cancer. It is …
FDA Approves Fyarro (nab-sirolimus) for Malignant PEComa
FDA approves new drug Fyarro for rare soft tissue cancer PEComa
The FDA has approved Fyarro (nab-sirolimus) for adult patients with locally advanced unresectable or metastatic malignant perivascular epith…
The FDA has approved Fyarro (nab-sirolimus) for adults with advanced PEComa, a rare soft tissue sarcoma. This is the first treatment specifi…
EGFR-TKI plus anti-angiogenic therapy shows HR 0.63 for overall survival in NSCLC with brain metastases
Combination therapies show promise for lung cancer with brain spread
This systematic review and network meta-analysis of 5432 patients with EGFR-mutated non-small cell lung cancer and brain metastases found th…
New data suggests that combining specific drugs can improve survival and slow cancer growth in patients with lung cancer that has spread to …
Adherence to clinical practice guidelines improves survival for Stage II and III colon cancer
Following specific guidelines may improve survival for some colon cancers
This meta-analysis of 30 studies evaluated the impact of colorectal cancer clinical practice guideline (CPG) adherence on overall survival. …
Following specific clinical guidelines for Stage II and Stage III colon cancer may improve survival rates for patients with these specific s…
Neurosurgical management is essential for rare cerebral metastases from non-DES-related vaginal clear cell adenocarcinoma
Rare Case Shows Brain Metastasis from Vaginal Clear Cell Cancer
This case report and literature review describes a 17-year-old female with non-DES-related primary clear cell adenocarcinoma of the vagina (…
A rare case of vaginal clear cell adenocarcinoma spreading to the brain highlights the need for clear management guidelines for this specifi…